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Role of the 12-lipoxygenase pathway in diabetes pathogenesis and complications

Pharmacology & therapeutics (Oxford), 2019-03, Vol.195, p.100-110

2019

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Lost in translation: endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus

Diabetes, obesity & metabolism, 2013-09, Vol.15 (s3), p.159-169

2013

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Targeting regulatory T cells in the treatment of type 1 diabetes mellitus

Current molecular medicine, 2012-12, Vol.12 (10), p.1261

2012

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A system for detecting high impact-low frequency mutations in primary tumors and metastases

Oncogene, 2018-01, Vol.37 (2), p.185-196

2018

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Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding

The Journal of biological chemistry, 2002-04, Vol.277 (15), p.13286-13293

2002

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Effects of combination therapy with dipeptidyl peptidase‐IV and histone deacetylase inhibitors in the non‐obese diabetic mouse model of type 1 diabetes

Clinical and experimental immunology, 2013-06, Vol.172 (3), p.375-382

2013

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P1405: ARGININE‐DEPENDENT REGULATION OF THE EUKARYOTIC TRANSLATION INITIATION FACTOR (EIF)5A CONTROLS HUMAN HEMATOPOIETIC PROGENITOR FATE TO THE ERYTHROID LINEAGE

HemaSphere, 2022-06, Vol.6 (Suppl), p.1289-1290

2022

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Regulation of the Pancreatic Pro-Endocrine Gene Neurogenin3

Diabetes (New York, N.Y.), 2001-05, Vol.50 (5), p.928-936

2001

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Covalent histone modifications underlie the developmental regulation of insulin gene transcription in pancreatic beta cells

The Journal of biological chemistry, 2003-06, Vol.278 (26), p.23617-23623

2003

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The Homeodomain of PDX-1 Mediates Multiple Protein-Protein Interactions in the Formation of a Transcriptional Activation Complex on the Insulin Promoter

Molecular and Cellular Biology, 2000-02, Vol.20 (3), p.900-911

2000

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Role of the phenylalanine B24 side chain in directing insulin interaction with its receptor. Importance of main chain conformation

The Journal of biological chemistry, 1989-04, Vol.264 (11), p.6349-6354

1989

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Importance of the character and configuration of residues B24, B25, and B26 in insulin-receptor interactions

The Journal of biological chemistry, 1991-01, Vol.266 (3), p.1428-1436

1991

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Differential expression of cell cycle proteins during ageing of pancreatic islet cells

Diabetes, obesity & metabolism, 2008-11, Vol.10 (s4), p.136-146

2008

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Intramolecular Control of Transcriptional Activity by the NK2-Specific Domain in NK-2 Homeodomain Proteins

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (17), p.9443-9448

2000

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The Transcriptional Repressor Nkx6.1 Also Functions as a Deoxyribonucleic Acid Context-Dependent Transcriptional Activator during Pancreatic β-Cell Differentiation: Evidence for Feedback Activation of the nkx6.1 Gene by Nkx6.1

Molecular endocrinology (Baltimore, Md.), 2004-06, Vol.18 (6), p.1363-1375

2004

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Transcriptional and Translational Regulation of β-Cell Differentiation Factor Nkx6.1

The Journal of biological chemistry, 2000-11, Vol.275 (44), p.34224-34230

2000

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The C-Terminal Domain of the β Cell Homeodomain Factor Nkx6.1 Enhances Sequence-Selective DNA Binding at the insulin Promoter

Biochemistry (Easton), 2005-08, Vol.44 (33), p.11269-11278

2005

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β-Cell Differentiation Factor Nkx6.1 Contains Distinct DNA Binding Interference and Transcriptional Repression Domains

The Journal of biological chemistry, 2000-05, Vol.275 (19), p.14743-14751

2000

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An insulin-like growth factor I/insulin hybrid exhibiting high potency for interaction with the type I insulin-like growth factor and insulin receptors of placental plasma membranes

The Journal of biological chemistry, 1990-10, Vol.265 (29), p.17820-17825

1990

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Disposition of the phenylalanine B25 side chain during insulin-receptor and insulin-insulin interactions

