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The Anti-inflammatory Protein TSG-6 Regulates Chemokine Function by Inhibiting Chemokine/Glycosaminoglycan Interactions

The Journal of biological chemistry, 2016-06, Vol.291 (24), p.12627-12640

2016

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TSG-6: A multifunctional protein with anti-inflammatory and tissue-protective properties

Matrix biology, 2019-05, Vol.78-79, p.60-83

2019

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Coregulation in human leukocytes of the long pentraxin PTX3 and TSG-6

Journal of leukocyte biology, 2009-07, Vol.86 (1), p.123-132

2009

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TSG-6 Regulates Bone Remodeling through Inhibition of Osteoblastogenesis and Osteoclast Activation

The Journal of biological chemistry, 2008-09, Vol.283 (38), p.25952-25962

2008

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Chemical modification of hyaluronan oligosaccharides differentially modulates hyaluronan-hyaladherin interactions

The Journal of biological chemistry, 2024-08, p.107668

2024

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TSG-6 inhibits neutrophil migration via direct interaction with the chemokine CXCL8

The Journal of immunology (1950), 2014-03, Vol.192 (5), p.2177-2185

2014

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TSG-6: a multifunctional protein associated with inflammation

Journal of cell science, 2003-05, Vol.116 (Pt 10), p.1863-1873

2003

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The recombinant Link module of human TSG-6 suppresses cartilage damage in models of osteoarthritis: A potential disease-modifying OA drug

Osteoarthritis and cartilage, 2023-10, Vol.31 (10), p.1353-1364

2023

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Inter-alpha-trypsin inhibitor (IαI) and hyaluronan modifications enhance the innate immune response to influenza virus in the lung

Matrix biology, 2024-02, Vol.126, p.25-42

2024

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Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation

The Journal of biological chemistry, 2020-04, Vol.295 (16), p.5278-5291

2020

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Incorporation of Pentraxin 3 into Hyaluronan Matrices Is Tightly Regulated and Promotes Matrix Cross-linking

The Journal of biological chemistry, 2014-10, Vol.289 (44), p.30481-30498

2014

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The Link module of human TSG-6 (Link_TSG6) promotes wound healing, suppresses inflammation and improves glandular function in mouse models of Dry Eye Disease

The ocular surface, 2022-04, Vol.24, p.40-50

2022

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Metal Ion-dependent Heavy Chain Transfer Activity of TSG-6 Mediates Assembly of the Cumulus-Oocyte Matrix

The Journal of biological chemistry, 2015-11, Vol.290 (48), p.28708-28723

2015

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Inter-α-inhibitor Impairs TSG-6-induced Hyaluronan Cross-linking

The Journal of biological chemistry, 2013-10, Vol.288 (41), p.29642-29653

2013

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A refined model for the TSG-6 link module in complex with hyaluronan: use of defined oligosaccharides to probe structure and function

The Journal of biological chemistry, 2014-02, Vol.289 (9), p.5619-5634

2014

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Oocyte-specific ablation of N- and O-glycans alters cumulus cell signalling and extracellular matrix composition

Reproduction fertility and development, 2019-03, Vol.31 (3), p.529

2019

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Molecular analysis of the cumulus matrix: insights from mice with O-glycan-deficient oocytes

Reproduction (Cambridge, England), 2015-05, Vol.149 (5), p.533-543

2015

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TSG‐6 inhibits osteoclast activity via an autocrine mechanism and is functionally synergistic with osteoprotegerin

Arthritis & rheumatology (Hoboken, N.J.), 2011-04, Vol.63 (4), p.1034-1043

2011

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Characterization of complexes formed between TSG-6 and inter-alpha-inhibitor that act as intermediates in the covalent transfer of heavy chains onto hyaluronan

The Journal of biological chemistry, 2005-07, Vol.280 (27), p.25674

2005

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Modulation of tumor necrosis factor-stimulated gene-6 (TSG-6) expression in human endometrium

