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Identification and characterization of a novel botulinum neurotoxin

Nature communications, 2017-08, Vol.8 (1), p.14130-14130, Article 14130

2017

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Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium

Cell host & microbe, 2018-02, Vol.23 (2), p.169-176.e6

2018

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Genetically encoded fluorescent indicators for imaging intracellular potassium ion concentration

Communications biology, 2019-01, Vol.2 (1), p.18-18, Article 18

2019

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Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy

PLoS biology, 2020-03, Vol.18 (3), p.e3000618

2020

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Knockin mouse models demonstrate differential contributions of synaptotagmin-1 and -2 as receptors for botulinum neurotoxins

PLoS pathogens, 2021-10, Vol.17 (10), p.e1009994-e1009994

2021

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Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells

Nature microbiology, 2019-10, Vol.4 (10), p.1760-1769

2019

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Characterization of Serotype CD Mosaic Botulinum Neurotoxin in Comparison with Serotype C and A

Toxins, 2023-02, Vol.15 (2), p.123

2023

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Host-cell specificity and transcytosis of nontoxic nonhemagglutinin protein of botulinum neurotoxin serotype D

FEMS microbiology letters, 2014-08, Vol.357 (2), p.115-122

2014

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Delivery of single-domain antibodies into neurons using a chimeric toxin–based platform is therapeutic in mouse models of botulism

Science translational medicine, 2021-01, Vol.13 (575)

2021

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"Non-Toxic" Proteins of the Botulinum Toxin Complex Exert In-vivo Toxicity

Scientific reports, 2016-08, Vol.6 (1), p.31043-31043, Article 31043

2016

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Transport of the botulinum neurotoxin–associating protein, nontoxic nonhemagglutinin, across the rat small intestinal epithelial cell monolayer

FEMS microbiology letters, 2013-09, Vol.346 (1), p.73-80

2013

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Massively parallel de novo protein design for targeted therapeutics

Nature (London), 2017-10, Vol.550 (7674), p.74-79

2017

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Species-specific gene duplication in Clostridia produces variations of cholesterol-dependent cytolysin with different cytotoxicity

Biochemical and biophysical research communications, 2022-12, Vol.637, p.240-246

2022

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Complete subunit structure of serotype C and D botulinum progenitor toxin complex induces vacuolation in the specific epithelial cell line

Biochemical and biophysical research communications, 2022-12, Vol.632, p.55-61

2022

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Small-angle X-ray scattering reveals structural dynamics of the botulinum neurotoxin associating protein, nontoxic nonhemagglutinin

Biochemical and biophysical research communications, 2012-08, Vol.425 (2), p.256-260

2012

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Sugar-induced conformational change found in the HA-33/HA-17 trimer of the botulinum toxin complex

Biochemical and biophysical research communications, 2013-08, Vol.438 (3), p.483-487

2013

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Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes

Data in brief, 2019-08, Vol.25, p.104193, Article 104193

2019

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Toxic and nontoxic components of botulinum neurotoxin complex are evolved from a common ancestral zinc protein

Biochemical and biophysical research communications, 2012-03, Vol.419 (3), p.500-504

2012

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Identification of the interaction region between hemagglutinin components of the botulinum toxin complex

International journal of biological macromolecules, 2014-04, Vol.65, p.284-288

2014

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Covalent Modifiers of Botulinum Neurotoxin Counteract Toxin Persistence

ACS chemical biology, 2019-01, Vol.14 (1), p.76-87

2019

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Botulinum Toxin Complex Increases Paracellular Permeability in Intestinal Epithelial Cells via Activation of p38 Mitogen-Activated Protein Kinase

Journal of Veterinary Medical Science, 2013, Vol.75(12), pp.1637-1642

2013

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Crystallization and preliminary X-ray analysis of a novel haemagglutinin component of the toxin complex of serotype C Clostridium botulinum

Acta crystallographica. Section F, Structural biology communications, 2014-03, Vol.70 (3), p.370-373

2014

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食感と血のような味質を改善した「蝦夷鹿ソーセージ」の開発

日本食品科学工学会誌, 2023/01/15, Vol.70(1), pp.25-31

2023

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小豆餡の嗜好性と水分および糖度との関係

日本食品科学工学会誌, 2022/10/15, Vol.69(10), pp.473-480

2022

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Functional Deimmunization of Botulinum Neurotoxin Protease Domain via Computationally Driven Library Design and Ultrahigh-Throughput Screening

ACS synthetic biology, 2023-01, Vol.12 (1), p.153-163

2023

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Identification and characterization of a novel botulinum neurotoxin

Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium

Genetically encoded fluorescent indicators for imaging intracellular potassium ion concentration

Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy

Knockin mouse models demonstrate differential contributions of synaptotagmin-1 and -2 as receptors for botulinum neurotoxins

Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells

Characterization of Serotype CD Mosaic Botulinum Neurotoxin in Comparison with Serotype C and A

Host-cell specificity and transcytosis of nontoxic nonhemagglutinin protein of botulinum neurotoxin serotype D

Delivery of single-domain antibodies into neurons using a chimeric toxin–based platform is therapeutic in mouse models of botulism

"Non-Toxic" Proteins of the Botulinum Toxin Complex Exert In-vivo Toxicity

Transport of the botulinum neurotoxin–associating protein, nontoxic nonhemagglutinin, across the rat small intestinal epithelial cell monolayer

Massively parallel de novo protein design for targeted therapeutics

Species-specific gene duplication in Clostridia produces variations of cholesterol-dependent cytolysin with different cytotoxicity

Complete subunit structure of serotype C and D botulinum progenitor toxin complex induces vacuolation in the specific epithelial cell line

Small-angle X-ray scattering reveals structural dynamics of the botulinum neurotoxin associating protein, nontoxic nonhemagglutinin

Sugar-induced conformational change found in the HA-33/HA-17 trimer of the botulinum toxin complex

Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes

Toxic and nontoxic components of botulinum neurotoxin complex are evolved from a common ancestral zinc protein

Identification of the interaction region between hemagglutinin components of the botulinum toxin complex

Covalent Modifiers of Botulinum Neurotoxin Counteract Toxin Persistence

Botulinum Toxin Complex Increases Paracellular Permeability in Intestinal Epithelial Cells via Activation of p38 Mitogen-Activated Protein Kinase

Crystallization and preliminary X-ray analysis of a novel haemagglutinin component of the toxin complex of serotype C Clostridium botulinum

食感と血のような味質を改善した「蝦夷鹿ソーセージ」の開発

小豆餡の嗜好性と水分および糖度との関係

Functional Deimmunization of Botulinum Neurotoxin Protease Domain via Computationally Driven Library Design and Ultrahigh-Throughput Screening

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