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Effect of Praliciguat on Peak Rate of Oxygen Consumption in Patients With Heart Failure With Preserved Ejection Fraction: The CAPACITY HFpEF Randomized Clinical Trial

JAMA : the journal of the American Medical Association, 2020-10, Vol.324 (15), p.1522

2020

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Long-term efficacy and safety of mipomersen in patients with familial hypercholesterolaemia: 2-year interim results of an open-label extension

European heart journal, 2015-03, Vol.36 (9), p.566-575

2015

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Efficacy and safety of setmelanotide, a melanocortin-4 receptor agonist, in patients with Bardet-Biedl syndrome and Alström syndrome: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial with an open-label period

The lancet. Diabetes & endocrinology, 2022-12, Vol.10 (12), p.859-868

2022

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IW-3718 Reduces Heartburn Severity in Patients With Refractory Gastroesophageal Reflux Disease in a Randomized Trial

Gastroenterology (New York, N.Y. 1943), 2020-06, Vol.158 (8), p.2093-2103

2020

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Interview-Based Patient- and Caregiver-Reported Experiences of Hunger and Improved Quality of Life with Setmelanotide Treatment in Bardet-Biedl Syndrome

Advances in therapy, 2023-05, Vol.40 (5), p.2394-2411

2023

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Rationale and design for a multicenter, randomized, double-blind, placebo-controlled, phase 2 study evaluating the safety and efficacy of the soluble guanylate cyclase stimulator praliciguat over 12 weeks in patients with heart failure with preserved ejection fraction (CAPACITY HFpEF)

The American heart journal, 2020-04, Vol.222, p.183-190

2020

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The Mode Selection Trial (MOST) in sinus node dysfunction: Design, rationale, and baseline characteristics of the first 1000 patients

The American heart journal, 2000-10, Vol.140 (4), p.541-551

2000

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Complex effects of inhibiting hepatic apolipoprotein B100 synthesis in humans

Science translational medicine, 2016-01, Vol.8 (323), p.323ra12

2016

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Evaluation of right atrial and biatrial temporary pacing for the prevention of atrial fibrillation after coronary artery bypass surgery

Journal of the American College of Cardiology, 1999-06, Vol.33 (7), p.1981-1988

1999

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No effect on QT intervals of mipomersen, a 2′-O-methoxyethyl modified antisense oligonucleotide targeting ApoB-100 mRNA, in a phase I dose escalation placebo-controlled study, and confirmed by a thorough QT (tQT) study, in healthy subjects

European journal of clinical pharmacology, 2016-03, Vol.72 (3), p.267-275

2016

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SAT101 - A randomized, double-blind study to evaluate the safety and tolerability of KB174, a novel synthetic glycan, in patients with well-compensated cirrhosis

Journal of hepatology, 2020-08, Vol.73, p.S699-S699

2020

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A randomized, double-blind study to evaluate the safety and tolerability of KB174, a novel synthetic glycan, in patients with well-compensated cirrhosis

Journal of hepatology, 2020-08, Vol.73, p.S699

2020

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SAT143 - Microbiome metabolic therapies reduce microbiota-associated ammonia in ex vivo fecal samples from healthy subjects and patients with minimal hepatic encephalopathy and demonstrate improved tolerability over lactulose in a clinical study

Journal of hepatology, 2020-08, Vol.73, p.S721-S722

2020

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Microbiome metabolic therapies reduce microbiota-associated ammonia in ex vivo fecal samples from healthy subjects and patients with minimal hepatic encephalopathy and demonstrate improved tolerability over lactulose in a clinical study

Journal of hepatology, 2020-08, Vol.73, p.S721-S722

2020

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Tu1711 A RANDOMIZED, DOUBLE-BLIND STUDY TO EVALUATE THE SAFETY AND TOLERABILITY OF KB174, A NOVEL SYNTHETIC GLYCAN, IN PATIENTS WITH WELL-COMPENSATED CIRRHOSIS

Gastroenterology (New York, N.Y. 1943), 2020-05, Vol.158 (6), p.S-1465-S-1465

2020

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Long-Term Safety and Efficacy of Mipomersen in Patients with Familial Hypercholesterolemia Uncontrolled by Maximally Tolerated Lipid Lowering Therapy

Journal of clinical lipidology, 2012-05, Vol.6 (3), p.291-291

2012

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Migration and Right Atrial Perforation of an Accufix Atrial Lead Retention Wire Following Partial Lead Removal During Myomectomy

Chest, 1998-08, Vol.114 (2), p.637-639

1998

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12 – Impact of Iw-3718, a Novel Gastric-Retentive Bile Acid Sequestrant, on a Spectrum of Gerd Symptoms in Patients with Persistent Gerd Receiving Ppis – Results from a Double-Blind, Placebo-Controlled Study

Gastroenterology (New York, N.Y. 1943), 2019-05, Vol.156 (6), p.S-5-S-5

2019

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Multiple-Ascending-Dose Study of the Soluble Guanylate Cyclase Stimulator, IW-1701, in Healthy Subjects

Blood, 2017-12, Vol.130, p.3533-3533

2017

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Safety and Efficacy of the Soluble Guanylate Cyclase Stimulator Praliciguat in Patients with Heart Failure with Preserved Ejection Fraction (Capacity HFpEF): A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial

Journal of cardiac failure, 2020-10, Vol.26 (10), p.S8-S8

2020

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Effectiveness of bi-atrial pacing for reducing atrial fibrillation after coronary artery bypass graft surgery

