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ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157

Neuroscience letters, 2017-11, Vol.660, p.109-114

2017

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The selective anti-IL17A monoclonal antibody secukinumab (AIN457) attenuates IL17A-induced levels of IL6 in human astrocytes

Glia, 2014-05, Vol.62 (5), p.725-735

2014

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Fractalkine shedding is mediated by p38 and the ADAM10 protease under pro-inflammatory conditions in human astrocytes

Journal of neuroinflammation, 2016-08, Vol.13 (1), p.189-189, Article 189

2016

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Fingolimod attenuates splenocyte-induced demyelination in cerebellar slice cultures

PloS one, 2014-06, Vol.9 (6), p.e99444-e99444

2014

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Monocyte Chemoattractant Protein-1 Deficiency Is Protective in a Murine Stroke Model

Journal of cerebral blood flow and metabolism, 2002-03, Vol.22 (3), p.308-317

2002

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The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice cultures

Journal of neuroinflammation, 2016-02, Vol.13 (32), p.31-31, Article 31

2016

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Recovery and brain reorganization after stroke in adult and aged rats

Annals of neurology, 2005-12, Vol.58 (6), p.950-953

2005

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Neutralization of interleukin-1β reduces cerebral edema and tissue loss and improves late cognitive outcome following traumatic brain injury in mice

The European journal of neuroscience, 2011-07, Vol.34 (1), p.110-123

2011

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Neutralization of interleukin-1β modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice

The European journal of neuroscience, 2009-08, Vol.30 (3), p.385-396

2009

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Delayed anti-nogo-a antibody application after spinal cord injury shows progressive loss of responsiveness

Journal of neurotrauma, 2012-02, Vol.29 (3), p.567-578

2012

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Diffuse traumatic axonal injury in mice induces complex behavioural alterations that are normalized by neutralization of interleukin-1β

The European journal of neuroscience, 2016-04, Vol.43 (8), p.1016-1033

2016

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Anti-Nogo-A Antibody Infusion 24 Hours After Experimental Stroke Improved Behavioral Outcome and Corticospinal Plasticity in Normotensive and Spontaneously Hypertensive Rats

Journal of cerebral blood flow and metabolism, 2003-02, Vol.23 (2), p.154-165

2003

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Intrathecal treatment with anti-Nogo-A antibody improves functional recovery in adult rats after stroke

Experimental brain research, 2007-09, Vol.182 (2), p.261-266

2007

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Targeting monocyte chemoattractant protein-1 signalling in disease

Expert opinion on therapeutic targets, 2003-02, Vol.7 (1), p.35-48

2003

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Cognitive outcome following brain injury and treatment with an inhibitor of Nogo-A in association with an attenuated downregulation of hippocampal growth-associated protein-43 expression

Journal of neurosurgery, 2007-10, Vol.107 (4), p.844-853

2007

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Nogo-A inhibition induces recovery from neglect in rats

Behavioural brain research, 2008-03, Vol.187 (2), p.262-272

2008

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Anti-Nogo-A antibody infusion 24 hours after experimental stroke improved behavioral outcome and corticospinal plasticity in normotensive and spontaneously hypertensive rats

Journal of cerebral blood flow and metabolism, 2003-02, Vol.23 (2), p.154-165

2003

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Zinc metalloproteinase-mediated cleavage of the human Nogo-66 receptor

Journal of cell science, 2004-09, Vol.117 (Pt 19), p.4591-4602

2004

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Ectodomain shedding of human Nogo-66 receptor homologue-1 by zinc metalloproteinases

Biochemical and biophysical research communications, 2005-02, Vol.327 (1), p.112-116

2005

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The selective anti-IL17A monoclonal antibody secukinumab (AIN457) attenuates IL17A-induced levels of IL6 in human astrocytes: IL17 Regulates IL16 Levels in Astrocytes

Glia, 2014-05, Vol.62 (5), p.725-735

2014

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Similar time-course of interleukin-1 beta production and extracellular-signal-regulated kinase (ERK) activation in permanent focal brain ischemic injury

Metabolic brain disease, 2002-09, Vol.17 (3), p.131-138

2002

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Graphics computer-aided receptor mapping as a predictive tool for drug design: development of potent, selective, and stereospecific ligands for the 5-HT1A receptor

Journal of medicinal chemistry, 1988-06, Vol.31 (6), p.1087-1093

1988

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Cardiovascular response to 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) in the rat: site of action and pharmacological analysis

Journal of cardiovascular pharmacology, 1987-03, Vol.9 (3), p.328-347

1987

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Neutralization of interleukin-1β reduces cerebral edema and tissue loss and improves late cognitive outcome following traumatic brain injury in mice: IL-1β inhibition improves outcome after TBI

The European journal of neuroscience, 2011-07, Vol.34 (1), p.110-123

2011

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Role of the adrenal medulla in the metabolic and pressor actions of 8‐OH‐DPAT

British journal of pharmacology, 1992-01, Vol.105 (1), p.159-163

1992

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ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157

The selective anti-IL17A monoclonal antibody secukinumab (AIN457) attenuates IL17A-induced levels of IL6 in human astrocytes

Fractalkine shedding is mediated by p38 and the ADAM10 protease under pro-inflammatory conditions in human astrocytes

Fingolimod attenuates splenocyte-induced demyelination in cerebellar slice cultures

Monocyte Chemoattractant Protein-1 Deficiency Is Protective in a Murine Stroke Model

The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice cultures

Recovery and brain reorganization after stroke in adult and aged rats

Neutralization of interleukin-1β reduces cerebral edema and tissue loss and improves late cognitive outcome following traumatic brain injury in mice

Neutralization of interleukin-1β modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice

Delayed anti-nogo-a antibody application after spinal cord injury shows progressive loss of responsiveness

Diffuse traumatic axonal injury in mice induces complex behavioural alterations that are normalized by neutralization of interleukin-1β

Anti-Nogo-A Antibody Infusion 24 Hours After Experimental Stroke Improved Behavioral Outcome and Corticospinal Plasticity in Normotensive and Spontaneously Hypertensive Rats

Intrathecal treatment with anti-Nogo-A antibody improves functional recovery in adult rats after stroke

Targeting monocyte chemoattractant protein-1 signalling in disease

Cognitive outcome following brain injury and treatment with an inhibitor of Nogo-A in association with an attenuated downregulation of hippocampal growth-associated protein-43 expression

Nogo-A inhibition induces recovery from neglect in rats

Anti-Nogo-A antibody infusion 24 hours after experimental stroke improved behavioral outcome and corticospinal plasticity in normotensive and spontaneously hypertensive rats

Zinc metalloproteinase-mediated cleavage of the human Nogo-66 receptor

Ectodomain shedding of human Nogo-66 receptor homologue-1 by zinc metalloproteinases

The selective anti-IL17A monoclonal antibody secukinumab (AIN457) attenuates IL17A-induced levels of IL6 in human astrocytes: IL17 Regulates IL16 Levels in Astrocytes

Similar time-course of interleukin-1 beta production and extracellular-signal-regulated kinase (ERK) activation in permanent focal brain ischemic injury

Graphics computer-aided receptor mapping as a predictive tool for drug design: development of potent, selective, and stereospecific ligands for the 5-HT1A receptor

Cardiovascular response to 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) in the rat: site of action and pharmacological analysis

Neutralization of interleukin-1β reduces cerebral edema and tissue loss and improves late cognitive outcome following traumatic brain injury in mice: IL-1β inhibition improves outcome after TBI

Role of the adrenal medulla in the metabolic and pressor actions of 8‐OH‐DPAT

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