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Introduction to metallic nanoparticles

Journal of pharmacy & bioallied science, 2010-10, Vol.2 (4), p.282-289

2010

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In vitro to clinical translational pharmacokinetic/pharmacodynamic modeling of doxorubicin (DOX) and dexrazoxane (DEX) interactions: Safety assessment and optimization

Scientific reports, 2023-02, Vol.13 (1), p.3100-3100, Article 3100

2023

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Overcoming nucleoside analog chemoresistance of pancreatic cancer: A therapeutic challenge

Cancer letters, 2012-07, Vol.320 (2), p.138-149

2012

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Inhibition of S-Adenosylmethionine-Dependent Methyltransferase Attenuates TGF beta 1-Induced EMT and Metastasis in Pancreatic Cancer: Putative Roles of miR-663a and miR-4787-5p

Molecular cancer research, 2016-11, Vol.14 (11), p.1124-1135

2016

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In vitro to clinical translation of combinatorial effects of doxorubicin and dexrazoxane in breast cancer: a mechanism-based pharmacokinetic/pharmacodynamic modeling approach

Frontiers in pharmacology, 2023-10, Vol.14, p.1239141-1239141

2023

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miR-202 Diminishes TGFβ Receptors and Attenuates TGFβ1-Induced EMT in Pancreatic Cancer

Molecular cancer research, 2017-08, Vol.15 (8), p.1029-1039

2017

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SET contributes to the epithelial-mesenchymal transition of pancreatic cancer

Oncotarget, 2017-09, Vol.8 (40), p.67966-67979

2017

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A quantitative systems pharmacological approach identified activation of JNK signaling pathway as a promising treatment strategy for refractory HER2 positive breast cancer

Journal of pharmacokinetics and pharmacodynamics, 2021-04, Vol.48 (2), p.273-293

2021

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Bench‐to‐bedside translation of chimeric antigen receptor (CAR) T cells using a multiscale systems pharmacokinetic‐pharmacodynamic model: A case study with anti‐BCMA CAR‐T

CPT: pharmacometrics and systems pharmacology, 2021-04, Vol.10 (4), p.362-376

2021

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Pharmacodynamic Modeling to Evaluate the Impact of Cimetidine, an OCT2 Inhibitor, on the Anticancer Effects of Cisplatin

Cells (Basel, Switzerland), 2022-12, Vol.12 (1), p.57

2022

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Inhibition of S-Adenosylmethionine-Dependent Methyltransferase Attenuates TGFβ1-Induced EMT and Metastasis in Pancreatic Cancer: Putative Roles of miR-663a and miR-4787-5p

Molecular cancer research, 2016-11, Vol.14 (11), p.1124-1135

2016

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Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies

PloS one, 2013-08, Vol.8 (8), p.e71196

2013

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Clinical Pharmacology Considerations for the “Off‐the‐Shelf” Allogeneic Cell Therapies

Clinical pharmacology and therapeutics, 2024-06, Vol.115 (6), p.1233-1250

2024

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Abstract 3421: Pharmacological inhibition of histone methylation attenuates TGFβ induced EMT characteristics in pancreatic cancer

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3421-3421

2017

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Model‐Based Cellular Kinetic Analysis of Chimeric Antigen Receptor‐T Cells in Humans

Clinical pharmacology and therapeutics, 2021-03, Vol.109 (3), p.716-727

2021

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Chloroquine and Osimertinib Induce Synergic Reduction in Cell Viability through Autophagy/Apoptosis Crosstalk

The FASEB journal, 2019-04, Vol.33 (S1), p.675.13-675.13

2019

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In Vitro Evaluation of Cimetidine Reno‐protective Effects on Cisplatin‐Induced Kidney Injury

The FASEB journal, 2019-04, Vol.33 (S1), p.671.4-671.4

2019

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Identification of Novel and Early Biomarkers for Cisplatin-induced Nephrotoxicity and the Nephroprotective Role of Cimetidine using a Pharmacometabolomic-based Approach Coupled with In Vitro Toxicodynamic Modeling and Simulation

Journal of pharmaceutical sciences, 2024-01, Vol.113 (1), p.268-277

2024

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Clinical Pharmacology Perspective on Development of Adeno‐Associated Virus Vector‐Based Retina Gene Therapy

Clinical pharmacology and therapeutics, 2024-06, Vol.115 (6), p.1212-1232

2024

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Efficacy of Dual HER‐2 and CDK‐4/6 Signaling Blockade at Overcoming Primary HER2 Therapy Resistance in Breast Cancer

The FASEB journal, 2019-04, Vol.33 (S1), p.815.2-815.2

2019

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Multiscale and Translational Quantitative Systems Toxicology, Pharmacokinetic-Toxicodynamic Modeling Analysis for Assessment of Doxorubicin-Induced Cardiotoxicity

