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Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor

Biochemical journal, 1999-03, Vol.338 ( Pt 2) (2), p.479-487

1999

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The identification of clinical candidate SB-480848 : A potent inhibitor of lipoprotein-associated phospholipase A2

Bioorganic & medicinal chemistry letters, 2003-03, Vol.13 (6), p.1067-1070

2003

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The discovery of SB-435495: A potent, orally active inhibitor of lipoprotein-associated phospholipase A2 for evaluation in man

Bioorganic & medicinal chemistry letters, 2002-09, Vol.12 (18), p.2603-2606

2002

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Potent, orally active inhibitors of lipoprotein-associated phospholipase A2: 1-(biphenylmethylamidoalkyl)-pyrimidones

Bioorganic & medicinal chemistry letters, 2002-01, Vol.12 (1), p.51-55

2002

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N-1 substituted pyrimidin-4-ones: Novel, orally active inhibitors of lipoprotein-associated phospholipase A2

Bioorganic & medicinal chemistry letters, 2000-11, Vol.10 (22), p.2557-2561

2000

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The identification of a potent, water soluble inhibitor of lipoprotein-associated phospholipase A2

Bioorganic & medicinal chemistry letters, 2001-03, Vol.11 (5), p.701-704

2001

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1-(Arylpiperazinylamidoalkyl)-pyrimidones : Orally active inhibitors of lipoprotein-associated phospholipase A2

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (14), p.1925-1929

2001

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Purine derivatives as competitive inhibitors of human erythrocyte membrane phosphatidylinositol 4-kinase

Journal of medicinal chemistry, 1990-08, Vol.33 (8), p.2073-2080

1990

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Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor

Biochemical journal, 1999-03, Vol.338 (2), p.479-487

1999

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Studies on the mechanism of action of omeprazole

Biochemical pharmacology, 1985-08, Vol.34 (16), p.2967-2973

1985

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Potent, orally active inhibitors of lipoprotein-associated phospholipase A(2): 1-(biphenylmethylamidoalkyl)-pyrimidones

Bioorganic & medicinal chemistry letters, 2002-01, Vol.12 (1), p.51

2002

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2-(alkylthio)pyrimidin-4-ones as novel, reversible inhibitors of lipoprotein-associated phospholipase A2

Bioorganic & medicinal chemistry letters, 2000-02, Vol.10 (4), p.395-398

2000

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The identification of clinical candidate SB-480848: a potent inhibitor of lipoprotein-associated phospholipase A 2

Bioorganic & medicinal chemistry letters, 2003, Vol.13 (6), p.1067-1070

2003

Volltextzugriff (PDF)

Potent, orally active inhibitors of lipoprotein-associated phospholipase A 2: 1-(biphenylmethylamidoalkyl)-pyrimidones

Bioorganic & medicinal chemistry letters, 2002, Vol.12 (1), p.51-55

2002

Volltextzugriff (PDF)

The discovery of SB-435495. A potent, orally active inhibitor of lipoprotein-associated phospholipase A(2) for evaluation in man

Bioorganic & medicinal chemistry letters, 2002-09, Vol.12 (18), p.2603-2606

2002

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The discovery of SB-435495

Bioorganic & medicinal chemistry letters, 2002-09, Vol.12 (18), p.2603-2606

2002

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Lipoprotein-Associated Phospholipase A 2 , Platelet-Activating Factor Acetylhydrolase, Is Expressed by Macrophages in Human and Rabbit Atherosclerotic Lesions

Arteriosclerosis, thrombosis, and vascular biology, 1999-12, Vol.19 (12), p.2909-2917

1999

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The discovery of SB-435495: A potent, orally active inhibitor of lipoprotein-Associated phospholipase A 2 for evaluation in man

Bioorganic & medicinal chemistry letters, 2002, Vol.12 (18), p.2603-2606

2002

Volltextzugriff (PDF)

The identification of a potent, water soluble inhibitor of lipoprotein-associated phospholipase A 2

Bioorganic & medicinal chemistry letters, 2001, Vol.11 (5), p.701-704

2001

Volltextzugriff (PDF)

1-(Arylpiperazinylamidoalkyl)-pyrimidones: orally active inhibitors of lipoprotein-associated phospholipase A 2

