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Chemokines from a Structural Perspective

International journal of molecular sciences, 2017-10, Vol.18 (10), p.2088

2017

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Galectins as Molecular Targets for Therapeutic Intervention

International journal of molecular sciences, 2018-03, Vol.19 (3), p.905

2018

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Cysteine Oxidation in Human Galectin-1 Occurs Sequentially via a Folded Intermediate to a Fully Oxidized Unfolded Form

International journal of molecular sciences, 2024-07, Vol.25 (13), p.6956

2024

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PLG-007 and Its Active Component Galactomannan-α Competitively Inhibit Enzymes That Hydrolyze Glucose Polymers

International journal of molecular sciences, 2022-07, Vol.23 (14), p.7739

2022

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Binding of polysaccharides to human galectin-3 at a noncanonical site in its carbohydrate recognition domain

Glycobiology (Oxford), 2016-01, Vol.26 (1), p.88-99

2016

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Antitumor Agent Calixarene 0118 Targets Human Galectin-1 as an Allosteric Inhibitor of Carbohydrate Binding

Journal of medicinal chemistry, 2012-06, Vol.55 (11), p.5121-5129

2012

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Intra- and intermolecular interactions of human galectin-3: assessment by full-assignment-based NMR

Glycobiology (Oxford), 2016-08, Vol.26 (8), p.888-903

2016

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An Oral Galectin Inhibitor in COVID-19-A Phase II Randomized Controlled Trial

Vaccines (Basel), 2023-03, Vol.11 (4), p.731

2023

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Molecular basis for cellular retinoic acid-binding protein 1 in modulating CaMKII activation

Frontiers in molecular biosciences, 2023-09, Vol.10, p.1268843-1268843

2023

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Structural significance of galectin design: impairment of homodimer stability by linker insertion and partial reversion by ligand presence

Protein engineering, design and selection, 2015-07, Vol.28 (7), p.199-210

2015

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The carbohydrate-binding domain on galectin-1 is more extensive for a complex glycan than for simple saccharides: implications for galectin-glycan interactions at the cell surface

Biochemical journal, 2009-06, Vol.421 (2), p.211-221

2009

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Lactose binding to human galectin-7 (p53-induced gene 1) induces long-range effects through the protein resulting in increased dimer stability and evidence for positive cooperativity

Glycobiology (Oxford), 2013-05, Vol.23 (5), p.508-523

2013

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Galectin-3 N-terminal tail prolines modulate cell activity and glycan-mediated oligomerization/phase separation

Proceedings of the National Academy of Sciences - PNAS, 2021-05, Vol.118 (19), p.1

2021

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Macromolecular assemblies of complex polysaccharides with galectin-3 and their synergistic effects on function

Biochemical journal, 2017-11, Vol.474 (22), p.3849-3868

2017

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Isomerization of proline-46 in the N-terminal tail of galectin-3 enhances T cell apoptosis via the ROS-ERK pathway

International journal of biological macromolecules, 2024-01, Vol.256 (Pt 1), p.128304-128304, Article 128304

2024

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Topsy-turvy binding of negatively charged homogalacturonan oligosaccharides to galectin-3

Glycobiology (Oxford), 2021-04, Vol.31 (3), p.341-350

2021

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Adhesion/growth-regulatory galectins tested in combination: evidence for formation of hybrids as heterodimers

Biochemical journal, 2018-03, Vol.475 (5), p.1003-1018

2018

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Chemokines and galectins form heterodimers to modulate inflammation

EMBO reports, 2020-04, Vol.21 (4), p.e47852-n/a

2020

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NMR-based insight into galectin-3 binding to endothelial cell adhesion molecule CD146: Evidence for noncanonical interactions with the lectin's CRD β-sandwich F-face

Glycobiology (Oxford), 2019-07, Vol.29 (8), p.608-618

2019

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α-galactomannan Davanat binds galectin-1 at a site different from the conventional galectin carbohydrate binding domain

