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Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia

PloS one, 2017-01, Vol.12 (1), p.e0169128

2017

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Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes

Cancer cell, 2011-07, Vol.20 (1), p.92-103

2011

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Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells

Cancer research (Chicago, Ill.), 2007-07, Vol.67 (13), p.6278-6285

2007

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870 CoREST inhibition by TNG260 increases expression of immunomodulatory genes in STK11-mutant cancer and sensitizes to immune checkpoint blockade

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A969-A969

2023

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RelB NF-κB Represses Estrogen Receptor α Expression via Induction of the Zinc Finger Protein Blimp1

Molecular and Cellular Biology, 2009-07, Vol.29 (14), p.3832-3844

2009

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A Loss-of-Function Polymorphism in the Propeptide Domain of the LOX Gene and Breast Cancer

Cancer research (Chicago, Ill.), 2009-08, Vol.69 (16), p.6685-6693

2009

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The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer

Cancer research (Chicago, Ill.), 2007-02, Vol.67 (3), p.1105-1112

2007

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NF-κB and epithelial to mesenchymal transition of cancer

Journal of cellular biochemistry, 2008-06, Vol.104 (3), p.733-744

2008

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Abstract 1905: In vivo CRISPR screen identifies tumor suppressors as drivers of tumor cell-intrinsic immune evasion

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1905-1905

2021

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Abstract 2892: EGLN1 is a synthetic lethal target in ARID1A -mutant ovarian cancer

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2892-2892

2018

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The Lysyl Oxidase Pro-peptide Attenuates Fibronectin-mediated Activation of Focal Adhesion Kinase and p130Cas in Breast Cancer Cells

The Journal of biological chemistry, 2009-01, Vol.284 (3), p.1385-1393

2009

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Abstract 5372: Novel and selective inhibitors of histone deacetylases (HDAC) 1 and 2 significantly enhance the activity of the DNA methyltransferase inhibitor azacitidine in acute myeloid leukemia (AML)

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.5372-5372

2015

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Abstract B84: Novel and selective inhibitors of histone deacetylases (HDAC) 1 and 2 significantly enhance the activity of the DNA methyltransferase inhibitor azacitidine in acute myeloid leukemia (AML)

Molecular cancer therapeutics, 2015-12, Vol.14 (12_Supplement_2), p.B84-B84

2015

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Abstract 4724: Novel and selective inhibitors of histone deacetylases (HDAC) 1 and 2 synergize with DNA methyltransferase inhibitor azacitidine in acute myeloid leukemia (AML)

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4724-4724

2016

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Abstract ND12: TNG260: A novel, orally active, CoREST-selective deacetylase inhibitor for the treatment of STK11-mutant cancers

Cancer research (Chicago, Ill.), 2023-05, Vol.83 (7_Supplement), p.ND12-ND12

2023

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444 TNG260, a CoREST-selective deacetylase inhibitor, reverses anti-PD1 resistance driven by loss of STK11

Journal for immunotherapy of cancer, 2022-11, Vol.10 (Suppl 2), p.A464-A464

2022

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Abstract C221: A genome-wide RNA interference screen identifies synthetic lethal interactions with the BRAF oncogene

Molecular cancer therapeutics, 2013-11, Vol.12 (11_Supplement), p.C221-C221

2013

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Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis

Journal of cellular biochemistry, 2010-12, Vol.111 (5), p.1160-1168

2010

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The Lysyl Oxidase Pro-peptide Attenuates Fibronectin-mediated Activation of Focal Adhesion Kinase and p130Cas in Breast Cancer CellsS

The Journal of biological chemistry, 2009-01, Vol.284 (3), p.1385-1393

2009

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Pro-invasion metastasis drivers in early stage melanoma are oncogenes

Cancer cell, 2011-07, Vol.20 (1), p.92-103

2011

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Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes

Cancer cell, 2011, Vol.20 (2), p.277-277

2011

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The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of breast cancer cells and is impaired in a polymorphic variant

Min, Chengyin

2009

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RelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1: RelB represses ERα transcription by inducing Blimp

Molecular and cellular biology, 2009-07, Vol.29 (14), p.3832-44

2009

Volltextzugriff (PDF)

RelB NF-B Represses Estrogen Receptor Expression via Induction of the Zinc Finger Protein Blimp1

Molecular and cellular biology, 2009-07, Vol.29 (14), p.3832-3844

2009

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ABO sequence analysis in an AB type with anti-B patient

Chinese medical journal, 2014, Vol.127 (5), p.971-972

2014

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Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia

Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes

Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells

870 CoREST inhibition by TNG260 increases expression of immunomodulatory genes in STK11-mutant cancer and sensitizes to immune checkpoint blockade

RelB NF-κB Represses Estrogen Receptor α Expression via Induction of the Zinc Finger Protein Blimp1

A Loss-of-Function Polymorphism in the Propeptide Domain of the LOX Gene and Breast Cancer

The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer

NF-κB and epithelial to mesenchymal transition of cancer

Abstract 1905: In vivo CRISPR screen identifies tumor suppressors as drivers of tumor cell-intrinsic immune evasion

Abstract 2892: EGLN1 is a synthetic lethal target in ARID1A -mutant ovarian cancer

The Lysyl Oxidase Pro-peptide Attenuates Fibronectin-mediated Activation of Focal Adhesion Kinase and p130Cas in Breast Cancer Cells

Abstract 5372: Novel and selective inhibitors of histone deacetylases (HDAC) 1 and 2 significantly enhance the activity of the DNA methyltransferase inhibitor azacitidine in acute myeloid leukemia (AML)

Abstract B84: Novel and selective inhibitors of histone deacetylases (HDAC) 1 and 2 significantly enhance the activity of the DNA methyltransferase inhibitor azacitidine in acute myeloid leukemia (AML)

Abstract 4724: Novel and selective inhibitors of histone deacetylases (HDAC) 1 and 2 synergize with DNA methyltransferase inhibitor azacitidine in acute myeloid leukemia (AML)

Abstract ND12: TNG260: A novel, orally active, CoREST-selective deacetylase inhibitor for the treatment of STK11-mutant cancers

444 TNG260, a CoREST-selective deacetylase inhibitor, reverses anti-PD1 resistance driven by loss of STK11

Abstract C221: A genome-wide RNA interference screen identifies synthetic lethal interactions with the BRAF oncogene

Lysyl oxidase propeptide sensitizes pancreatic and breast cancer cells to doxorubicin-induced apoptosis

The Lysyl Oxidase Pro-peptide Attenuates Fibronectin-mediated Activation of Focal Adhesion Kinase and p130Cas in Breast Cancer CellsS

Pro-invasion metastasis drivers in early stage melanoma are oncogenes

Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes

The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of breast cancer cells and is impaired in a polymorphic variant

RelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1: RelB represses ERα transcription by inducing Blimp

RelB NF-B Represses Estrogen Receptor Expression via Induction of the Zinc Finger Protein Blimp1

ABO sequence analysis in an AB type with anti-B patient

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