Biochemistry (Easton), 1991-08, Vol.30 (33), p.8222-8229

1991

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Lost in translation: endoplasmic reticulum stress and the decline of [beta]-cell health in diabetes mellitus

Diabetes, obesity & metabolism, 2013-09, Vol.15 (s3), p.159

2013

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Interactions of a hybrid insulin/insulin-like growth factor-I analog with chimeric insulin/type I insulin-like growth factor receptors

The Journal of biological chemistry, 1993-02, Vol.268 (5), p.3044-3047

1993

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The Nkx6.1 Homeodomain Transcription Factor Suppresses Glucagon Expression and Regulates Glucose-Stimulated Insulin Secretion in Islet Beta Cells

Proceedings of the National Academy of Sciences - PNAS, 2005-05, Vol.102 (20), p.7297-7302

2005

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Transcription factors direct the development and function of pancreatic β cells

Trends in endocrinology and metabolism, 2003-03, Vol.14 (2), p.78-84

2003

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Pdx-1 Links Histone H3-Lys-4 Methylation to RNA Polymerase II Elongation during Activation of Insulin Transcription

The Journal of biological chemistry, 2005-10, Vol.280 (43), p.36244-36253

2005

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Role of the 12-lipoxygenase pathway in diabetes pathogenesis and complications

Lost in translation: endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus

Targeting regulatory T cells in the treatment of type 1 diabetes mellitus

A system for detecting high impact-low frequency mutations in primary tumors and metastases

Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding

Effects of combination therapy with dipeptidyl peptidase‐IV and histone deacetylase inhibitors in the non‐obese diabetic mouse model of type 1 diabetes

P1405: ARGININE‐DEPENDENT REGULATION OF THE EUKARYOTIC TRANSLATION INITIATION FACTOR (EIF)5A CONTROLS HUMAN HEMATOPOIETIC PROGENITOR FATE TO THE ERYTHROID LINEAGE

Regulation of the Pancreatic Pro-Endocrine Gene Neurogenin3

Covalent histone modifications underlie the developmental regulation of insulin gene transcription in pancreatic beta cells

The Homeodomain of PDX-1 Mediates Multiple Protein-Protein Interactions in the Formation of a Transcriptional Activation Complex on the Insulin Promoter

Role of the phenylalanine B24 side chain in directing insulin interaction with its receptor. Importance of main chain conformation

Importance of the character and configuration of residues B24, B25, and B26 in insulin-receptor interactions

Differential expression of cell cycle proteins during ageing of pancreatic islet cells

Intramolecular Control of Transcriptional Activity by the NK2-Specific Domain in NK-2 Homeodomain Proteins

The Transcriptional Repressor Nkx6.1 Also Functions as a Deoxyribonucleic Acid Context-Dependent Transcriptional Activator during Pancreatic β-Cell Differentiation: Evidence for Feedback Activation of the nkx6.1 Gene by Nkx6.1

Transcriptional and Translational Regulation of β-Cell Differentiation Factor Nkx6.1

The C-Terminal Domain of the β Cell Homeodomain Factor Nkx6.1 Enhances Sequence-Selective DNA Binding at the insulin Promoter

β-Cell Differentiation Factor Nkx6.1 Contains Distinct DNA Binding Interference and Transcriptional Repression Domains

An insulin-like growth factor I/insulin hybrid exhibiting high potency for interaction with the type I insulin-like growth factor and insulin receptors of placental plasma membranes

Disposition of the phenylalanine B25 side chain during insulin-receptor and insulin-insulin interactions

Lost in translation: endoplasmic reticulum stress and the decline of [beta]-cell health in diabetes mellitus

Interactions of a hybrid insulin/insulin-like growth factor-I analog with chimeric insulin/type I insulin-like growth factor receptors

The Nkx6.1 Homeodomain Transcription Factor Suppresses Glucagon Expression and Regulates Glucose-Stimulated Insulin Secretion in Islet Beta Cells

Transcription factors direct the development and function of pancreatic β cells

Pdx-1 Links Histone H3-Lys-4 Methylation to RNA Polymerase II Elongation during Activation of Insulin Transcription

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