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Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues

Cancer research (Chicago, Ill.), 1992-05, Vol.52 (10), p.2835-2840

1992

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Animal cell mutants unable to take up biologically active glycerophospholipids

Journal of lipid research, 1995-09, Vol.36 (9), p.1866-1875

1995

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Inhibition of the signalling enzyme phosphatidylinositol-3-kinase by antitumor ether lipid analogues

Cancer research (Chicago, Ill.), 1993-09, Vol.53 (18), p.4297-4302

1993

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Fate of 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET18-OME) in malignant cells, normal cells, and isolated and perfused rat liver

Drug metabolism and disposition, 1995-01, Vol.23 (1), p.113

1995

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Unidirectional membrane uptake of the ether lipid antineoplastic agent edelfosine by L1210 cells

Biochemical pharmacology, 1993-06, Vol.45 (12), p.2435-2439

1993

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Change in the localization of heat shock protein 27 (HSP 27) in BG-1 human ovarian cancer cells following treatment by the ether lipid ET-18-OCH3

Anticancer research, 1999-01, Vol.19 (1A), p.181

1999

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Effects of antineoplastic ether lipids on model and biological membranes

Biochimica et biophysica acta, 1988-11, Vol.945 (1), p.92-100

1988

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Role of cell cholesterol in modulating antineoplastic ether lipid uptake, membrane effects and cytotoxicity

International journal of cancer, 1990-08, Vol.46 (2), p.341-346

1990

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Correlation of ether lipid content of human leukemia cell lines and their susceptibility to 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine

Cancer research (Chicago, Ill.), 1989-08, Vol.49 (16), p.4441-4445

1989

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Membrane lipid modification and sensitivity of leukemic cells to the thioether lipid analogue BM 41.440

Cancer research (Chicago, Ill.), 1992-11, Vol.52 (22), p.6263-6269

1992

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Synthesis of phosphocholine and quaternary amine ether lipids and evaluation of in vitro antineoplastic activity

Journal of medicinal chemistry, 1993-07, Vol.36 (14), p.2018-2025

1993

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Cytokinetic and morphologic differences in ovarian cancer cells treated with ET-18-OCH3 and the DNA-interacting agent, etoposide

Anticancer research, 1997-05, Vol.17 (3C), p.2159

1997

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Increased ether lipid cytotoxicity by reducing membrane cholesterol content

International journal of cancer, 1991-09, Vol.49 (3), p.409-413

1991

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The effect of culture medium composition on ether lipid cytotoxic activity

Lipids, 1993-03, Vol.28 (3), p.189-192

1993

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Induction of apoptosis in human leukemic cells by the ether lipid 1‐octadecyl‐2‐methyl‐RAC‐glycero‐3‐ phosphocholine. A possible basis for its selective action

International journal of cancer, 1993-01, Vol.53 (1), p.124-130

1993

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Cell kill and cytostasis by ET-18-OCH3 and heat

Anticancer research, 1995-07, Vol.15 (4), p.1333

1995

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Modulation of ATPase activity by cholesterol and synthetic ether lipids in leukemic cells

Biochemical pharmacology, 1992-02, Vol.43 (4), p.803-807

1992

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Membrane damage in leukemic cells induced by ether and ester lipids: An electron microscopic study

Experimental and molecular pathology, 1989-02, Vol.50 (1), p.69-83

1989

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Effects of structural modifications of ether lipids on antiproliferative activity against human glioma cell lines

Anticancer research, 1993-03, Vol.13 (2), p.401

1993

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The induction of apoptosis is a common feature of the cytotoxic action of ether‐linked glycerophospholipids in human leukemic cells

International journal of cancer, 1994-06, Vol.57 (5), p.645-649

1994

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Inhibition of growth factor-dependent inositol phosphate Ca2+ signaling by antitumor ether lipid analogues

Cancer research (Chicago, Ill.), 1990-08, Vol.50 (15), p.4458-4463

1990

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Synthesis of sulfur analogs of alkyl lysophospholipid and neoplastic cell growth inhibitory properties

Journal of medicinal chemistry, 1986-10, Vol.29 (10), p.2114-2117

1986

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Superoxide production by macrophages stimulated in vivo with synthetic ether lipids

Lipids, 1994-04, Vol.29 (4), p.237-242

1994

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Synthesis of quaternary amine ether lipids and evaluation of neoplastic cell growth inhibitory properties

Journal of medicinal chemistry, 1990-06, Vol.33 (6), p.1812-1818

1990

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Tricyclic 2,4-diaminopyrimidines with broad antifolate activity and the ability to inhibit pneumocystis carinii growth in cultured human lung fibroblasts in the presence of leucovorin

Biochemical pharmacology, 1989-08, Vol.38 (16), p.2677-2684

1989

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Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues

Animal cell mutants unable to take up biologically active glycerophospholipids

Inhibition of the signalling enzyme phosphatidylinositol-3-kinase by antitumor ether lipid analogues

Fate of 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET18-OME) in malignant cells, normal cells, and isolated and perfused rat liver

Unidirectional membrane uptake of the ether lipid antineoplastic agent edelfosine by L1210 cells

Change in the localization of heat shock protein 27 (HSP 27) in BG-1 human ovarian cancer cells following treatment by the ether lipid ET-18-OCH3

Effects of antineoplastic ether lipids on model and biological membranes

Role of cell cholesterol in modulating antineoplastic ether lipid uptake, membrane effects and cytotoxicity

Correlation of ether lipid content of human leukemia cell lines and their susceptibility to 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine

Membrane lipid modification and sensitivity of leukemic cells to the thioether lipid analogue BM 41.440

Synthesis of phosphocholine and quaternary amine ether lipids and evaluation of in vitro antineoplastic activity

Cytokinetic and morphologic differences in ovarian cancer cells treated with ET-18-OCH3 and the DNA-interacting agent, etoposide

Increased ether lipid cytotoxicity by reducing membrane cholesterol content

The effect of culture medium composition on ether lipid cytotoxic activity

Induction of apoptosis in human leukemic cells by the ether lipid 1‐octadecyl‐2‐methyl‐RAC‐glycero‐3‐ phosphocholine. A possible basis for its selective action

Cell kill and cytostasis by ET-18-OCH3 and heat

Modulation of ATPase activity by cholesterol and synthetic ether lipids in leukemic cells

Membrane damage in leukemic cells induced by ether and ester lipids: An electron microscopic study

Effects of structural modifications of ether lipids on antiproliferative activity against human glioma cell lines

The induction of apoptosis is a common feature of the cytotoxic action of ether‐linked glycerophospholipids in human leukemic cells

Inhibition of growth factor-dependent inositol phosphate Ca2+ signaling by antitumor ether lipid analogues

Synthesis of sulfur analogs of alkyl lysophospholipid and neoplastic cell growth inhibitory properties

Superoxide production by macrophages stimulated in vivo with synthetic ether lipids

Synthesis of quaternary amine ether lipids and evaluation of neoplastic cell growth inhibitory properties

Tricyclic 2,4-diaminopyrimidines with broad antifolate activity and the ability to inhibit pneumocystis carinii growth in cultured human lung fibroblasts in the presence of leucovorin

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