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Michael additions in polyketide biosynthesis

Natural product reports, 2019-03, Vol.36 (3), p.531-547

Miyanaga, Akimasa

2019

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Structure and function of polyketide biosynthetic enzymes: various strategies for production of structurally diverse polyketides

Bioscience, Biotechnology, and Biochemistry, 2017-12, Vol.81 (12), p.2227-2236

Miyanaga, Akimasa

2017

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Recent advances in the structural analysis of adenylation domains in natural product biosynthesis

Current opinion in chemical biology, 2022-12, Vol.71, p.102212-102212, Article 102212

2022

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Protein-protein interactions in polyketide synthase-nonribosomal peptide synthetase hybrid assembly lines

Natural product reports, 2018-11, Vol.35 (11), p.1185-129

2018

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Substrate Specificity of Chondroitinase ABC-I Based on Analyses of Biochemical Reactions and Crystal Structure

Trends in glycoscience and glycotechnology, 2023-11, Vol.35 (208), p.E94-E99, Article 2319.1E

2023

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Biochemical and crystallographic assessments of the effect of 4,6‐O‐disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity

The FEBS journal, 2023-05, Vol.290 (9), p.2379-2393

2023

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Structural basis of the nonribosomal codes for nonproteinogenic amino acid selective adenylation enzymes in the biosynthesis of natural products

Journal of industrial microbiology & biotechnology, 2019-03, Vol.46 (3-4), p.515-536

2019

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Protein‐Protein Recognition Involved in the Intermodular Transacylation Reaction in Modular Polyketide Synthase in the Biosynthesis of Vicenistatin

Chembiochem : a European journal of chemical biology, 2022-07, Vol.23 (14), p.e202200200-n/a

2022

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Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (7), p.1802-1807

2016

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Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement

Nature (London), 2013-11, Vol.503 (7477), p.552-556

2013

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Structural Characterization of Complex of Adenylation Domain and Carrier Protein by Using Pantetheine Cross-Linking Probe

ACS chemical biology, 2020-07, Vol.15 (7), p.1808-1812

2020

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Structural Basis of Protein–Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis

Journal of the American Chemical Society, 2018-06, Vol.140 (25), p.7970-7978

2018

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Functional and Structural Analysis of a β-Glucosidase Involved in β-1,2-Glucan Metabolism in Listeria innocua

PloS one, 2016-02, Vol.11 (2), p.e0148870-e0148870

2016

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Stereochemistry in the Reaction of the myo-Inositol Phosphate Synthase Ortholog Ari2 during Aristeromycin Biosynthesis

Biochemistry (Easton), 2019-12, Vol.58 (51), p.5112-5116

2019

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Unique Initiation and Termination Mechanisms Involved in the Biosynthesis of a Hybrid Polyketide-Nonribosomal Peptide Lyngbyapeptin B Produced by the Marine Cyanobacterium Moorena bouillonii

ACS chemical biology, 2023-04, Vol.18 (4), p.875-883

2023

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Stepwise Post‐glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis

Chembiochem : a European journal of chemical biology, 2021-05, Vol.22 (9), p.1668-1675

2021

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Generation of incednine derivatives by mutasynthesis

Journal of antibiotics, 2020-11, Vol.73 (11), p.794-797

2020

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Recent advances in the structural biology of modular polyketide synthases and nonribosomal peptide synthetases

Current opinion in chemical biology, 2022-12, Vol.71, p.102223-102223, Article 102223

2022

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One-pot enzymatic synthesis of 2-deoxy-scyllo-inosose from d-glucose and polyphosphate

Bioscience, biotechnology, and biochemistry, 2021-01, Vol.85 (1), p.108-114

2021

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Substrate Recognition by a Dual‐Function P450 Monooxygenase GfsF Involved in FD‐891 Biosynthesis

Chembiochem : a European journal of chemical biology, 2017-11, Vol.18 (21), p.2179-2187

2017

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Genome Mining of the Hitachimycin Biosynthetic Gene Cluster: Involvement of a Phenylalanine-2,3-aminomutase in Biosynthesis

Chembiochem : a European journal of chemical biology, 2015-04, Vol.16 (6), p.909-914

2015

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Direct transfer of starter substrates from type I fatty acid synthase to type III polyketide synthases in phenolic lipid synthesis

Proceedings of the National Academy of Sciences - PNAS, 2008-01, Vol.105 (3), p.871-876

2008

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Structural Basis for Cyclization Specificity of Two Azotobacter Type III Polyketide Synthases

The Journal of biological chemistry, 2013-11, Vol.288 (47), p.34146-34157

2013

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Functional and structural characterization of IdnL7, an adenylation enzyme involved in incednine biosynthesis

Acta crystallographica. Section F, Structural biology communications, 2019-04, Vol.75 (4), p.299-306

2019

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Crystal Structure of Cobalt-Containing Nitrile Hydratase

Biochemical and biophysical research communications, 2001-11, Vol.288 (5), p.1169-1174

2001

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Michael additions in polyketide biosynthesis

Structure and function of polyketide biosynthetic enzymes: various strategies for production of structurally diverse polyketides

Recent advances in the structural analysis of adenylation domains in natural product biosynthesis

Protein-protein interactions in polyketide synthase-nonribosomal peptide synthetase hybrid assembly lines

Substrate Specificity of Chondroitinase ABC-I Based on Analyses of Biochemical Reactions and Crystal Structure

Biochemical and crystallographic assessments of the effect of 4,6‐O‐disulfated disaccharide moieties in chondroitin sulfate E on chondroitinase ABC I activity

Structural basis of the nonribosomal codes for nonproteinogenic amino acid selective adenylation enzymes in the biosynthesis of natural products

Protein‐Protein Recognition Involved in the Intermodular Transacylation Reaction in Modular Polyketide Synthase in the Biosynthesis of Vicenistatin

Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis

Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement

Structural Characterization of Complex of Adenylation Domain and Carrier Protein by Using Pantetheine Cross-Linking Probe

Structural Basis of Protein–Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis

Functional and Structural Analysis of a β-Glucosidase Involved in β-1,2-Glucan Metabolism in Listeria innocua

Stereochemistry in the Reaction of the myo-Inositol Phosphate Synthase Ortholog Ari2 during Aristeromycin Biosynthesis

Unique Initiation and Termination Mechanisms Involved in the Biosynthesis of a Hybrid Polyketide-Nonribosomal Peptide Lyngbyapeptin B Produced by the Marine Cyanobacterium Moorena bouillonii

Stepwise Post‐glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis

Generation of incednine derivatives by mutasynthesis

Recent advances in the structural biology of modular polyketide synthases and nonribosomal peptide synthetases

One-pot enzymatic synthesis of 2-deoxy-scyllo-inosose from d-glucose and polyphosphate

Substrate Recognition by a Dual‐Function P450 Monooxygenase GfsF Involved in FD‐891 Biosynthesis

Genome Mining of the Hitachimycin Biosynthetic Gene Cluster: Involvement of a Phenylalanine-2,3-aminomutase in Biosynthesis

Direct transfer of starter substrates from type I fatty acid synthase to type III polyketide synthases in phenolic lipid synthesis

Structural Basis for Cyclization Specificity of Two Azotobacter Type III Polyketide Synthases

Functional and structural characterization of IdnL7, an adenylation enzyme involved in incednine biosynthesis

Crystal Structure of Cobalt-Containing Nitrile Hydratase

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