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Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational drug on ulcerative colitis using human colonic organoids

Journal of gastroenterology, 2019-07, Vol.54 (7), p.608-620

2019

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KAG-308, a newly-identified EP4-selective agonist shows efficacy for treating ulcerative colitis and can bring about lower risk of colorectal carcinogenesis by oral administration

European journal of pharmacology, 2015-05, Vol.754, p.179-189

2015

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Oral administration of EP4-selective agonist KAG-308 suppresses mouse knee osteoarthritis development through reduction of chondrocyte hypertrophy and TNF secretion

Scientific reports, 2019-12, Vol.9 (1), p.20329-13, Article 20329

2019

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A Bispecific, Tetravalent Antibody Targeting Inflammatory and Pruritogenic Pathways in Atopic Dermatitis

JID innovations, 2024-03, Vol.4 (2), p.100258-100258, Article 100258

2024

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Preventive Effects of a Novel Orally-Active EP4-Selective Agonist, KAG-308, in Gastrointestinal Mucosal Injuries

Digestive diseases and sciences, 2022-05, Vol.60 (9), p.2565

2022

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KIF1Bβ2, Capable of Interacting with CHP, Is Localized to Synaptic Vesicles

Journal of biochemistry (Tokyo), 2002-09, Vol.132 (3), p.483-491

2002

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A Serine/Threonine Kinase Which Causes Apoptosis-Like Cell Death Interacts with a Calcineurin B-Like Protein Capable of Binding Na+/H+ Exchanger

Journal of biochemistry (Tokyo), 2001-08, Vol.130 (2), p.217-225

2001

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Kag-308, a Novel Orally Active EP4 Agonist, Ameliorates Mucosal Injury on Endoscopic Examination in a Chronic Colitis Model

Gastroenterology (New York, N.Y. 1943), 2011, Vol.140 (5), p.S-517-S-517

2011

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Effect of inhaled KP-496, a novel dual antagonist of the cysteinyl leukotriene and thromboxane A2 receptors, on a bleomycin-induced pulmonary fibrosis model in mice

Pulmonary pharmacology & therapeutics, 2010-10, Vol.23 (5), p.425-431

2010

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Effect of inhaled KP-496, a novel dual antagonist of the cysteinyl leukotriene and thromboxane A 2 receptors, on a bleomycin-induced pulmonary fibrosis model in mice

Pulmonary pharmacology & therapeutics, 2010, Vol.23 (5), p.425-431

2010

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KIF1Bbeta2, capable of interacting with CHP, is localized to synaptic vesicles

Journal of biochemistry (Tokyo), 2002-09, Vol.132 (3), p.483-491

2002

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KIF1B 2, Capable of Interacting with CHP, Is Localized to Synaptic Vesicles

Journal of biochemistry (Tokyo), 2002-09, Vol.132 (3), p.483-491

2002

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Efficacy and safety of second-line cabozantinib after immuno-oncology combination therapy for advanced renal cell carcinoma: Japanese multicenter retrospective study

Scientific reports, 2023-11, Vol.13 (1), p.20629-20629, Article 20629

2023

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Practical Synthetic Method for the Preparation of Pyrone Diesters: An Efficient Synthetic Route for the Synthesis of Dolutegravir Sodium

Organic process research & development, 2019-04, Vol.23 (4), p.565-570

2019

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Intraoperative Integrated Diagnostic System for Malignant Central Nervous System Tumors

Clinical cancer research, 2024-01, Vol.30 (1), p.116-126

2024

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Atriofascicular Mahaim with Ebstein anomaly: A case report

Journal of arrhythmia, 2017-10, Vol.33 (5), p.508-510

2017

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Importance of a Collaboration Agreement in the Management of Physician-Staffed Helicopters

Air medical journal, 2022-01, Vol.41 (1), p.52-56

2022

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Current status and problems of driving in elderly with cognitive decline in Okayama

KAWASAKI MEDICAL JOURNAL, 2023, Vol.49, p.69-74

2023

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Genetic Spectrum of EYS-associated Retinal Disease in a Large Japanese Cohort: Identification of Disease-associated Variants with Relatively High Allele Frequency

Scientific reports, 2020-03, Vol.10 (1), p.5497-5497, Article 5497

2020

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Clinical and Genetic Characteristics of 18 Patients from 13 Japanese Families with CRX-associated retinal disorder: Identification of Genotype-phenotype Association

