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AMP activated protein kinase: a next generation target for total metabolic control

Expert opinion on therapeutic targets, 2008-01, Vol.12 (1), p.91-100

Misra, Parimal

2008

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Simvastatin may induce insulin resistance through a novel fatty acid mediated cholesterol independent mechanism

Scientific reports, 2015-09, Vol.5 (1), p.13823-13823, Article 13823

2015

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PIMT Controls Insulin Synthesis and Secretion through PDX1

International journal of molecular sciences, 2023-04, Vol.24 (9), p.8084

2023

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PIMT regulates hepatic gluconeogenesis in mice

iScience, 2023-03, Vol.26 (3), p.106120-106120, Article 106120

2023

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Cu-mediated N-arylation of 1,2,3-triazin-4-ones: Synthesis of fused triazinone derivatives as potential inhibitors of chorismate mutase

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (2), p.1146-1150

2012

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The Med1 Subunit of the Mediator Complex Induces Liver Cell Proliferation and Is Phosphorylated by AMP Kinase

The Journal of biological chemistry, 2013-09, Vol.288 (39), p.27898-27911

2013

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Defects of the Heart, Eye, and Megakaryocytes in Peroxisome Proliferator Activator Receptor-binding Protein (PBP) Null Embryos Implicate GATA Family of Transcription Factors

The Journal of biological chemistry, 2002-02, Vol.277 (5), p.3585-3592

2002

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Peroxisome proliferator-activated receptor-α activation and excess energy burning in hepatocarcinogenesis

Biochimie, 2014-03, Vol.98, p.63-74

2014

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ERK2-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP at Ser298 augments hepatic gluconeogenesis

PloS one, 2013, Vol.8 (12), p.e83787

2013

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PIMT/TGS1: An evolving metabolic molecular switch with conserved methyl transferase activity

Drug discovery today, 2022-08, Vol.27 (8), p.2386-2393

2022

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The role of AMP kinase in diabetes

Indian journal of medical research (New Delhi, India : 1994), 2007-03, Vol.125 (3), p.389

2007

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An inexpensive, metal-free and one-pot approach towards N-sulfonyl amidines: Identification of a chorismate mutase inhibitor with activities against S. aureus

Journal of molecular structure, 2024-09, Vol.1312, p.138531, Article 138531

2024

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Conformationally restricted 3,4-diarylfuranones (2,3a,4,5-tetrahydronaphthofuranones) as selective cyclooxygenase-2 inhibitors

Bioorganic & medicinal chemistry letters, 2003-05, Vol.13 (10), p.1639-1643

2003

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TGS1/PIMT regulates pro-inflammatory macrophage mediated paracrine insulin resistance: Crosstalk between macrophages and skeletal muscle cells

Biochimica et biophysica acta. Molecular basis of disease, 2024-01, Vol.1870 (1), p.166878-166878, Article 166878

2024

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Interaction of PIMT with Transcriptional Coactivators CBP, p300, and PBP Differential Role in Transcriptional Regulation

The Journal of biological chemistry, 2002-05, Vol.277 (22), p.20011-20019

2002

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De novo design of anti-tuberculosis agents using a structure-based deep learning method

Journal of molecular graphics & modelling, 2023-01, Vol.118, p.108361-108361, Article 108361

2023

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Pd/Cu-catalyzed access to novel 3-(benzofuran-2-ylmethyl) substituted (pyrazolo/benzo)triazinone derivatives: their in silico / in vitro evaluation as inhibitors of chorismate mutase (CM)

RSC advances, 2022-09, Vol.12 (41), p.26686-26695

2022

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TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice

Biochimica et biophysica acta. Molecular basis of disease, 2024-01, Vol.1870 (1), p.166896-166896, Article 166896

2024

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PHLPPs: Emerging players in metabolic disorders

Drug discovery today, 2022-10, Vol.27 (10), p.103317-103317, Article 103317

2022

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Novel 4-Oxothienopyrimidinyl Propanoic Acid Derivatives as AMPActivated Protein Kinase (AMPK) Activators

