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Cellular regulation of SIRT1

Current pharmaceutical design, 2009, Vol.15 (1), p.39-44

Milner, Jo

2009

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Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival

Cancer research (Chicago, Ill.), 2005-11, Vol.65 (22), p.10457-10463

2005

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Basal cancer cell survival involves JNK2 suppression of a novel JNK1/c-Jun/Bcl-3 apoptotic network

PloS one, 2009-10, Vol.4 (10), p.e7305-e7305

2009

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JNK2-dependent regulation of SIRT1 protein stability

Cell cycle (Georgetown, Tex.), 2008-10, Vol.7 (19), p.3091-3097

2008

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Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells

Genes & development, 2003-04, Vol.17 (7), p.832-837

2003

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Single-Stranded DNA Mimicry in the p53 Transactivation Domain Interaction with Replication Protein A

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (43), p.15412-15417

2005

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Aurora A mediates cross-talk between N- and C-terminal post-translational modifications of p53

Cancer biology & therapy, 2011-12, Vol.12 (12), p.1059-1068

2011

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RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure

Molecular therapy. Nucleic acids, 2014-01, Vol.3 (1), p.e141-e141, Article e141

2014

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SIRT1, p53 and mitotic chromosomes

Cell cycle (Georgetown, Tex.), 2011-09, Vol.10 (18), p.3049-3049

2011

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SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53

PloS one, 2010-10, Vol.5 (10), p.e13502-e13502

2010

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A Deacetylase-Deficient SIRT1 Variant Opposes Full-Length SIRT1 in Regulating Tumor Suppressor p53 and Governs Expression of Cancer-Related Genes

Molecular and Cellular Biology, 2012-02, Vol.32 (3), p.704-716

2012

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Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity

Open biology, 2013-11, Vol.3 (11), p.130130-130130

2013

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p53 regulates LIF expression in human medulloblastoma cells

Journal of neuro-oncology, 2010-05, Vol.97 (3), p.373-382

2010

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Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference

Oncogene, 2002-09, Vol.21 (39), p.6041-6048

2002

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Confronting the Human Rights Act: Contemporary Themes and Perspectives

1, 2012

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SIRT3 is Pro-Apoptotic and Participates in Distinct Basal Apoptotic Pathways

Cell cycle (Georgetown, Tex.), 2007-11, Vol.6 (21), p.2669-2677

2007

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Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

The EMBO journal, 2003-11, Vol.22 (22), p.6068-6077

2003

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Influence of tetramerisation on site-specific post-translational modifications of p53: comparison of human and murine p53 tumour suppressor protein

Cancer biology & therapy, 2008-09, Vol.7 (9), p.1481-1489

2008

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SIRT1, metabolism and cancer

Current opinion in oncology, 2012-01, Vol.24 (1), p.68-75

2012

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An ATP/ADP-Dependent Molecular Switch Regulates the Stability of p53-DNA Complexes

Molecular and Cellular Biology, 1999-11, Vol.19 (11), p.7501-7510

1999

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p53: Guardian of a Genome's Guardian?

Cell cycle (Georgetown, Tex.), 2003-01, Vol.2 (1), p.20-21

2003

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Mutations of the p53 gene in canine lymphoma and evidence for germ line p53 mutations in the dog

Oncogene, 1998-01, Vol.16 (2), p.249-255

1998

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A conformation hypothesis for the suppressor and promoter functions of p53 in cell growth control and in cancer

Proceedings of the Royal Society. B, Biological sciences, 1991-08, Vol.245 (1313), p.139-145

Milner, J

1991

Volltextzugriff (PDF)

Isolation of canine p53 cDNA and detailed characterization of the full length canine p53 protein

Oncogene, 1998-02, Vol.16 (8), p.1077-1084

1998

Volltextzugriff (PDF)

P53 autoantibodies in 1006 patients followed up for breast cancer

Breast cancer research : BCR, 2000, Vol.2 (6), p.438-443, Article 438

2000

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Cellular regulation of SIRT1

Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival

Basal cancer cell survival involves JNK2 suppression of a novel JNK1/c-Jun/Bcl-3 apoptotic network

JNK2-dependent regulation of SIRT1 protein stability

Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells

Single-Stranded DNA Mimicry in the p53 Transactivation Domain Interaction with Replication Protein A

Aurora A mediates cross-talk between N- and C-terminal post-translational modifications of p53

RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure

SIRT1, p53 and mitotic chromosomes

SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53

A Deacetylase-Deficient SIRT1 Variant Opposes Full-Length SIRT1 in Regulating Tumor Suppressor p53 and Governs Expression of Cancer-Related Genes

Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity

p53 regulates LIF expression in human medulloblastoma cells

Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference

Confronting the Human Rights Act: Contemporary Themes and Perspectives

SIRT3 is Pro-Apoptotic and Participates in Distinct Basal Apoptotic Pathways

Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

Influence of tetramerisation on site-specific post-translational modifications of p53: comparison of human and murine p53 tumour suppressor protein

SIRT1, metabolism and cancer

An ATP/ADP-Dependent Molecular Switch Regulates the Stability of p53-DNA Complexes

p53: Guardian of a Genome's Guardian?

Mutations of the p53 gene in canine lymphoma and evidence for germ line p53 mutations in the dog

A conformation hypothesis for the suppressor and promoter functions of p53 in cell growth control and in cancer

Isolation of canine p53 cDNA and detailed characterization of the full length canine p53 protein

P53 autoantibodies in 1006 patients followed up for breast cancer

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