Glycobiology (Oxford), 2009-09, Vol.19 (9), p.1034-1045

2009

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Novel polysaccharide binding to the N-terminal tail of galectin-3 is likely modulated by proline isomerization

Glycobiology (Oxford), 2017-11, Vol.27 (11), p.1038-1051

2017

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Galectin-3 binds selectively to the terminal, non-reducing end of β(1→4)-galactans, with overall affinity increasing with chain length

Glycobiology (Oxford), 2019-01, Vol.29 (1), p.74-84

2019

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A new regulatory mechanism for Raf kinase activation, retinoic acid-bound Crabp1

Scientific reports, 2019-07, Vol.9 (1), p.10929-12, Article 10929

2019

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Pro4 prolyl peptide bond isomerization in human galectin-7 modulates the monomer-dimer equilibrum to affect function

Biochemical journal, 2020-09, Vol.477 (17), p.3147-3165

2020

Volltextzugriff (PDF)

Structural insight into the binding of human galectins to corneal keratan sulfate, its desulfated form and related saccharides

Scientific reports, 2020-09, Vol.10 (1), p.15708-15708, Article 15708

2020

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Chemokines from a Structural Perspective

Galectins as Molecular Targets for Therapeutic Intervention

Cysteine Oxidation in Human Galectin-1 Occurs Sequentially via a Folded Intermediate to a Fully Oxidized Unfolded Form

PLG-007 and Its Active Component Galactomannan-α Competitively Inhibit Enzymes That Hydrolyze Glucose Polymers

Binding of polysaccharides to human galectin-3 at a noncanonical site in its carbohydrate recognition domain

Antitumor Agent Calixarene 0118 Targets Human Galectin-1 as an Allosteric Inhibitor of Carbohydrate Binding

Intra- and intermolecular interactions of human galectin-3: assessment by full-assignment-based NMR

An Oral Galectin Inhibitor in COVID-19-A Phase II Randomized Controlled Trial

Molecular basis for cellular retinoic acid-binding protein 1 in modulating CaMKII activation

Structural significance of galectin design: impairment of homodimer stability by linker insertion and partial reversion by ligand presence

The carbohydrate-binding domain on galectin-1 is more extensive for a complex glycan than for simple saccharides: implications for galectin-glycan interactions at the cell surface

Lactose binding to human galectin-7 (p53-induced gene 1) induces long-range effects through the protein resulting in increased dimer stability and evidence for positive cooperativity

Galectin-3 N-terminal tail prolines modulate cell activity and glycan-mediated oligomerization/phase separation

Macromolecular assemblies of complex polysaccharides with galectin-3 and their synergistic effects on function

Isomerization of proline-46 in the N-terminal tail of galectin-3 enhances T cell apoptosis via the ROS-ERK pathway

Topsy-turvy binding of negatively charged homogalacturonan oligosaccharides to galectin-3

Adhesion/growth-regulatory galectins tested in combination: evidence for formation of hybrids as heterodimers

Chemokines and galectins form heterodimers to modulate inflammation

NMR-based insight into galectin-3 binding to endothelial cell adhesion molecule CD146: Evidence for noncanonical interactions with the lectin's CRD β-sandwich F-face

α-galactomannan Davanat binds galectin-1 at a site different from the conventional galectin carbohydrate binding domain

Novel polysaccharide binding to the N-terminal tail of galectin-3 is likely modulated by proline isomerization

Galectin-3 binds selectively to the terminal, non-reducing end of β(1→4)-galactans, with overall affinity increasing with chain length

A new regulatory mechanism for Raf kinase activation, retinoic acid-bound Crabp1

Pro4 prolyl peptide bond isomerization in human galectin-7 modulates the monomer-dimer equilibrum to affect function

Structural insight into the binding of human galectins to corneal keratan sulfate, its desulfated form and related saccharides

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