Letters in drug design & discovery, 2014-07, Vol.11 (6), p.778-785

2014

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Wang resin catalysed sonochemical synthesis of pyrazolo[4,3-d]pyrimidinones and 2,3-dihydroquinazolin-4(1H)-ones: Identification of chorismate mutase inhibitors having effects on Mycobacterium tuberculosis cell viability

Bioorganic chemistry, 2023-05, Vol.134, p.106452-106452, Article 106452

2023

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A microneedle transdermal patch loaded with iron() nanoparticles for non-invasive sustained delivery to combat anemia

Materials advances, 2024-04, Vol.5 (8), p.3247-3256

2024

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Statins exacerbate glucose intolerance and hyperglycemia in a high sucrose fed rodent model

Scientific reports, 2019-06, Vol.9 (1), p.8825-9, Article 8825

2019

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MicroRNA-16 modulates macrophage polarization leading to improved insulin sensitivity in myoblasts

Biochimie, 2015-12, Vol.119, p.16-26

2015

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ERK1/2 activated PHLPP1 induces skeletal muscle ER stress through the inhibition of a novel substrate AMPK

Biochimica et biophysica acta, 2018-05, Vol.1864 (5), p.1702-1716

2018

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AMP activated protein kinase: a next generation target for total metabolic control

Simvastatin may induce insulin resistance through a novel fatty acid mediated cholesterol independent mechanism

PIMT Controls Insulin Synthesis and Secretion through PDX1

PIMT regulates hepatic gluconeogenesis in mice

Cu-mediated N-arylation of 1,2,3-triazin-4-ones: Synthesis of fused triazinone derivatives as potential inhibitors of chorismate mutase

The Med1 Subunit of the Mediator Complex Induces Liver Cell Proliferation and Is Phosphorylated by AMP Kinase

Defects of the Heart, Eye, and Megakaryocytes in Peroxisome Proliferator Activator Receptor-binding Protein (PBP) Null Embryos Implicate GATA Family of Transcription Factors

Peroxisome proliferator-activated receptor-α activation and excess energy burning in hepatocarcinogenesis

ERK2-mediated phosphorylation of transcriptional coactivator binding protein PIMT/NCoA6IP at Ser298 augments hepatic gluconeogenesis

PIMT/TGS1: An evolving metabolic molecular switch with conserved methyl transferase activity

The role of AMP kinase in diabetes

An inexpensive, metal-free and one-pot approach towards N-sulfonyl amidines: Identification of a chorismate mutase inhibitor with activities against S. aureus

Conformationally restricted 3,4-diarylfuranones (2,3a,4,5-tetrahydronaphthofuranones) as selective cyclooxygenase-2 inhibitors

TGS1/PIMT regulates pro-inflammatory macrophage mediated paracrine insulin resistance: Crosstalk between macrophages and skeletal muscle cells

Interaction of PIMT with Transcriptional Coactivators CBP, p300, and PBP Differential Role in Transcriptional Regulation

De novo design of anti-tuberculosis agents using a structure-based deep learning method

Pd/Cu-catalyzed access to novel 3-(benzofuran-2-ylmethyl) substituted (pyrazolo/benzo)triazinone derivatives: their in silico / in vitro evaluation as inhibitors of chorismate mutase (CM)

TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice

PHLPPs: Emerging players in metabolic disorders

Novel 4-Oxothienopyrimidinyl Propanoic Acid Derivatives as AMPActivated Protein Kinase (AMPK) Activators

Wang resin catalysed sonochemical synthesis of pyrazolo[4,3-d]pyrimidinones and 2,3-dihydroquinazolin-4(1H)-ones: Identification of chorismate mutase inhibitors having effects on Mycobacterium tuberculosis cell viability

A microneedle transdermal patch loaded with iron() nanoparticles for non-invasive sustained delivery to combat anemia

Statins exacerbate glucose intolerance and hyperglycemia in a high sucrose fed rodent model

MicroRNA-16 modulates macrophage polarization leading to improved insulin sensitivity in myoblasts

ERK1/2 activated PHLPP1 induces skeletal muscle ER stress through the inhibition of a novel substrate AMPK

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