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Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

Nature medicine, 2015-05, Vol.21 (5), p.457-466

2015

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Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10

Scientific reports, 2021-06, Vol.11 (1), p.12900-12900, Article 12900

2021

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Small-Molecule Inhibition of the Interaction between the Translation Initiation Factors eIF4E and eIF4G

Cell, 2007-01, Vol.128 (2), p.257-267

2007

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Ribosome Loading onto the mRNA Cap Is Driven by Conformational Coupling between eIF4G and eIF4E

Cell, 2003-12, Vol.115 (6), p.739-750

2003

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Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation

Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (8), p.3383-3388

2011

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Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis

Molecular systems biology, 2015-03, Vol.11 (3), p.797-797

2015

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Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases

Journal of medicinal chemistry, 2024-04, Vol.67 (7), p.5758-5782

2024

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A high-throughput, cell-based screening method for siRNA and small molecule inhibitors of mTORC1 signaling using the In Cell Western technique

Assay and drug development technologies, 2010-04, Vol.8 (2), p.186-199

2010

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Assay Development and High-Throughput Screening for Inhibitors of Kaposi's Sarcoma-Associated Herpesvirus N-Terminal Latency-Associated Nuclear Antigen Binding to Nucleosomes

Journal of biomolecular screening, 2014-07, Vol.19 (6), p.947-958

2014

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Systematic analysis of BRAFV600E melanomas reveals a role for JNK/c‐Jun pathway in adaptive resistance to drug‐induced apoptosis

Molecular systems biology, 2015-03, Vol.11 (3), p.1-n/a

2015

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Fluorescence Polarization (FP) Assays for Monitoring Peptide‐Protein or Nucleic Acid‐Protein Binding

Current protocols in chemical biology, 2009-12, Vol.1 (1), p.1-15

Moerke, Nathan J.

2009

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Abstract 3744: Single-cell analysis of adaptive resistance and fractional responses of melanoma cells to RAF/MEK inhibition

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.3744-3744

2015

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Systematic analysis of BRAF V 600E melanomas reveals a role for JNK /c‐Jun pathway in adaptive resistance to drug‐induced apoptosis

Molecular systems biology, 2015-03, Vol.11 (3)

2015

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Abstract 5213: A systems biology approach to understanding differential phenotypic outcome of BRAF(V600E) inhibition in melanoma cells

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.5213-5213

2013

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The Magnitude of the Allosteric Conformational Transition of Aspartate Transcarbamylase Is Altered by Mutations

Biochemistry (Easton), 1998-12, Vol.37 (50), p.17381-17385

1998

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Development of In‐Cell Western Assays Using Far‐Red Fluorophores

Current protocols in chemical biology, 2011-03, Vol.3 (1), p.39-52

2011

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Differential determinants of cancer cell insensitivity to antimitotic drugs discriminated by a one-step cell imaging assay

Journal of biomolecular screening, 2013-10, Vol.18 (9), p.1062-1071

2013

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Folding Transitions During Assembly of the Eukaryotic mRNA Cap-binding Complex

Journal of molecular biology, 2006-03, Vol.356 (4), p.982-992

2006

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Synthesis of fluorescein labeled 7-methylguanosinemonophosphate

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (10), p.2657-2660

2004

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Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10

Small-Molecule Inhibition of the Interaction between the Translation Initiation Factors eIF4E and eIF4G

Ribosome Loading onto the mRNA Cap Is Driven by Conformational Coupling between eIF4G and eIF4E

Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation

Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis

Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases

A high-throughput, cell-based screening method for siRNA and small molecule inhibitors of mTORC1 signaling using the In Cell Western technique

Assay Development and High-Throughput Screening for Inhibitors of Kaposi's Sarcoma-Associated Herpesvirus N-Terminal Latency-Associated Nuclear Antigen Binding to Nucleosomes

Systematic analysis of BRAFV600E melanomas reveals a role for JNK/c‐Jun pathway in adaptive resistance to drug‐induced apoptosis

Fluorescence Polarization (FP) Assays for Monitoring Peptide‐Protein or Nucleic Acid‐Protein Binding

Abstract 3744: Single-cell analysis of adaptive resistance and fractional responses of melanoma cells to RAF/MEK inhibition

Systematic analysis of BRAF V 600E melanomas reveals a role for JNK /c‐Jun pathway in adaptive resistance to drug‐induced apoptosis

Abstract 5213: A systems biology approach to understanding differential phenotypic outcome of BRAF(V600E) inhibition in melanoma cells

The Magnitude of the Allosteric Conformational Transition of Aspartate Transcarbamylase Is Altered by Mutations

Development of In‐Cell Western Assays Using Far‐Red Fluorophores

Differential determinants of cancer cell insensitivity to antimitotic drugs discriminated by a one-step cell imaging assay

Folding Transitions During Assembly of the Eukaryotic mRNA Cap-binding Complex

Synthesis of fluorescein labeled 7-methylguanosinemonophosphate

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