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mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy

Oncogene, 2018-09, Vol.37 (38), p.5205-5220

2018

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Melatonin induces apoptotic cell death through Bim stabilization by Sp1‐mediated OTUD1 upregulation

Journal of pineal research, 2022-01, Vol.72 (1), p.e12781-n/a

2022

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Magnolol Enhances the Therapeutic Effects of TRAIL through DR5 Upregulation and Downregulation of c-FLIP and Mcl-1 Proteins in Cancer Cells

Molecules (Basel, Switzerland), 2020-10, Vol.25 (19), p.4591

2020

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Melatonin-mediated Bim up-regulation and cyclooxygenase-2 (COX-2) down-regulation enhances tunicamycin-induced apoptosis in MDA-MB-231 cells

Journal of pineal research, 2015-04, Vol.58 (3), p.310-320

2015

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Curcumin significantly enhances dual PI3K/Akt and mTOR inhibitor NVP-BEZ235-induced apoptosis in human renal carcinoma Caki cells through down-regulation of p53-dependent Bcl-2 expression and inhibition of Mcl-1 protein stability

PloS one, 2014-04, Vol.9 (4), p.e95588

2014

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Hispidulin Inhibits Mast Cell-Mediated Allergic Inflammation through Down-Regulation of Histamine Release and Inflammatory Cytokines

Molecules (Basel, Switzerland), 2019-06, Vol.24 (11), p.2131

2019

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Corosolic Acid Induces Non-Apoptotic Cell Death through Generation of Lipid Reactive Oxygen Species Production in Human Renal Carcinoma Caki Cells

International journal of molecular sciences, 2018-04, Vol.19 (5), p.1309

2018

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Induction of Lysosomal Membrane Permeabilization Is a Major Event of FTY720-Mediated Non-Apoptotic Cell Death in Human Glioma Cells

Cancers, 2020-11, Vol.12 (11), p.3388

2020

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Inhibition of Drp1 Sensitizes Cancer Cells to Cisplatin-Induced Apoptosis through Transcriptional Inhibition of c-FLIP Expression

Molecules (Basel, Switzerland), 2020-12, Vol.25 (24), p.5793

2020

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Cathepsin D as a potential therapeutic target to enhance anticancer drug-induced apoptosis via RNF183-mediated destabilization of Bcl-xL in cancer cells

Cell death & disease, 2022-02, Vol.13 (2), p.115-115, Article 115

2022

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Z-FL-COCHO, a cathepsin S inhibitor, enhances oxaliplatin-mediated apoptosis through the induction of endoplasmic reticulum stress

Experimental and Molecular Medicine, 2018, 50(0), , pp.1-11

2018

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Premature ventricular contraction increases the risk of heart failure and ventricular tachyarrhythmia

Scientific reports, 2021-06, Vol.11 (1), p.12698-12698, Article 12698

2021

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Inhibition of cathepsin K sensitizes oxaliplatin-induced apoptotic cell death by Bax upregulation through OTUB1-mediated p53 stabilization in vitro and in vivo

Oncogene, 2022-01, Vol.41 (4), p.550-559

2022

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Cepharanthine Enhances TRAIL-Mediated Apoptosis Through STAMBPL1-Mediated Downregulation of Survivin Expression in Renal Carcinoma Cells

International journal of molecular sciences, 2018-10, Vol.19 (10), p.3280

2018

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Axl Inhibitor R428 Enhances TRAIL-Mediated Apoptosis Through Downregulation of c-FLIP and Survivin Expression in Renal Carcinoma

International journal of molecular sciences, 2019-07, Vol.20 (13), p.3253

2019

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Itch and autophagy-mediated NF-κB activation contributes to inhibition of cathepsin D-induced sensitizing effect on anticancer drugs

Cell death & disease, 2022-06, Vol.13 (6), p.552-552, Article 552

2022

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WP1130 Enhances TRAIL-Induced Apoptosis through USP9X-Dependent miR-708-Mediated Downregulation of c-FLIP

Cancers, 2019-03, Vol.11 (3), p.344

2019

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Elucidation for modulation of death receptor (DR) 5 to strengthen apoptotic signals in cancer cells

Archives of Pharmacal Research, 2019, 42(1), , pp.88-100

2019

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Inhibitory effects of melatonin on the lipopolysaccharide-induced CC chemokine expression in BV2 murine microglial cells are mediated by suppression of Akt-induced NF-κB and STAT/GAS activity

Journal of pineal research, 2012-04, Vol.52 (3), p.296-304

2012

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Withaferin A inhibits JAK/STAT3 signaling and induces apoptosis of human renal carcinoma Caki cells

Biochemical and biophysical research communications, 2012-10, Vol.427 (1), p.24-29

