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Catching the next wave of recombinant RyR2 cryo-EM structures. Commentary on “Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations”

Cell calcium (Edinburgh), 2022-07, Vol.105, p.102614-102614, Article 102614

2022

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Copper Binding to the N‑Terminally Acetylated, Naturally Occurring Form of Alpha-Synuclein Induces Local Helical Folding

Journal of the American Chemical Society, 2015-05, Vol.137 (20), p.6444-6447

2015

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Phthalocyanines as Molecular Scaffolds to Block Disease-Associated Protein Aggregation

Accounts of chemical research, 2016-05, Vol.49 (5), p.801-808

2016

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Mitochondrial Calcium Overload Plays a Causal Role in Oxidative Stress in the Failing Heart

Biomolecules (Basel, Switzerland), 2023-09, Vol.13 (9), p.1409

2023

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Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment

Science advances, 2022-07, Vol.8 (29), p.eabo1272-eabo1272

2022

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Site-Specific Copper-Catalyzed Oxidation of α‑Synuclein: Tightening the Link between Metal Binding and Protein Oxidative Damage in Parkinson’s Disease

Inorganic chemistry, 2014-05, Vol.53 (9), p.4350-4358

2014

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Aroylhydrazones constitute a promising class of ‘metal-protein attenuating compounds’ for the treatment of Alzheimer’s disease: a proof-of-concept based on the study of the interactions between zinc(II) and pyridine-2-carboxaldehyde isonicotinoyl hydrazone

Journal of biological inorganic chemistry, 2018-12, Vol.23 (8), p.1227-1241

2018

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Bioinorganic chemistry of synucleinopathies: Deciphering the binding features of Met motifs and His-50 in AS–Cu(I) interactions

Journal of inorganic biochemistry, 2014-12, Vol.141, p.208-211

2014

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Copper Coordination Features of Human Islet Amyloid Polypeptide: The Type 2 Diabetes Peptide

Inorganic chemistry, 2016-10, Vol.55 (20), p.10727-10740

2016

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Spectroscopic and Theoretical Study of Cu(I) Binding to His111 in the Human Prion Protein Fragment 106-115

Inorganic chemistry, 2016-03, Vol.55 (6), p.2909-2922

2016

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Bioinorganic Chemistry of Parkinson’s Disease: Affinity and Structural Features of Cu(I) Binding to the Full-Length β‑Synuclein Protein

Inorganic chemistry, 2017-09, Vol.56 (17), p.10387-10395

2017

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Characterization of N-terminal RYR2 variants outside CPVT1 hotspot regions using patient iPSCs reveal pathogenesis and therapeutic potential

Stem cell reports, 2022-09, Vol.17 (9), p.2023-2036

2022

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Comparison of imaging-based and pathological dimensions in pancreatic neuroendocrine tumors

World journal of gastroenterology : WJG, 2017-05, Vol.23 (17), p.3092-3098

2017

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Spectroscopic and Theoretical Study of CuI Binding to His111 in the Human Prion Protein Fragment 106–115

Inorganic chemistry, 2016-03, Vol.55 (6), p.2909-2922

2016

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Whole-genome landscape of pancreatic neuroendocrine tumours

Nature (London), 2017-03, Vol.543 (7643), p.65-71

2017

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Role of neuronal ryanodine receptor type 2 in cardiogenic dementia

Biophysical journal, 2023-02, Vol.122 (3), p.238a-238a

2023

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Endoscopic ultrasound-guided fine-needle aspiration for the diagnosis and grading of pancreatic neuroendocrine tumors: a retrospective analysis of 110 cases

Endoscopy, 2020-11, Vol.52 (11), p.988

2020

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PO-705-07 A NOVEL RYR2 CHANNEL STABILIZER EFFECTIVELY RESCUES CALCIUM HANDLING KINETICS ASSOCIATED WITH CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA IN PATIENT-SPECIFIC INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES

Heart rhythm, 2022-05, Vol.19 (5), p.S456-S456

2022

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Patterns of Recurrence after Resection for Pancreatic Neuroendocrine Tumors: Who, When, and Where?

