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Phase 1 Evaluation of Elezanumab (Anti–Repulsive Guidance Molecule A Monoclonal Antibody) in Healthy and Multiple Sclerosis Participants

Annals of neurology, 2023-02, Vol.93 (2), p.285-296

2023

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Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis

PloS one, 2011-04, Vol.6 (4), p.e18850-e18850

2011

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Immunoaffinity liquid chromatography–tandem mass spectrometry detection of nitrotyrosine in biological fluids: Development of a clinically translatable biomarker

Analytical biochemistry, 2008-09, Vol.380 (1), p.68-76

2008

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Inactivation of Catecholamines by Superoxide Gives New Insights on the Pathogenesis of Septic Shock

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (17), p.9753-9758

2000

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Protein geranylgeranylation controls collagenase expression in osteoarthritic cartilage

Osteoarthritis and cartilage, 2010-07, Vol.18 (7), p.948-955

2010

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Peroxynitrite Decomposition Catalysts: Therapeutics for Peroxynitrite-Mediated Pathology

Proceedings of the National Academy of Sciences - PNAS, 1998-03, Vol.95 (5), p.2659-2663

1998

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A Nonpeptidyl Mimic of Superoxide Dismutase with Therapeutic Activity in Rats

Science (American Association for the Advancement of Science), 1999-10, Vol.286 (5438), p.304-306

1999

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Optical tomographic imaging discriminates between disease-modifying anti-rheumatic drug (DMARD) and non-DMARD efficacy in collagen antibody-induced arthritis

Arthritis research & therapy, 2010-01, Vol.12 (3), p.R105-R105

2010

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Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation

Diabetes (New York, N.Y.), 1993-02, Vol.42 (2), p.221

1993

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Gene transfer and molecular cloning of the rat nerve growth factor receptor

Nature (London), 1987-02, Vol.325 (6105), p.593-597

1987

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Nitric Oxide Activates Cyclooxygenase Enzymes

Proceedings of the National Academy of Sciences - PNAS, 1993-08, Vol.90 (15), p.7240-7244

1993

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Characterization of the Cytoprotective Action of Peroxynitrite Decomposition Catalysts

The Journal of biological chemistry, 1998-06, Vol.273 (25), p.15646-15653

1998

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Peroxynitrite formation within the central nervous system in active multiple sclerosis

Journal of neuroimmunology, 1998-08, Vol.88 (1), p.45-56

1998

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Selective inhibition of the inducible nitric oxide synthase by aminoguanidine

European journal of pharmacology, 1993-03, Vol.233 (1), p.119-125

1993

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Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion

The FASEB journal, 2000-06, Vol.14 (9), p.1061-1072

2000

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Inhibition of Inducible Nitric Oxide Synthase Prevents Myocardial and Systemic Vascular Barrier Dysfunction During Early Cardiac Allograft Rejection

Circulation research, 1996-05, Vol.78 (5), p.769-779

1996

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Protective effects of a superoxide dismutase mimetic and peroxynitrite decomposition catalysts in endotoxin‐induced intestinal damage

British journal of pharmacology, 1999-06, Vol.127 (3), p.685-692

1999

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Biochemical, cellular, and anti-inflammatory properties of a potent, selective, orally bioavailable benzamide inhibitor of Rho kinase activity

The Journal of pharmacology and experimental therapeutics, 2010-06, Vol.333 (3), p.707

2010

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Evidence for the production of peroxynitrite in inflammatory CNS demyelination

Journal of neuroimmunology, 1997-12, Vol.80 (1), p.121-130

1997

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Experimental allergic encephalomyelitis in the rat is inhibited by aminoguanidine, an inhibitor of nitric oxide synthase

Journal of neuroimmunology, 1996-02, Vol.64 (2), p.123-133

1996

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TNF-alpha causes reversible in vivo systemic vascular barrier dysfunction via NO-dependent and -independent mechanisms

American journal of physiology. Heart and circulatory physiology, 1997-12, Vol.273 (6), p.H2565-H2574

1997

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Nitric Oxide Production in Islets from Nonobese Diabetic Mice: Aminoguanidine-Sensitive and -Resistant Stages in the Immunological Diabetic Process

Proceedings of the National Academy of Sciences - PNAS, 1993-10, Vol.90 (19), p.8992-8995

1993

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Inducible nitric oxide synthase gene expression and enzyme activity correlate with disease activity in murine experimental autoimmune encephalomyelitis

Journal of neuroimmunology, 1996-12, Vol.71 (1), p.145-153

1996

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2-Iminopiperidine and Other 2-Iminoazaheterocycles as Potent Inhibitors of Human Nitric Oxide Synthase Isoforms

Journal of medicinal chemistry, 1996-02, Vol.39 (3), p.669-672

1996

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2-Iminohomopiperidinium Salts as Selective Inhibitors of Inducible Nitric Oxide Synthase (iNOS)

Journal of medicinal chemistry, 1998-04, Vol.41 (9), p.1361-1366

1998

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Phase 1 Evaluation of Elezanumab (Anti–Repulsive Guidance Molecule A Monoclonal Antibody) in Healthy and Multiple Sclerosis Participants

Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis

Immunoaffinity liquid chromatography–tandem mass spectrometry detection of nitrotyrosine in biological fluids: Development of a clinically translatable biomarker

Inactivation of Catecholamines by Superoxide Gives New Insights on the Pathogenesis of Septic Shock

Protein geranylgeranylation controls collagenase expression in osteoarthritic cartilage

Peroxynitrite Decomposition Catalysts: Therapeutics for Peroxynitrite-Mediated Pathology

A Nonpeptidyl Mimic of Superoxide Dismutase with Therapeutic Activity in Rats

Optical tomographic imaging discriminates between disease-modifying anti-rheumatic drug (DMARD) and non-DMARD efficacy in collagen antibody-induced arthritis

Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation

Gene transfer and molecular cloning of the rat nerve growth factor receptor

Nitric Oxide Activates Cyclooxygenase Enzymes

Characterization of the Cytoprotective Action of Peroxynitrite Decomposition Catalysts

Peroxynitrite formation within the central nervous system in active multiple sclerosis

Selective inhibition of the inducible nitric oxide synthase by aminoguanidine

Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion

Inhibition of Inducible Nitric Oxide Synthase Prevents Myocardial and Systemic Vascular Barrier Dysfunction During Early Cardiac Allograft Rejection

Protective effects of a superoxide dismutase mimetic and peroxynitrite decomposition catalysts in endotoxin‐induced intestinal damage

Biochemical, cellular, and anti-inflammatory properties of a potent, selective, orally bioavailable benzamide inhibitor of Rho kinase activity

Evidence for the production of peroxynitrite in inflammatory CNS demyelination

Experimental allergic encephalomyelitis in the rat is inhibited by aminoguanidine, an inhibitor of nitric oxide synthase

TNF-alpha causes reversible in vivo systemic vascular barrier dysfunction via NO-dependent and -independent mechanisms

Nitric Oxide Production in Islets from Nonobese Diabetic Mice: Aminoguanidine-Sensitive and -Resistant Stages in the Immunological Diabetic Process

Inducible nitric oxide synthase gene expression and enzyme activity correlate with disease activity in murine experimental autoimmune encephalomyelitis

2-Iminopiperidine and Other 2-Iminoazaheterocycles as Potent Inhibitors of Human Nitric Oxide Synthase Isoforms

2-Iminohomopiperidinium Salts as Selective Inhibitors of Inducible Nitric Oxide Synthase (iNOS)

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