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Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V

PloS one, 2018-05, Vol.13 (5), p.e0196791-e0196791

2018

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Molecular Mechanism of Hepcidin-Mediated Ferroportin Internalization Requires Ferroportin Lysines, Not Tyrosines or JAK-STAT

Cell metabolism, 2012-06, Vol.15 (6), p.905-917

2012

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Hepcidin Revisited, Disulfide Connectivity, Dynamics, and Structure

The Journal of biological chemistry, 2009-09, Vol.284 (36), p.24155-24167

2009

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A Potent d‑Protein Antagonist of VEGF‑A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo

ACS chemical biology, 2016-04, Vol.11 (4), p.1058-1065

2016

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Epitope Discovery for a Synthetic Polymer Nanoparticle: A New Strategy for Developing a Peptide Tag

Journal of the American Chemical Society, 2014-01, Vol.136 (4), p.1194-1197

2014

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Development of human-machine language interfaces for the visual analysis of complex biologics and RNA modalities and associated experimental data

AAPS open, 2023-03, Vol.9 (1), p.5-11, Article 5

2023

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Utilization of tyrosine- and histidine-containing dipeptides to enhance productivity and culture viability

Biotechnology and bioengineering, 2012-09, Vol.109 (9), p.2286-2294

2012

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Identification of Antibody and Small Molecule Antagonists of Ferroportin-Hepcidin Interaction

Frontiers in pharmacology, 2017-11, Vol.8, p.838-838

2017

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Structure-guided Discovery of Dual-recognition Chemibodies

Scientific reports, 2018-05, Vol.8 (1), p.7570-9, Article 7570

2018

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Progress and challenges in the optimization of toxin peptides for development as pain therapeutics

Current opinion in chemical biology, 2017-06, Vol.38, p.70-79

2017

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Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LC-MS/MS

Journal of pharmacological and toxicological methods, 2009-05, Vol.59 (3), p.171-180

2009

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Design and Chemical Synthesis of a Homogeneous Polymer-Modified Erythropoiesis Protein

Science (American Association for the Advancement of Science), 2003-02, Vol.299 (5608), p.884-887

2003

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Probing the S100 protein family through genomic and functional analysis

Genomics (San Diego, Calif.), 2004-07, Vol.84 (1), p.10-22

2004

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Engineering Potent and Selective Analogues of GpTx-1, a Tarantula Venom Peptide Antagonist of the NaV1.7 Sodium Channel

Journal of medicinal chemistry, 2015-03, Vol.58 (5), p.2299-2314

2015

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Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel

Journal of medicinal chemistry, 2015-03, Vol.58 (5), p.2299-2314

2015

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Single Residue Substitutions That Confer Voltage-Gated Sodium Ion Channel Subtype Selectivity in the NaV1.7 Inhibitory Peptide GpTx‑1

Journal of medicinal chemistry, 2016-03, Vol.59 (6), p.2704-2717

2016

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Accelerating attribute‐focused process and product development through the development and deployment of autonomous process analytical technology platform system

Biotechnology and bioengineering, 2024-04, Vol.121 (4), p.1257-1270

2024

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Process development of a SARS-CoV-2 nanoparticle vaccine

Process biochemistry (1991), 2023-06, Vol.129, p.241-256

2023

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Metal-Free Polymer-Based Affinity Medium for Selective Purification of His6-Tagged Proteins

Biomacromolecules, 2021-04, Vol.22 (4), p.1695-1705

2021

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Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring

Biotechnology and bioengineering, 2019-09, Vol.116 (9), p.2393-2411

2019

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Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx‑V Peptide 5‑Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis

Journal of medicinal chemistry, 2018-11, Vol.61 (21), p.9500-9512

2018

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Discovery of Selective Pituitary Adenylate Cyclase 1 Receptor (PAC1R) Antagonist Peptides Potent in a Maxadilan/PACAP38-Induced Increase in Blood Flow Pharmacodynamic Model

Journal of medicinal chemistry, 2021-03, Vol.64 (6), p.3427-3438

2021

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Half-life extension of peptidic APJ agonists by N-terminal lipid conjugation

Bioorganic & medicinal chemistry letters, 2020-11, Vol.30 (21), p.127499-127499, Article 127499

2020

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Accelerated Chemical Synthesis of Peptides and Small Proteins

Proceedings of the National Academy of Sciences - PNAS, 1999-02, Vol.96 (4), p.1181-1186

1999

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Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3

Journal of medicinal chemistry, 2015-09, Vol.58 (17), p.6784-6802

2015

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Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V

Molecular Mechanism of Hepcidin-Mediated Ferroportin Internalization Requires Ferroportin Lysines, Not Tyrosines or JAK-STAT

Hepcidin Revisited, Disulfide Connectivity, Dynamics, and Structure

A Potent d‑Protein Antagonist of VEGF‑A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo

Epitope Discovery for a Synthetic Polymer Nanoparticle: A New Strategy for Developing a Peptide Tag

Development of human-machine language interfaces for the visual analysis of complex biologics and RNA modalities and associated experimental data

Utilization of tyrosine- and histidine-containing dipeptides to enhance productivity and culture viability

Identification of Antibody and Small Molecule Antagonists of Ferroportin-Hepcidin Interaction

Structure-guided Discovery of Dual-recognition Chemibodies

Progress and challenges in the optimization of toxin peptides for development as pain therapeutics

Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LC-MS/MS

Design and Chemical Synthesis of a Homogeneous Polymer-Modified Erythropoiesis Protein

Probing the S100 protein family through genomic and functional analysis

Engineering Potent and Selective Analogues of GpTx-1, a Tarantula Venom Peptide Antagonist of the NaV1.7 Sodium Channel

Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel

Single Residue Substitutions That Confer Voltage-Gated Sodium Ion Channel Subtype Selectivity in the NaV1.7 Inhibitory Peptide GpTx‑1

Accelerating attribute‐focused process and product development through the development and deployment of autonomous process analytical technology platform system

Process development of a SARS-CoV-2 nanoparticle vaccine

Metal-Free Polymer-Based Affinity Medium for Selective Purification of His6-Tagged Proteins

Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring

Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx‑V Peptide 5‑Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis

Discovery of Selective Pituitary Adenylate Cyclase 1 Receptor (PAC1R) Antagonist Peptides Potent in a Maxadilan/PACAP38-Induced Increase in Blood Flow Pharmacodynamic Model

Half-life extension of peptidic APJ agonists by N-terminal lipid conjugation

Accelerated Chemical Synthesis of Peptides and Small Proteins

Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3

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