2012

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NOX4-mediated ROS production induces apoptotic cell death via down-regulation of c-FLIP and Mcl-1 expression in combined treatment with thioridazine and curcumin

Redox biology, 2017-10, Vol.13 (C), p.608-622

2017

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Transcriptional and post-translational regulation of Bim controls apoptosis in melatonin-treated human renal cancer Caki cells

Journal of pineal research, 2014-01, Vol.56 (1), p.97-106

2014

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Cathepsin K inhibition-induced mitochondrial ROS enhances sensitivity of cancer cells to anti-cancer drugs through USP27x-mediated Bim protein stabilization

Redox biology, 2020-02, Vol.30, p.101422, Article 101422

2020

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Chloroquine enhances TRAIL-mediated apoptosis through up-regulation of DR5 by stabilization of mRNA and protein in cancer cells

Scientific reports, 2016-03, Vol.6 (1), p.22921, Article 22921

2016

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Garcinol Enhances TRAIL-Induced Apoptotic Cell Death through Up-Regulation of DR5 and Down-Regulation of c-FLIP Expression

Molecules (Basel, Switzerland), 2018-07, Vol.23 (7), p.1614

2018

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mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy

Melatonin induces apoptotic cell death through Bim stabilization by Sp1‐mediated OTUD1 upregulation

Magnolol Enhances the Therapeutic Effects of TRAIL through DR5 Upregulation and Downregulation of c-FLIP and Mcl-1 Proteins in Cancer Cells

Melatonin-mediated Bim up-regulation and cyclooxygenase-2 (COX-2) down-regulation enhances tunicamycin-induced apoptosis in MDA-MB-231 cells

Curcumin significantly enhances dual PI3K/Akt and mTOR inhibitor NVP-BEZ235-induced apoptosis in human renal carcinoma Caki cells through down-regulation of p53-dependent Bcl-2 expression and inhibition of Mcl-1 protein stability

Hispidulin Inhibits Mast Cell-Mediated Allergic Inflammation through Down-Regulation of Histamine Release and Inflammatory Cytokines

Corosolic Acid Induces Non-Apoptotic Cell Death through Generation of Lipid Reactive Oxygen Species Production in Human Renal Carcinoma Caki Cells

Induction of Lysosomal Membrane Permeabilization Is a Major Event of FTY720-Mediated Non-Apoptotic Cell Death in Human Glioma Cells

Inhibition of Drp1 Sensitizes Cancer Cells to Cisplatin-Induced Apoptosis through Transcriptional Inhibition of c-FLIP Expression

Cathepsin D as a potential therapeutic target to enhance anticancer drug-induced apoptosis via RNF183-mediated destabilization of Bcl-xL in cancer cells

Z-FL-COCHO, a cathepsin S inhibitor, enhances oxaliplatin-mediated apoptosis through the induction of endoplasmic reticulum stress

Premature ventricular contraction increases the risk of heart failure and ventricular tachyarrhythmia

Inhibition of cathepsin K sensitizes oxaliplatin-induced apoptotic cell death by Bax upregulation through OTUB1-mediated p53 stabilization in vitro and in vivo

Cepharanthine Enhances TRAIL-Mediated Apoptosis Through STAMBPL1-Mediated Downregulation of Survivin Expression in Renal Carcinoma Cells

Axl Inhibitor R428 Enhances TRAIL-Mediated Apoptosis Through Downregulation of c-FLIP and Survivin Expression in Renal Carcinoma

Itch and autophagy-mediated NF-κB activation contributes to inhibition of cathepsin D-induced sensitizing effect on anticancer drugs

WP1130 Enhances TRAIL-Induced Apoptosis through USP9X-Dependent miR-708-Mediated Downregulation of c-FLIP

Elucidation for modulation of death receptor (DR) 5 to strengthen apoptotic signals in cancer cells

Inhibitory effects of melatonin on the lipopolysaccharide-induced CC chemokine expression in BV2 murine microglial cells are mediated by suppression of Akt-induced NF-κB and STAT/GAS activity

Withaferin A inhibits JAK/STAT3 signaling and induces apoptosis of human renal carcinoma Caki cells

NOX4-mediated ROS production induces apoptotic cell death via down-regulation of c-FLIP and Mcl-1 expression in combined treatment with thioridazine and curcumin

Transcriptional and post-translational regulation of Bim controls apoptosis in melatonin-treated human renal cancer Caki cells

Cathepsin K inhibition-induced mitochondrial ROS enhances sensitivity of cancer cells to anti-cancer drugs through USP27x-mediated Bim protein stabilization

Chloroquine enhances TRAIL-mediated apoptosis through up-regulation of DR5 by stabilization of mRNA and protein in cancer cells

Garcinol Enhances TRAIL-Induced Apoptotic Cell Death through Up-Regulation of DR5 and Down-Regulation of c-FLIP Expression

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