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (14), p.1925-1929

2001

Volltextzugriff (PDF)

2-(Alkylthio)pyrimidin-4-ones as novel, reversible inhibitors of lipoprotein-associated phospholipase A 2

Bioorganic & medicinal chemistry letters, 2000-02, Vol.10 (4), p.395-398

2000

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N-1 substituted pyrimidin-4-ones: novel, orally active inhibitors of lipoprotein-associated phospholipase A 2

Bioorganic & medicinal chemistry letters, 2000, Vol.10 (22), p.2557-2561

2000

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Evaluation and management of proteinuria and nephrotic syndrome in children: recommendations from a pediatric nephrology panel established at the National Kidney Foundation conference on proteinuria, albuminuria, risk, assessment, detection, and elimination (PARADE)

Pediatrics (Evanston), 2000-06, Vol.105 (6), p.1242-1249

2000

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Metabolic rate and vascular function are reduced in women with a family history of type 2 diabetes mellitus

Metabolism, clinical and experimental, 2008-06, Vol.57 (6), p.831-837

2008

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Characterisation of the lipoprotein structure in the St. Thomas’ Mixed Hyperlipidaemic (SMHL) rabbit

Atherosclerosis, 2005-07, Vol.181 (1), p.63-68

2005

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Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor

The identification of clinical candidate SB-480848 : A potent inhibitor of lipoprotein-associated phospholipase A2

The discovery of SB-435495: A potent, orally active inhibitor of lipoprotein-associated phospholipase A2 for evaluation in man

Potent, orally active inhibitors of lipoprotein-associated phospholipase A2: 1-(biphenylmethylamidoalkyl)-pyrimidones

N-1 substituted pyrimidin-4-ones: Novel, orally active inhibitors of lipoprotein-associated phospholipase A2

The identification of a potent, water soluble inhibitor of lipoprotein-associated phospholipase A2

1-(Arylpiperazinylamidoalkyl)-pyrimidones : Orally active inhibitors of lipoprotein-associated phospholipase A2

Purine derivatives as competitive inhibitors of human erythrocyte membrane phosphatidylinositol 4-kinase

Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor

Studies on the mechanism of action of omeprazole

Potent, orally active inhibitors of lipoprotein-associated phospholipase A(2): 1-(biphenylmethylamidoalkyl)-pyrimidones

2-(alkylthio)pyrimidin-4-ones as novel, reversible inhibitors of lipoprotein-associated phospholipase A2

The identification of clinical candidate SB-480848: a potent inhibitor of lipoprotein-associated phospholipase A 2

Potent, orally active inhibitors of lipoprotein-associated phospholipase A 2: 1-(biphenylmethylamidoalkyl)-pyrimidones

The discovery of SB-435495. A potent, orally active inhibitor of lipoprotein-associated phospholipase A(2) for evaluation in man

The discovery of SB-435495

Lipoprotein-Associated Phospholipase A 2 , Platelet-Activating Factor Acetylhydrolase, Is Expressed by Macrophages in Human and Rabbit Atherosclerotic Lesions

The discovery of SB-435495: A potent, orally active inhibitor of lipoprotein-Associated phospholipase A 2 for evaluation in man

The identification of a potent, water soluble inhibitor of lipoprotein-associated phospholipase A 2

1-(Arylpiperazinylamidoalkyl)-pyrimidones: orally active inhibitors of lipoprotein-associated phospholipase A 2

2-(Alkylthio)pyrimidin-4-ones as novel, reversible inhibitors of lipoprotein-associated phospholipase A 2

N-1 substituted pyrimidin-4-ones: novel, orally active inhibitors of lipoprotein-associated phospholipase A 2

Evaluation and management of proteinuria and nephrotic syndrome in children: recommendations from a pediatric nephrology panel established at the National Kidney Foundation conference on proteinuria, albuminuria, risk, assessment, detection, and elimination (PARADE)

Metabolic rate and vascular function are reduced in women with a family history of type 2 diabetes mellitus

Characterisation of the lipoprotein structure in the St. Thomas’ Mixed Hyperlipidaemic (SMHL) rabbit

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