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Factor VIII Is Synthesized in Human Endothelial Cells, Packaged in Weibel-Palade Bodies and Secreted Bound to ULVWF Strings

PloS one, 2015-10, Vol.10 (10), p.e0140740-e0140740

2015

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Heat-inactivated Factor B inhibits alternative pathway fluid-phase activation and convertase formation on endothelial cell-secreted ultra-large von Willebrand factor strings

Scientific reports, 2023-04, Vol.13 (1), p.5764-5764, Article 5764

2023

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Production and control of coagulation proteins for factor X activation in human endothelial cells and fibroblasts

Scientific reports, 2020-02, Vol.10 (1), p.2005-2005, Article 2005

2020

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TNF Regulates Essential Alternative Complement Pathway Components and Impairs Activation of Protein C in Human Glomerular Endothelial Cells

The Journal of immunology (1950), 2016-01, Vol.196 (2), p.832-845

2016

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Human endothelial cells and fibroblasts express and produce the coagulation proteins necessary for thrombin generation

Scientific reports, 2021-11, Vol.11 (1), p.21852-21852, Article 21852

2021

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N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice

The Journal of clinical investigation, 2011-02, Vol.121 (2), p.593-603

2011

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Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage

Blood, 2009-12, Vol.114 (24), p.5102-5111

2009

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Diagnostic criteria for hematopoietic stem cell transplant-associated microangiopathy: results of a consensus process by an International Working Group

Haematologica (Roma), 2007-01, Vol.92 (1), p.95-100

2007

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ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions

Blood, 2002-12, Vol.100 (12), p.4033-4039

2002

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Thrombotic Microangiopathies

The New England journal of medicine, 2002-08, Vol.347 (8), p.589-600

Moake, Joel L

2002

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Laminin Peptide-Immobilized Hydrogels Modulate Valve Endothelial Cell Hemostatic Regulation

PloS one, 2015-06, Vol.10 (6), p.e0130749-e0130749

2015

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Acquired von Willebrand syndrome associated with left ventricular assist device

Blood, 2016-06, Vol.127 (25), p.3133-3141

2016

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Recent advances in thrombotic thrombocytopenic purpura

Hematology, 2004, Vol.2004 (1), p.407-423

2004

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Regulatory components of the alternative complement pathway in endothelial cell cytoplasm, factor H and factor I, are not packaged in Weibel-Palade bodies

PloS one, 2015-03, Vol.10 (3), p.e0121994-e0121994

2015

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Hemolytic uremic syndrome–associated Shiga toxins promote endothelial-cell secretion and impair ADAMTS13 cleavage of unusually large von Willebrand factor multimers

Blood, 2005-12, Vol.106 (13), p.4199-4209

2005

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P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface

Blood, 2004-03, Vol.103 (6), p.2150-2156

2004

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A new therapeutic strategy for atypical HUS

Blood, 2017-07, Vol.130 (3), p.243-244

Moake, Joel L.

2017

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Ticlopidine- and clopidogrel-associated thrombotic thrombocytopenic purpura (TTP): review of clinical, laboratory, epidemiological, and pharmacovigilance findings (1989–2008)

Kidney international, 2009-02, Vol.75 (112s), p.S20-S24

2009

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Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells

The Journal of biological chemistry, 2018-05, Vol.293 (19), p.7195-7208

2018

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Von Willebrand factor, ADAMTS-13, and thrombotic thrombocytopenic purpura

Seminars in hematology, 2004, Vol.41 (1), p.4-14

Moake, Joel L

2004

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ADAMTS-13 Metalloprotease Interacts with the Endothelial Cell-derived Ultra-large von Willebrand Factor

The Journal of biological chemistry, 2003-08, Vol.278 (32), p.29633-29639

2003

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Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions

Blood, 2005-12, Vol.106 (13), p.4139-4145

2005

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THROMBOTIC THROMBOCYTOPENIC PURPURA: The Systemic Clumping "Plague"

Annual review of medicine, 2002-01, Vol.53 (1), p.75-88

Moake, Joel L

2002

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Complement Component C3 Binds to the A3 Domain of von Willebrand Factor

TH open : companion journal to thrombosis and haemostasis, 2018-07, Vol.2 (3), p.e338-e345

2018

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Treatment of refractory thrombotic thrombocytopenic purpura with N-acetylcysteine: a case report

Transfusion (Philadelphia, Pa.), 2014-05, Vol.54 (5), p.1221-1224

2014

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Factor VIII Is Synthesized in Human Endothelial Cells, Packaged in Weibel-Palade Bodies and Secreted Bound to ULVWF Strings

Heat-inactivated Factor B inhibits alternative pathway fluid-phase activation and convertase formation on endothelial cell-secreted ultra-large von Willebrand factor strings

Production and control of coagulation proteins for factor X activation in human endothelial cells and fibroblasts

TNF Regulates Essential Alternative Complement Pathway Components and Impairs Activation of Protein C in Human Glomerular Endothelial Cells

Human endothelial cells and fibroblasts express and produce the coagulation proteins necessary for thrombin generation

N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice

Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage

Diagnostic criteria for hematopoietic stem cell transplant-associated microangiopathy: results of a consensus process by an International Working Group

ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions

Thrombotic Microangiopathies

Laminin Peptide-Immobilized Hydrogels Modulate Valve Endothelial Cell Hemostatic Regulation

Acquired von Willebrand syndrome associated with left ventricular assist device

Recent advances in thrombotic thrombocytopenic purpura

Regulatory components of the alternative complement pathway in endothelial cell cytoplasm, factor H and factor I, are not packaged in Weibel-Palade bodies

Hemolytic uremic syndrome–associated Shiga toxins promote endothelial-cell secretion and impair ADAMTS13 cleavage of unusually large von Willebrand factor multimers

P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface

A new therapeutic strategy for atypical HUS

Ticlopidine- and clopidogrel-associated thrombotic thrombocytopenic purpura (TTP): review of clinical, laboratory, epidemiological, and pharmacovigilance findings (1989–2008)

Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells

Von Willebrand factor, ADAMTS-13, and thrombotic thrombocytopenic purpura

ADAMTS-13 Metalloprotease Interacts with the Endothelial Cell-derived Ultra-large von Willebrand Factor

Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions

THROMBOTIC THROMBOCYTOPENIC PURPURA: The Systemic Clumping "Plague"

Complement Component C3 Binds to the A3 Domain of von Willebrand Factor

Treatment of refractory thrombotic thrombocytopenic purpura with N-acetylcysteine: a case report

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