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Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

Oncogene, 2002-04, Vol.21 (17), p.2613-2622

2002

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Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets

PLoS pathogens, 2016-05, Vol.12 (5), p.e1005585-e1005585

2016

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Development of a Cell-Based Reporter Potency Assay for Live Virus Vaccines

Vaccines (Basel), 2024-07, Vol.12 (7), p.769

2024

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Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression

Oncogene, 2003-06, Vol.22 (23), p.3645-3654

2003

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Analyses of p53 Target Genes in the Human Genome by Bioinformatic and Microarray Approaches

The Journal of biological chemistry, 2001-11, Vol.276 (47), p.43604-43610

2001

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The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

Nature (London), 1995-05, Vol.375 (6527), p.151-155

1995

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RNA interference targeting of A1 receptor-overexpressing breast carcinoma cells leads to diminished rates of cell proliferation and induction of apoptosis

Cancer biology & therapy, 2005-12, Vol.4 (12), p.1355-1360

2005

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Transcriptional Regulation during p21/-induced Apoptosis in Human Ovarian Cancer Cells

The Journal of biological chemistry, 2002-09, Vol.277 (39), p.36329-36337

2002

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Integrative Genomics Revealed RAI3 Is a Cell Growth-promoting Gene and a Novel P53 Transcriptional Target

The Journal of biological chemistry, 2005-04, Vol.280 (13), p.12935-12943

2005

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Generation or large numbers of immature and mature dendritic cells from rat bone marrow cultures

European journal of immunology, 1998-03, Vol.28 (3), p.811-817

1998

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Sequestration from Immune CD4$^+$ T Cells of Mycobacteria Growing in Human Macrophages

Science (American Association for the Advancement of Science), 1993-05, Vol.260 (5110), p.984-986

1993

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Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration

Journal of medicinal chemistry, 2024-03, Vol.67 (5), p.3400-3418

2024

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Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates

Journal of medicinal chemistry, 2022-12, Vol.65 (24), p.16234-16251

2022

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The Farnesyl Transferase Inhibitor (FTI) SCH66336 (lonafarnib) Inhibits Rheb Farnesylation and mTOR Signaling

The Journal of biological chemistry, 2005-09, Vol.280 (35), p.31101-31108

2005

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1723. MK-3866, a metallo-β-lactamase inhibitor, is not subject to efflux in Pseudomonas aeruginosa

Open forum infectious diseases, 2022-12, Vol.9 (Supplement_2)

2022

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The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity

The Journal of biological chemistry, 2005-09, Vol.280 (35), p.31101-31108

2005

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Developmental regulation of MHC class II transport in mouse dendritic cells

Nature (London), 1997-08, Vol.388 (6644), p.787-792

1997

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Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors

ACS medicinal chemistry letters, 2016-03, Vol.7 (3), p.324-329

2016

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Abstract 2785: Discovery of a novel HDM2 inhibitor with potent in vivo anti-tumor activity

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.2785-2785

2012

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Abstract 3197: Differential senescent and apoptotic responses to HDM2 antagonism in p53 wild-type human solid cancer cells

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.3197-3197

2010

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Generation of p53 target database via integration of microarray and global p53 DNA-binding site analysis

Methods in molecular biology (Clifton, N.J.), 2004, Vol.281, p.33

2004

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Transforming Growth Factor-β2 Is a Transcriptional Target for Akt/Protein Kinase B via Forkhead Transcription Factor

The Journal of biological chemistry, 2002-08, Vol.277 (31), p.28118-28126

2002

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Abstract 4533: In vivo activation of the p53 pathway leading to tumor regression by a novel and potent HDM2 antagonist SCH 1450206

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.4533-4533

2010

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Abstract 4534: A novel and potent small molecule antagonist of HDM2, SCH 1450206, activates the p53 pathway with mechanism-based activity

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.4534-4534

2010

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Transforming growth factor-beta 2 is a transcriptional target for Akt/protein kinase B via forkhead transcription factor

The Journal of biological chemistry, 2002-08, Vol.277 (31), p.28118-28126

2002

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Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets

Development of a Cell-Based Reporter Potency Assay for Live Virus Vaccines

Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression

Analyses of p53 Target Genes in the Human Genome by Bioinformatic and Microarray Approaches

The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

RNA interference targeting of A1 receptor-overexpressing breast carcinoma cells leads to diminished rates of cell proliferation and induction of apoptosis

Transcriptional Regulation during p21/-induced Apoptosis in Human Ovarian Cancer Cells

Integrative Genomics Revealed RAI3 Is a Cell Growth-promoting Gene and a Novel P53 Transcriptional Target

Generation or large numbers of immature and mature dendritic cells from rat bone marrow cultures

Sequestration from Immune CD4$^+$ T Cells of Mycobacteria Growing in Human Macrophages

Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration

Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates

The Farnesyl Transferase Inhibitor (FTI) SCH66336 (lonafarnib) Inhibits Rheb Farnesylation and mTOR Signaling

1723. MK-3866, a metallo-β-lactamase inhibitor, is not subject to efflux in Pseudomonas aeruginosa

The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity

Developmental regulation of MHC class II transport in mouse dendritic cells

Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors

Abstract 2785: Discovery of a novel HDM2 inhibitor with potent in vivo anti-tumor activity

Abstract 3197: Differential senescent and apoptotic responses to HDM2 antagonism in p53 wild-type human solid cancer cells

Generation of p53 target database via integration of microarray and global p53 DNA-binding site analysis

Transforming Growth Factor-β2 Is a Transcriptional Target for Akt/Protein Kinase B via Forkhead Transcription Factor

Abstract 4533: In vivo activation of the p53 pathway leading to tumor regression by a novel and potent HDM2 antagonist SCH 1450206

Abstract 4534: A novel and potent small molecule antagonist of HDM2, SCH 1450206, activates the p53 pathway with mechanism-based activity

Transforming growth factor-beta 2 is a transcriptional target for Akt/protein kinase B via forkhead transcription factor

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