The AAPS journal, 2021-01, Vol.23 (1), p.18, Article 18

2021

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Best Practices and Considerations for Clinical Pharmacology and Pharmacometric Aspects for Optimal Development of CAR‐T and TCR‐T Cell Therapies: An Industry Perspective

Clinical pharmacology and therapeutics, 2023-09, Vol.114 (3), p.530-557

2023

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A non-coding RNA axis guides TGF-β-induced gemcitabine chemoresistance

Translational cancer research, 2017-12, Vol.6 (S9), p.S1455-S1457

2017

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An IQ Consortium Perspective on Best Practices for Bioanalytical and Immunogenicity Assessment Aspects of CAR‐T and TCR‐T Cellular Therapies Development

Clinical pharmacology and therapeutics, 2024-02, Vol.115 (2), p.188-200

2024

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Defective hCNT1 transport contributes to gemcitabine chemoresistance in ovarian cancer subtypes: Overcoming transport defects using a nanoparticle approach

Cancer letters, 2015-04, Vol.359 (2), p.233-240

2015

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Introduction to metallic nanoparticles

In vitro to clinical translational pharmacokinetic/pharmacodynamic modeling of doxorubicin (DOX) and dexrazoxane (DEX) interactions: Safety assessment and optimization

Overcoming nucleoside analog chemoresistance of pancreatic cancer: A therapeutic challenge

Inhibition of S-Adenosylmethionine-Dependent Methyltransferase Attenuates TGF beta 1-Induced EMT and Metastasis in Pancreatic Cancer: Putative Roles of miR-663a and miR-4787-5p

In vitro to clinical translation of combinatorial effects of doxorubicin and dexrazoxane in breast cancer: a mechanism-based pharmacokinetic/pharmacodynamic modeling approach

miR-202 Diminishes TGFβ Receptors and Attenuates TGFβ1-Induced EMT in Pancreatic Cancer

SET contributes to the epithelial-mesenchymal transition of pancreatic cancer

A quantitative systems pharmacological approach identified activation of JNK signaling pathway as a promising treatment strategy for refractory HER2 positive breast cancer

Bench‐to‐bedside translation of chimeric antigen receptor (CAR) T cells using a multiscale systems pharmacokinetic‐pharmacodynamic model: A case study with anti‐BCMA CAR‐T

Pharmacodynamic Modeling to Evaluate the Impact of Cimetidine, an OCT2 Inhibitor, on the Anticancer Effects of Cisplatin

Inhibition of S-Adenosylmethionine-Dependent Methyltransferase Attenuates TGFβ1-Induced EMT and Metastasis in Pancreatic Cancer: Putative Roles of miR-663a and miR-4787-5p

Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies

Clinical Pharmacology Considerations for the “Off‐the‐Shelf” Allogeneic Cell Therapies

Abstract 3421: Pharmacological inhibition of histone methylation attenuates TGFβ induced EMT characteristics in pancreatic cancer

Model‐Based Cellular Kinetic Analysis of Chimeric Antigen Receptor‐T Cells in Humans

Chloroquine and Osimertinib Induce Synergic Reduction in Cell Viability through Autophagy/Apoptosis Crosstalk

In Vitro Evaluation of Cimetidine Reno‐protective Effects on Cisplatin‐Induced Kidney Injury

Identification of Novel and Early Biomarkers for Cisplatin-induced Nephrotoxicity and the Nephroprotective Role of Cimetidine using a Pharmacometabolomic-based Approach Coupled with In Vitro Toxicodynamic Modeling and Simulation

Clinical Pharmacology Perspective on Development of Adeno‐Associated Virus Vector‐Based Retina Gene Therapy

Efficacy of Dual HER‐2 and CDK‐4/6 Signaling Blockade at Overcoming Primary HER2 Therapy Resistance in Breast Cancer

Multiscale and Translational Quantitative Systems Toxicology, Pharmacokinetic-Toxicodynamic Modeling Analysis for Assessment of Doxorubicin-Induced Cardiotoxicity

Best Practices and Considerations for Clinical Pharmacology and Pharmacometric Aspects for Optimal Development of CAR‐T and TCR‐T Cell Therapies: An Industry Perspective

A non-coding RNA axis guides TGF-β-induced gemcitabine chemoresistance

An IQ Consortium Perspective on Best Practices for Bioanalytical and Immunogenicity Assessment Aspects of CAR‐T and TCR‐T Cellular Therapies Development

Defective hCNT1 transport contributes to gemcitabine chemoresistance in ovarian cancer subtypes: Overcoming transport defects using a nanoparticle approach

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