Scientific reports, 2020-06, Vol.10 (1), p.9531-9531, Article 9531

2020

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Unusual type of scleromyxedema with multiple subcutaneous nodules, IgM-λ paraproteinemia, and scleroderma-like microangiopathy

Journal of scleroderma and related disorders, 2021-06, Vol.6 (2), p.220-224

2021

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Spontaneous closure of ventricular septal defects followed up from <3 months of age

Pediatrics international, 2004-04, Vol.46 (2), p.135-140

2004

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Utility of plasma D-dimer for diagnosis of venous thromboembolism after hepatectomy

World journal of clinical cases, 2024-01, Vol.12 (2), p.276-284

2024

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Nifekalant Hydrochloride and Amiodarone Hydrochloride Result in Similar Improvements for 24-Hour Survival in Cardiopulmonary Arrest Patients: The SOS-KANTO 2012 Study

Journal of cardiovascular pharmacology, 2015-12, Vol.66 (6), p.600-609

2015

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Does Antiarrhythmic Drug During Cardiopulmonary Resuscitation Improve the One-month Survival: The SOS-KANTO 2012 Study

Journal of cardiovascular pharmacology, 2016-07, Vol.68 (1), p.58-66

2016

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Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational drug on ulcerative colitis using human colonic organoids

KAG-308, a newly-identified EP4-selective agonist shows efficacy for treating ulcerative colitis and can bring about lower risk of colorectal carcinogenesis by oral administration

Oral administration of EP4-selective agonist KAG-308 suppresses mouse knee osteoarthritis development through reduction of chondrocyte hypertrophy and TNF secretion

A Bispecific, Tetravalent Antibody Targeting Inflammatory and Pruritogenic Pathways in Atopic Dermatitis

Preventive Effects of a Novel Orally-Active EP4-Selective Agonist, KAG-308, in Gastrointestinal Mucosal Injuries

KIF1Bβ2, Capable of Interacting with CHP, Is Localized to Synaptic Vesicles

A Serine/Threonine Kinase Which Causes Apoptosis-Like Cell Death Interacts with a Calcineurin B-Like Protein Capable of Binding Na+/H+ Exchanger

Kag-308, a Novel Orally Active EP4 Agonist, Ameliorates Mucosal Injury on Endoscopic Examination in a Chronic Colitis Model

Effect of inhaled KP-496, a novel dual antagonist of the cysteinyl leukotriene and thromboxane A2 receptors, on a bleomycin-induced pulmonary fibrosis model in mice

Effect of inhaled KP-496, a novel dual antagonist of the cysteinyl leukotriene and thromboxane A 2 receptors, on a bleomycin-induced pulmonary fibrosis model in mice

KIF1Bbeta2, capable of interacting with CHP, is localized to synaptic vesicles

KIF1B 2, Capable of Interacting with CHP, Is Localized to Synaptic Vesicles

Efficacy and safety of second-line cabozantinib after immuno-oncology combination therapy for advanced renal cell carcinoma: Japanese multicenter retrospective study

Practical Synthetic Method for the Preparation of Pyrone Diesters: An Efficient Synthetic Route for the Synthesis of Dolutegravir Sodium

Intraoperative Integrated Diagnostic System for Malignant Central Nervous System Tumors

Atriofascicular Mahaim with Ebstein anomaly: A case report

Importance of a Collaboration Agreement in the Management of Physician-Staffed Helicopters

Current status and problems of driving in elderly with cognitive decline in Okayama

Genetic Spectrum of EYS-associated Retinal Disease in a Large Japanese Cohort: Identification of Disease-associated Variants with Relatively High Allele Frequency

Clinical and Genetic Characteristics of 18 Patients from 13 Japanese Families with CRX-associated retinal disorder: Identification of Genotype-phenotype Association

Unusual type of scleromyxedema with multiple subcutaneous nodules, IgM-λ paraproteinemia, and scleroderma-like microangiopathy

Spontaneous closure of ventricular septal defects followed up from <3 months of age

Utility of plasma D-dimer for diagnosis of venous thromboembolism after hepatectomy

Nifekalant Hydrochloride and Amiodarone Hydrochloride Result in Similar Improvements for 24-Hour Survival in Cardiopulmonary Arrest Patients: The SOS-KANTO 2012 Study

Does Antiarrhythmic Drug During Cardiopulmonary Resuscitation Improve the One-month Survival: The SOS-KANTO 2012 Study

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