Archives of gynecology and obstetrics, 2014-04, Vol.289 (4), p.893-901

2014

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TSG-6 potentiates the antitissue kallikrein activity of inter-alpha-inhibitor through bikunin release

American journal of respiratory cell and molecular biology, 2007-01, Vol.36 (1), p.20-31

2007

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Characterization of the interaction between tumor necrosis factor-stimulated gene-6 and heparin: implications for the inhibition of plasmin in extracellular matrix microenvironments

The Journal of biological chemistry, 2005-07, Vol.280 (29), p.27044-27055

2005

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The Link Module from Human TSG-6 Inhibits Neutrophil Migration in a Hyaluronan- and Inter-α-inhibitor-independent Manner

The Journal of biological chemistry, 2002-12, Vol.277 (52), p.51068-51076

2002

Volltextzugriff (PDF)

Heat shock protein 70 (Hsp70) stimulates proliferation and cytolytic activity of natural killer cells

Experimental hematology, 1999-11, Vol.27 (11), p.1627-1636

1999

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Multi-factorial modulation of IGD motogenic potential in MSF (Migration Stimulating Factor)

Experimental cell research, 2010-09, Vol.316 (15), p.2465-2476

2010

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The Anti-inflammatory Protein TSG-6 Regulates Chemokine Function by Inhibiting Chemokine/Glycosaminoglycan Interactions

TSG-6: A multifunctional protein with anti-inflammatory and tissue-protective properties

Coregulation in human leukocytes of the long pentraxin PTX3 and TSG-6

TSG-6 Regulates Bone Remodeling through Inhibition of Osteoblastogenesis and Osteoclast Activation

Chemical modification of hyaluronan oligosaccharides differentially modulates hyaluronan-hyaladherin interactions

TSG-6 inhibits neutrophil migration via direct interaction with the chemokine CXCL8

TSG-6: a multifunctional protein associated with inflammation

The recombinant Link module of human TSG-6 suppresses cartilage damage in models of osteoarthritis: A potential disease-modifying OA drug

Inter-alpha-trypsin inhibitor (IαI) and hyaluronan modifications enhance the innate immune response to influenza virus in the lung

Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation

Incorporation of Pentraxin 3 into Hyaluronan Matrices Is Tightly Regulated and Promotes Matrix Cross-linking

The Link module of human TSG-6 (Link_TSG6) promotes wound healing, suppresses inflammation and improves glandular function in mouse models of Dry Eye Disease

Metal Ion-dependent Heavy Chain Transfer Activity of TSG-6 Mediates Assembly of the Cumulus-Oocyte Matrix

Inter-α-inhibitor Impairs TSG-6-induced Hyaluronan Cross-linking

A refined model for the TSG-6 link module in complex with hyaluronan: use of defined oligosaccharides to probe structure and function

Oocyte-specific ablation of N- and O-glycans alters cumulus cell signalling and extracellular matrix composition

Molecular analysis of the cumulus matrix: insights from mice with O-glycan-deficient oocytes

TSG‐6 inhibits osteoclast activity via an autocrine mechanism and is functionally synergistic with osteoprotegerin

Characterization of complexes formed between TSG-6 and inter-alpha-inhibitor that act as intermediates in the covalent transfer of heavy chains onto hyaluronan

Modulation of tumor necrosis factor-stimulated gene-6 (TSG-6) expression in human endometrium

TSG-6 potentiates the antitissue kallikrein activity of inter-alpha-inhibitor through bikunin release

Characterization of the interaction between tumor necrosis factor-stimulated gene-6 and heparin: implications for the inhibition of plasmin in extracellular matrix microenvironments

The Link Module from Human TSG-6 Inhibits Neutrophil Migration in a Hyaluronan- and Inter-α-inhibitor-independent Manner

Heat shock protein 70 (Hsp70) stimulates proliferation and cytolytic activity of natural killer cells

Multi-factorial modulation of IGD motogenic potential in MSF (Migration Stimulating Factor)

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