Journal of interventional cardiac electrophysiology, 2001-09, Vol.5 (3), p.275-283

2001

Volltextzugriff (PDF)

Use of the Saline Infusion Electrode Catheter for Improved Energy Delivery and Increased Lesion Size in Radiofrequency Catheter Ablation

Pacing and clinical electrophysiology, 1995-05, Vol.18 (5), p.1022-1027

1995

Volltextzugriff (PDF)

Case report: anterograde 2:1 and retrograde 3:2 Wenckebach block during atrioventricular nodal tachycardia: controversies of the upper and lower common pathways

Journal of interventional cardiac electrophysiology, 2000-12, Vol.4 (4), p.605-610

2000

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Cardiovascular complications after radiofrequency catheter ablation of supraventricular tachyarrhythmias

The American journal of cardiology, 1994-09, Vol.74 (6), p.615-617

1994

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Concomitant Reentrant Tachycardias from Concealed Accessory Atrioventricular Bypass Tract and Atrioventricular Nodal Reentry in a Patient with Williams Syndrome

Cardiology, 1999-01, Vol.91 (4), p.264-267

1999

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Effect of Praliciguat on Peak Rate of Oxygen Consumption in Patients With Heart Failure With Preserved Ejection Fraction: The CAPACITY HFpEF Randomized Clinical Trial

Long-term efficacy and safety of mipomersen in patients with familial hypercholesterolaemia: 2-year interim results of an open-label extension

Efficacy and safety of setmelanotide, a melanocortin-4 receptor agonist, in patients with Bardet-Biedl syndrome and Alström syndrome: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial with an open-label period

IW-3718 Reduces Heartburn Severity in Patients With Refractory Gastroesophageal Reflux Disease in a Randomized Trial

Interview-Based Patient- and Caregiver-Reported Experiences of Hunger and Improved Quality of Life with Setmelanotide Treatment in Bardet-Biedl Syndrome

Rationale and design for a multicenter, randomized, double-blind, placebo-controlled, phase 2 study evaluating the safety and efficacy of the soluble guanylate cyclase stimulator praliciguat over 12 weeks in patients with heart failure with preserved ejection fraction (CAPACITY HFpEF)

The Mode Selection Trial (MOST) in sinus node dysfunction: Design, rationale, and baseline characteristics of the first 1000 patients

Complex effects of inhibiting hepatic apolipoprotein B100 synthesis in humans

Evaluation of right atrial and biatrial temporary pacing for the prevention of atrial fibrillation after coronary artery bypass surgery

No effect on QT intervals of mipomersen, a 2′-O-methoxyethyl modified antisense oligonucleotide targeting ApoB-100 mRNA, in a phase I dose escalation placebo-controlled study, and confirmed by a thorough QT (tQT) study, in healthy subjects

SAT101 - A randomized, double-blind study to evaluate the safety and tolerability of KB174, a novel synthetic glycan, in patients with well-compensated cirrhosis

A randomized, double-blind study to evaluate the safety and tolerability of KB174, a novel synthetic glycan, in patients with well-compensated cirrhosis

SAT143 - Microbiome metabolic therapies reduce microbiota-associated ammonia in ex vivo fecal samples from healthy subjects and patients with minimal hepatic encephalopathy and demonstrate improved tolerability over lactulose in a clinical study

Microbiome metabolic therapies reduce microbiota-associated ammonia in ex vivo fecal samples from healthy subjects and patients with minimal hepatic encephalopathy and demonstrate improved tolerability over lactulose in a clinical study

Tu1711 A RANDOMIZED, DOUBLE-BLIND STUDY TO EVALUATE THE SAFETY AND TOLERABILITY OF KB174, A NOVEL SYNTHETIC GLYCAN, IN PATIENTS WITH WELL-COMPENSATED CIRRHOSIS

Long-Term Safety and Efficacy of Mipomersen in Patients with Familial Hypercholesterolemia Uncontrolled by Maximally Tolerated Lipid Lowering Therapy

Migration and Right Atrial Perforation of an Accufix Atrial Lead Retention Wire Following Partial Lead Removal During Myomectomy

12 – Impact of Iw-3718, a Novel Gastric-Retentive Bile Acid Sequestrant, on a Spectrum of Gerd Symptoms in Patients with Persistent Gerd Receiving Ppis – Results from a Double-Blind, Placebo-Controlled Study

Multiple-Ascending-Dose Study of the Soluble Guanylate Cyclase Stimulator, IW-1701, in Healthy Subjects

Safety and Efficacy of the Soluble Guanylate Cyclase Stimulator Praliciguat in Patients with Heart Failure with Preserved Ejection Fraction (Capacity HFpEF): A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial

Effectiveness of bi-atrial pacing for reducing atrial fibrillation after coronary artery bypass graft surgery

Use of the Saline Infusion Electrode Catheter for Improved Energy Delivery and Increased Lesion Size in Radiofrequency Catheter Ablation

Case report: anterograde 2:1 and retrograde 3:2 Wenckebach block during atrioventricular nodal tachycardia: controversies of the upper and lower common pathways

Cardiovascular complications after radiofrequency catheter ablation of supraventricular tachyarrhythmias

Concomitant Reentrant Tachycardias from Concealed Accessory Atrioventricular Bypass Tract and Atrioventricular Nodal Reentry in a Patient with Williams Syndrome

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