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Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures

Nature communications, 2021-05, Vol.12 (1), p.2507-2507, Article 2507

2021

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SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia

Leukemia, 2021-02, Vol.35 (2), p.377-388

2021

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mTOR inhibition downregulates glucose-6-phosphate dehydrogenase and induces ROS-dependent death in T-cell acute lymphoblastic leukemia cells

Redox biology, 2022-05, Vol.51, p.102268-102268, Article 102268

2022

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Dissecting molecular mechanisms of resistance to NOTCH1-targeted therapy in T-cell acute lymphoblastic leukemia xenografts

Haematologica (Roma), 2020-05, Vol.105 (5), p.1317-1328

2020

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Repurposing Verapamil to Enhance Killing of T-ALL Cells by the mTOR Inhibitor Everolimus

Antioxidants, 2023-03, Vol.12 (3), p.625

2023

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Anti-VEGF therapy selects for clones resistant to glucose starvation in ovarian cancer xenografts

Journal of experimental & clinical cancer research, 2023-08, Vol.42 (1), p.196-196, Article 196

2023

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WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia

Haematologica (Roma), 2018-02, Vol.103 (2), p.266-277

2018

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miR-22-3p Negatively Affects Tumor Progression in T-Cell Acute Lymphoblastic Leukemia

Cells (Basel, Switzerland), 2020-07, Vol.9 (7), p.1726

2020

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Targeting NOTCH1 in combination with antimetabolite drugs prolongs life span in relapsed pediatric and adult T-acute lymphoblastic leukemia xenografts

Experimental hematology & oncology, 2023-09, Vol.12 (1), p.1-76, Article 76

2023

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Identification of Genes Selectively Regulated by IFNs in Endothelial Cells

Journal of Immunology, 2007-01, Vol.178 (2), p.1122-1135

2007

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Interruption of Tumor Dormancy by a Transient Angiogenic Burst within the Tumor Microenvironment

Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (11), p.4216-4221

2006

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Ligand-driven activation of the Notch pathway in T-all and solid tumors: Why Not(ch)?

Cell cycle (Georgetown, Tex.), 2010-01, Vol.9 (1), p.80-85

2010

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A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia

Cells (Basel, Switzerland), 2018-10, Vol.7 (10), p.160

2018

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Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia

Blood, 2017-12, Vol.130 (25), p.2750-2761

2017

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Histone deacetylase 6 controls Notch3 trafficking and degradation in T-cell acute lymphoblastic leukemia cells

Oncogene, 2018-07, Vol.37 (28), p.3839-3851

2018

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The Transcription Factors NFATc1 and NFATc2 Control Glucocorticoid Resistance in Pediatric T-Cell Acute Lymphoblastic Leukemia

Blood, 2023-11, Vol.142 (Supplement 1), p.420-420

2023

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A novel and highly effective mitochondrial uncoupling drug in T-cell leukemia

Blood, 2021-10, Vol.138 (15), p.1317-1330

2021

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AKR1C enzymes sustain therapy resistance in paediatric T-ALL

British journal of cancer, 2018-04, Vol.118 (7), p.985-994

2018

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Cross-talk between Tumor and Endothelial Cells Involving the Notch3-Dll4 Interaction Marks Escape from Tumor Dormancy

Cancer research (Chicago, Ill.), 2009-02, Vol.69 (4), p.1314-1323

2009

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DLL4 regulates NOTCH signaling and growth of T acute lymphoblastic leukemia cells in NOD/SCID mice

Carcinogenesis (New York), 2015-01, Vol.36 (1), p.115-121

2015

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Antitumor Activity of the Xanthonoside XGAc in Triple-Negative Breast, Ovarian and Pancreatic Cancer by Inhibiting DNA Repair

Cancers, 2023-12, Vol.15 (24), p.5718

2023

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STR Profiling of HTLV-1-Infected Cell Lines

Methods in molecular biology (Clifton, N.J.), 2017, Vol.1582, p.143

2017

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Selective killing of human T-ALL cells: an integrated approach targeting redox homeostasis and the OMA1/OPA1 axis

Cell death & disease, 2018-08, Vol.9 (8), p.822-11, Article 822

2018

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Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures

SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia

mTOR inhibition downregulates glucose-6-phosphate dehydrogenase and induces ROS-dependent death in T-cell acute lymphoblastic leukemia cells

Dissecting molecular mechanisms of resistance to NOTCH1-targeted therapy in T-cell acute lymphoblastic leukemia xenografts

Repurposing Verapamil to Enhance Killing of T-ALL Cells by the mTOR Inhibitor Everolimus

Anti-VEGF therapy selects for clones resistant to glucose starvation in ovarian cancer xenografts

WT1 loss attenuates the TP53-induced DNA damage response in T-cell acute lymphoblastic leukemia

miR-22-3p Negatively Affects Tumor Progression in T-Cell Acute Lymphoblastic Leukemia

Targeting NOTCH1 in combination with antimetabolite drugs prolongs life span in relapsed pediatric and adult T-acute lymphoblastic leukemia xenografts

Identification of Genes Selectively Regulated by IFNs in Endothelial Cells

Interruption of Tumor Dormancy by a Transient Angiogenic Burst within the Tumor Microenvironment

Ligand-driven activation of the Notch pathway in T-all and solid tumors: Why Not(ch)?

A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia

Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia

Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL

Histone deacetylase 6 controls Notch3 trafficking and degradation in T-cell acute lymphoblastic leukemia cells

The Transcription Factors NFATc1 and NFATc2 Control Glucocorticoid Resistance in Pediatric T-Cell Acute Lymphoblastic Leukemia

Correction: Notch3-regulated microRNAs impair CXCR4-dependent maturation of thymocytes allowing maintenance and progression of T-ALL

A novel and highly effective mitochondrial uncoupling drug in T-cell leukemia

AKR1C enzymes sustain therapy resistance in paediatric T-ALL

Cross-talk between Tumor and Endothelial Cells Involving the Notch3-Dll4 Interaction Marks Escape from Tumor Dormancy

DLL4 regulates NOTCH signaling and growth of T acute lymphoblastic leukemia cells in NOD/SCID mice

Antitumor Activity of the Xanthonoside XGAc in Triple-Negative Breast, Ovarian and Pancreatic Cancer by Inhibiting DNA Repair

STR Profiling of HTLV-1-Infected Cell Lines

Selective killing of human T-ALL cells: an integrated approach targeting redox homeostasis and the OMA1/OPA1 axis

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