Neuroendocrinology, 2019-04, Vol.108 (3), p.161-171

2019

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Is there a role for near-infrared technology in laparoscopic resection of pancreatic neuroendocrine tumors? Results of the COLPAN “colour-and-resect the pancreas” study

Surgical endoscopy, 2017-11, Vol.31 (11), p.4478-4484

2017

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Patterns of Recurrence after Resection for Pancreatic Neuroendocrine Tumors: Who, When, and How?

Journal of the American College of Surgeons, 2018-10, Vol.227 (4), p.e38-e38

2018

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Lymph Node Dissection for Small Pancreatic Neuroendocrine Tumors Does Not Impact Survival

Journal of the American College of Surgeons, 2018-10, Vol.227 (4), p.S242-S243

2018

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Spectroscopic and Theoretical Study of Cu I Binding to His111 in the Human Prion Protein Fragment 106–115

Inorganic chemistry, 2016-03, Vol.55 (6), p.2909-2922

2016

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Catching the next wave of recombinant RyR2 cryo-EM structures. Commentary on “Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations”

Copper Binding to the N‑Terminally Acetylated, Naturally Occurring Form of Alpha-Synuclein Induces Local Helical Folding

Phthalocyanines as Molecular Scaffolds to Block Disease-Associated Protein Aggregation

Mitochondrial Calcium Overload Plays a Causal Role in Oxidative Stress in the Failing Heart

Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment

Site-Specific Copper-Catalyzed Oxidation of α‑Synuclein: Tightening the Link between Metal Binding and Protein Oxidative Damage in Parkinson’s Disease

Aroylhydrazones constitute a promising class of ‘metal-protein attenuating compounds’ for the treatment of Alzheimer’s disease: a proof-of-concept based on the study of the interactions between zinc(II) and pyridine-2-carboxaldehyde isonicotinoyl hydrazone

Bioinorganic chemistry of synucleinopathies: Deciphering the binding features of Met motifs and His-50 in AS–Cu(I) interactions

Copper Coordination Features of Human Islet Amyloid Polypeptide: The Type 2 Diabetes Peptide

Spectroscopic and Theoretical Study of Cu(I) Binding to His111 in the Human Prion Protein Fragment 106-115

Bioinorganic Chemistry of Parkinson’s Disease: Affinity and Structural Features of Cu(I) Binding to the Full-Length β‑Synuclein Protein

A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson's disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies

Characterization of N-terminal RYR2 variants outside CPVT1 hotspot regions using patient iPSCs reveal pathogenesis and therapeutic potential

Comparison of imaging-based and pathological dimensions in pancreatic neuroendocrine tumors

Spectroscopic and Theoretical Study of CuI Binding to His111 in the Human Prion Protein Fragment 106–115

Whole-genome landscape of pancreatic neuroendocrine tumours

Role of neuronal ryanodine receptor type 2 in cardiogenic dementia

Endoscopic ultrasound-guided fine-needle aspiration for the diagnosis and grading of pancreatic neuroendocrine tumors: a retrospective analysis of 110 cases

The Evolution of Surgical Strategies for Pancreatic Neuroendocrine Tumors (Pan-NENs): Time-trend and Outcome Analysis From 587 Consecutive Resections at a High-volume Institution

PO-705-07 A NOVEL RYR2 CHANNEL STABILIZER EFFECTIVELY RESCUES CALCIUM HANDLING KINETICS ASSOCIATED WITH CATECHOLAMINERGIC POLYMORPHIC VENTRICULAR TACHYCARDIA IN PATIENT-SPECIFIC INDUCED PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES

Patterns of Recurrence after Resection for Pancreatic Neuroendocrine Tumors: Who, When, and Where?

Is there a role for near-infrared technology in laparoscopic resection of pancreatic neuroendocrine tumors? Results of the COLPAN “colour-and-resect the pancreas” study

Patterns of Recurrence after Resection for Pancreatic Neuroendocrine Tumors: Who, When, and How?

Lymph Node Dissection for Small Pancreatic Neuroendocrine Tumors Does Not Impact Survival

Spectroscopic and Theoretical Study of Cu I Binding to His111 in the Human Prion Protein Fragment 106–115

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