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Structural mechanism of trimeric HIV-1 envelope glycoprotein activation

PLoS pathogens, 2012-07, Vol.8 (7), p.e1002797-e1002797

2012

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2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor

Science (American Association for the Advancement of Science), 2015-06, Vol.348 (6239), p.1147-1151

2015

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Cryo-electron tomography of bacteria: progress, challenges and future prospects

Nature reviews. Microbiology, 2009-09, Vol.7 (9), p.666-675

2009

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Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy

Nature structural & molecular biology, 2013-12, Vol.20 (12), p.1352-1357

2013

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Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery

Cell, 2016-06, Vol.165 (7), p.1698-1707

2016

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2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6275), p.871-875

2016

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Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure

PLoS pathogens, 2010-12, Vol.6 (12), p.e1001249

2010

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Atomic Resolution Cryo-EM Structure of β-Galactosidase

Structure (London), 2018-06, Vol.26 (6), p.848-856.e3

2018

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Cryo‐electron microscopy – a primer for the non‐microscopist

The FEBS journal, 2013-01, Vol.280 (1), p.28-45

2013

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Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (28), p.11440-11445

2011

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Cryo-EM: beyond the microscope

Current opinion in structural biology, 2017-10, Vol.46, p.71-78

2017

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Resolution advances in cryo-EM enable application to drug discovery

Current opinion in structural biology, 2016-12, Vol.41, p.194-202

2016

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HIV-1 Envelope Glycoprotein Trimers Display Open Quaternary Conformation When Bound to the gp41 Membrane-Proximal External-Region-Directed Broadly Neutralizing Antibody Z13e1

Journal of Virology, 2013-06, Vol.87 (12), p.7191-7196

2013

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Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase

Molecular pharmacology, 2016-06, Vol.89 (6), p.645-651

2016

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An Extremely Active Catalyst for the Negishi Cross-Coupling Reaction

Journal of the American Chemical Society, 2004-10, Vol.126 (40), p.13028-13032

2004

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Three-Dimensional Imaging of the Highly Bent Architecture of Bdellovibrio bacteriovorus by Using Cryo-Electron Tomography

Journal of Bacteriology, 2008-04, Vol.190 (7), p.2588-2596

2008

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Spiral Architecture of the Nucleoid in Bdellovibrio bacteriovorus

Journal of Bacteriology, 2011-03, Vol.193 (6), p.1341-1350

2011

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Three-Dimensional Structures of Soluble CD4-Bound States of Trimeric Simian Immunodeficiency Virus Envelope Glycoproteins Determined by Using Cryo-Electron Tomography

Journal of Virology, 2011-12, Vol.85 (23), p.12114-12123

2011

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Data-driven approach to mitigate quality impact of hygroscopic pharmaceutical raw materials throughout the supply chain

Pharmaceutical development and technology, 2022-05, Vol.27 (5), p.511-524

2022

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Synthesis of the Hydrazinyl Pyridine Intermediate: Phase-Appropriate Delivery

Organic process research & development, 2017-09, Vol.21 (9), p.1286-1293

2017

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3D Imaging of mammalian cells with ion-abrasion scanning electron microscopy

Journal of structural biology, 2009-04, Vol.166 (1), p.1-7

2009

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Molecular Structure of a 9-MDa Icosahedral Pyruvate Dehydrogenase Subcomplex Containing the E2 and E3 Enzymes Using Cryoelectron Microscopy

The Journal of biological chemistry, 2006-02, Vol.281 (7), p.4364-4370

2006

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An Efficient and Scalable Ritter Reaction for the Synthesis of tert-Butyl Amides

Journal of organic chemistry, 2009-03, Vol.74 (5), p.2207-2209

2009

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Stoichiometry and Absolute Quantification of Proteins with Mass Spectrometry Using Fluorescent and Isotope-labeled Concatenated Peptide Standards

Molecular & cellular proteomics, 2008-02, Vol.7 (2), p.442-447

2008

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Electron tomography in nanoparticle imaging and analysis

Nanomedicine (London, England), 2008-02, Vol.3 (1), p.125-131

2008

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Structural mechanism of trimeric HIV-1 envelope glycoprotein activation

2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor

Cryo-electron tomography of bacteria: progress, challenges and future prospects

Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy

Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery

2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure

Atomic Resolution Cryo-EM Structure of β-Galactosidase

Cryo‐electron microscopy – a primer for the non‐microscopist

Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

Cryo-EM: beyond the microscope

Resolution advances in cryo-EM enable application to drug discovery

HIV-1 Envelope Glycoprotein Trimers Display Open Quaternary Conformation When Bound to the gp41 Membrane-Proximal External-Region-Directed Broadly Neutralizing Antibody Z13e1

Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase

An Extremely Active Catalyst for the Negishi Cross-Coupling Reaction

Three-Dimensional Imaging of the Highly Bent Architecture of Bdellovibrio bacteriovorus by Using Cryo-Electron Tomography

Spiral Architecture of the Nucleoid in Bdellovibrio bacteriovorus

Three-Dimensional Structures of Soluble CD4-Bound States of Trimeric Simian Immunodeficiency Virus Envelope Glycoproteins Determined by Using Cryo-Electron Tomography

Data-driven approach to mitigate quality impact of hygroscopic pharmaceutical raw materials throughout the supply chain

Synthesis of the Hydrazinyl Pyridine Intermediate: Phase-Appropriate Delivery

3D Imaging of mammalian cells with ion-abrasion scanning electron microscopy

Molecular Structure of a 9-MDa Icosahedral Pyruvate Dehydrogenase Subcomplex Containing the E2 and E3 Enzymes Using Cryoelectron Microscopy

An Efficient and Scalable Ritter Reaction for the Synthesis of tert-Butyl Amides

Stoichiometry and Absolute Quantification of Proteins with Mass Spectrometry Using Fluorescent and Isotope-labeled Concatenated Peptide Standards

Electron tomography in nanoparticle imaging and analysis

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