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Evaluation of the Biological Effect of Non-UV-Activated Bergapten on Selected Human Tumor Cells and the Insight into the Molecular Mechanism of Its Action
International journal of molecular sciences, 2023-10, Vol.24 (21), p.15555
2023
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Alpha Ketoglutarate Downregulates the Neutral Endopeptidase and Enhances the Growth Inhibitory Activity of Thiorphan in Highly Aggressive Osteosarcoma Cells
Molecules (Basel, Switzerland), 2022-12, Vol.28 (1), p.97
2022
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New Borane-Protected Derivatives of α-Aminophosphonous Acid as Anti-Osteosarcoma Agents: ADME Analysis and Molecular Modeling, In Vitro Studies on Anti-Cancer Activities, and NEP Inhibition as a Possible Mechanism of Anti-Proliferative Activity
International journal of molecular sciences, 2022-06, Vol.23 (12), p.6716
2022
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Betulin Promotes Differentiation of Human Osteoblasts In Vitro and Exerts an Osteoinductive Effect on the hFOB 1.19 Cell Line Through Activation of JNK, ERK1/2, and mTOR Kinases
Molecules (Basel, Switzerland), 2019-07, Vol.24 (14), p.2637
2019
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Discovery of New 3,3-Diethylazetidine-2,4-dione Based Thiazoles as Nanomolar Human Neutrophil Elastase Inhibitors with Broad-Spectrum Antiproliferative Activity
International journal of molecular sciences, 2022-07, Vol.23 (14), p.7566
2022
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Alpha Ketoglutarate Exerts In Vitro Anti-Osteosarcoma Effects through Inhibition of Cell Proliferation, Induction of Apoptosis via the JNK and Caspase 9-Dependent Mechanism, and Suppression of TGF-β and VEGF Production and Metastatic Potential of Cells
International journal of molecular sciences, 2020-12, Vol.21 (24), p.9406
2020
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Tropinone-Derived Alkaloids as Potent Anticancer Agents: Synthesis, Tyrosinase Inhibition, Mechanism of Action, DFT Calculation, and Molecular Docking Studies
International journal of molecular sciences, 2020-11, Vol.21 (23), p.9050
2020
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Xanthohumol Impairs the PMA-Driven Invasive Behaviour of Lung Cancer Cell Line A549 and Exerts Anti-EMT Action
Cells (Basel, Switzerland), 2021-06, Vol.10 (6), p.1484
2021
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Pseudomonas aeruginosa exotoxin A induces apoptosis in Galleria mellonella hemocytes
Journal of invertebrate pathology, 2023-03, Vol.197, p.107884-107884, Article 107884
2023
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Xanthohumol exhibits anti-myeloma activity in vitro through inhibition of cell proliferation, induction of apoptosis via the ERK and JNK-dependent mechanism, and suppression of sIL-6R and VEGF production
Biochimica et biophysica acta. General subjects, 2019-11, Vol.1863 (11), p.129408-129408, Article 129408
2019
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Alpha ketoglutarate exerts a pro-osteogenic effect in osteoblast cell lines through activation of JNK and mTOR/S6K1/S6 signaling pathways
Toxicology and applied pharmacology, 2019-07, Vol.374, p.53-64
2019
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Thalidomide derivatives as nanomolar human neutrophil elastase inhibitors: Rational design, synthesis, antiproliferative activity and mechanism of action
Bioorganic chemistry, 2023-09, Vol.138, p.106608-106608, Article 106608
2023
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Neutral endopeptidase (NEP) inhibitors – thiorphan, sialorphin, and its derivatives exert anti-proliferative activity towards colorectal cancer cells in vitro
Chemico-biological interactions, 2019-07, Vol.307, p.105-115
2019
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Neutral endopeptidase (NEP) is differentially involved in biological activities and cell signaling of colon cancer cell lines derived from various stages of tumor development
Tumor biology, 2016-10, Vol.37 (10), p.13355-13368
2016
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