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Dissecting the human serum antibody response to secondary dengue virus infections

PLoS neglected tropical diseases, 2017-05, Vol.11 (5), p.e0005554-e0005554

2017

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Metal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein Homodimer

Journal of the American Chemical Society, 2012-01, Vol.134 (1), p.375-385

2012

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Oligomeric state of the ZIKV E protein defines protective immune responses

Nature communications, 2019-10, Vol.10 (1), p.4606-7, Article 4606

2019

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Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma

Cancer discovery, 2014-12, Vol.4 (12), p.1418-1429

2014

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In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers

Scientific reports, 2017-07, Vol.7 (1), p.4524-8, Article 4524

2017

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Computational design of a symmetric homodimer using β-strand assembly

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (51), p.20562-20567

2011

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Nanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype

PLoS neglected tropical diseases, 2018-09, Vol.12 (9), p.e0006793

2018

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Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7

Journal of molecular biology, 2007-06, Vol.369 (2), p.498-511

2007

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Increasing Sequence Diversity with Flexible Backbone Protein Design: The Complete Redesign of a Protein Hydrophobic Core

Structure (London), 2012-06, Vol.20 (6), p.1086-1096

2012

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Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody Responses

PLoS neglected tropical diseases, 2016-10, Vol.10 (10), p.e0005071

2016

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Pseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase Inhibitors

Journal of medicinal chemistry, 2013-12, Vol.56 (23), p.9683-9692

2013

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P-glycoprotein targeted photodynamic therapy of chemoresistant tumors using recombinant Fab fragment conjugates

Biomaterials science, 2018-10, Vol.6 (11), p.3063-3074

2018

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Discovery of Macrocyclic Pyrimidines as MerTK‐Specific Inhibitors

ChemMedChem, 2017-02, Vol.12 (3), p.207-213

2017

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Evidence for MR1 Antigen Presentation to Mucosal-associated Invariant T Cells

The Journal of biological chemistry, 2005-06, Vol.280 (22), p.21183-21193

2005

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Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia

ACS medicinal chemistry letters, 2012-02, Vol.3 (2), p.129-134

2012

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Physiological temperatures reduce dimerization of dengue and Zika virus recombinant envelope proteins

The Journal of biological chemistry, 2018-06, Vol.293 (23), p.8922-8933

2018

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Optimization of Surface Display of DENV2 E Protein on a Nanoparticle to Induce Virus Specific Neutralizing Antibody Responses

Bioconjugate chemistry, 2018-05, Vol.29 (5), p.1544-1552

2018

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Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme

Molecular human reproduction, 2016-06, Vol.22 (6), p.410-426

2016

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The role of mhc polymorphism in anti-microbial resistance

Microbes and Infection, 2004-04, Vol.6 (5), p.501-512

2004

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Discovery of Mer Specific Tyrosine Kinase Inhibitors for the Treatment and Prevention of Thrombosis

Journal of medicinal chemistry, 2013-12, Vol.56 (23), p.9693-9700

2013

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Enhanced Immune Presentation of a Single-chain Major Histocompatibility Complex Class I Molecule Engineered to Optimize Linkage of a C-terminally Extended Peptide

The Journal of biological chemistry, 2003-07, Vol.278 (29), p.27105-27111

2003

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The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families

Drug metabolism reviews, 2010-02, Vol.42 (1), p.133-144

2010

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The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis

Drug metabolism and disposition, 2008-03, Vol.36 (3), p.517-522

2008

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Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors

ACS medicinal chemistry letters, 2016-12, Vol.7 (12), p.1044-1049

2016

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Functional Characterization of the Multidomain F Plasmid TraI Relaxase-Helicase

The Journal of biological chemistry, 2011-04, Vol.286 (14), p.12670-12682

2011

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Dissecting the human serum antibody response to secondary dengue virus infections

Metal-Mediated Affinity and Orientation Specificity in a Computationally Designed Protein Homodimer

Oligomeric state of the ZIKV E protein defines protective immune responses

Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma

In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers

Computational design of a symmetric homodimer using β-strand assembly

Nanoparticle delivery of a tetravalent E protein subunit vaccine induces balanced, type-specific neutralizing antibodies to each dengue virus serotype

Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7

Increasing Sequence Diversity with Flexible Backbone Protein Design: The Complete Redesign of a Protein Hydrophobic Core

Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody Responses

Pseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase Inhibitors

P-glycoprotein targeted photodynamic therapy of chemoresistant tumors using recombinant Fab fragment conjugates

Discovery of Macrocyclic Pyrimidines as MerTK‐Specific Inhibitors

Evidence for MR1 Antigen Presentation to Mucosal-associated Invariant T Cells

Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia

Physiological temperatures reduce dimerization of dengue and Zika virus recombinant envelope proteins

Optimization of Surface Display of DENV2 E Protein on a Nanoparticle to Induce Virus Specific Neutralizing Antibody Responses

Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme

The role of mhc polymorphism in anti-microbial resistance

Discovery of Mer Specific Tyrosine Kinase Inhibitors for the Treatment and Prevention of Thrombosis

Enhanced Immune Presentation of a Single-chain Major Histocompatibility Complex Class I Molecule Engineered to Optimize Linkage of a C-terminally Extended Peptide

The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families

The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis

Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors

Functional Characterization of the Multidomain F Plasmid TraI Relaxase-Helicase

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