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Mutagenic Consequences of Sublethal Cell Death Signaling

International journal of molecular sciences, 2021-06, Vol.22 (11), p.6144

2021

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CrmA orthologs from diverse poxviruses potently inhibit caspases-1 and -8, yet cleavage site mutagenesis frequently produces caspase-1-specific variants

Biochemical journal, 2019-05, Vol.476 (9), p.1335-1357

2019

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Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly

Cell reports (Cambridge), 2019-11, Vol.29 (7), p.1821-1831.e3

2019

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Low dose aspirin prevents endothelial dysfunction in the aorta and foetal loss in pregnant mice infected with influenza A virus

Frontiers in immunology, 2024-04, Vol.15, p.1378610-1378610

2024

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TLR7 promotes chronic airway disease in RSV-infected mice

Frontiers in immunology, 2023-09, Vol.14, p.1240552-1240552

2023

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Glycolysis and the Pentose Phosphate Pathway Promote LPS-Induced NOX2 Oxidase- and IFN-β-Dependent Inflammation in Macrophages

Antioxidants, 2022-07, Vol.11 (8), p.1488

2022

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TLR9 Monotherapy in Immune-Competent Mice Suppresses Orthotopic Prostate Tumor Development

Cells (Basel, Switzerland), 2024-01, Vol.13 (1), p.97

2024

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Therapeutic Targeting of Endosome and Mitochondrial Reactive Oxygen Species Protects Mice From Influenza Virus Morbidity

Frontiers in pharmacology, 2022-03, Vol.13, p.870156-870156

2022

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Influenza A virus infection during pregnancy causes immunological changes in gut-associated lymphoid tissues of offspring mice

American journal of physiology: Gastrointestinal and liver physiology, 2023-09, Vol.325 (3), p.G230-G238

2023

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Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine

Cell death & disease, 2017-10, Vol.8 (10), p.e3062-e3062

2017

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Mutagenic assessment of chemotherapy and Smac mimetic drugs in cells with defective DNA damage response pathways

Scientific reports, 2018-09, Vol.8 (1), p.14421-14, Article 14421

2018

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Gestational influenza A virus infection elicits nonresolving vascular dysfunction and T-cell accumulation in the aorta of mice

American journal of physiology. Heart and circulatory physiology, 2024-10, Vol.327 (4), p.H967-H977

2024

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The smac mimetic LCL161 targets established pulmonary osteosarcoma metastases in mice

Clinical & experimental metastasis, 2021-10, Vol.38 (5), p.441-449

2021

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In vitro analysis reveals necroptotic signaling does not provoke DNA damage or HPRT mutations

Cell death & disease, 2020-08, Vol.11 (8), p.680, Article 680

2020

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Brain region-specific alterations in gene expression trajectories in the offspring born from influenza A virus infected mice

Brain, behavior, and immunity, 2024-08, Vol.120, p.488-498

2024

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Proteasome inhibitors trigger mutations via activation of caspases and CAD, but mutagenesis provoked by the HDAC inhibitors vorinostat and romidepsin is caspase/CAD-independent

Apoptosis (London), 2019-06, Vol.24 (5-6), p.404-413

2019

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Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2

Nature structural & molecular biology, 2023-09, Vol.30 (9), p.1265-1274

2023

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Smac mimetics can provoke lytic cell death that is neither apoptotic nor necroptotic

Apoptosis (London), 2020-08, Vol.25 (7-8), p.500-518

2020

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Tetrazolium reduction assays under-report cell death provoked by clinically relevant concentrations of proteasome inhibitors

Molecular biology reports, 2020-06, Vol.47 (6), p.4849-4856

2020

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TRAIL causes deletions at the HPRT and TK1 loci of clonogenically competent cells

Mutation research, 2016-05, Vol.787, p.15-31

2016

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The Proteasome Inhibitor Ixazomib Inhibits the Formation and Growth of Pulmonary and Abdominal Osteosarcoma Metastases in Mice

Cancers, 2020-05, Vol.12 (5), p.1207

2020

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IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα

Oncotarget, 2016-06, Vol.7 (23), p.33866-33886

2016

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Transient NK Cell Depletion Facilitates Pulmonary Osteosarcoma Metastases After Intravenous Inoculation in Athymic Mice

Journal of adolescent and young adult oncology, 2020-12, Vol.9 (6), p.667-671

2020

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Cognitive Impairment in Children with Hemoglobin SS Sickle Cell Disease: Relationship to MR Imaging Findings and Hematocrit

American journal of neuroradiology : AJNR, 2003-03, Vol.24 (3), p.382-389

2003

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Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells

Mutation research, 2015-07, Vol.777, p.23-32

2015

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Mutagenic Consequences of Sublethal Cell Death Signaling

CrmA orthologs from diverse poxviruses potently inhibit caspases-1 and -8, yet cleavage site mutagenesis frequently produces caspase-1-specific variants

Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly

Low dose aspirin prevents endothelial dysfunction in the aorta and foetal loss in pregnant mice infected with influenza A virus

TLR7 promotes chronic airway disease in RSV-infected mice

Glycolysis and the Pentose Phosphate Pathway Promote LPS-Induced NOX2 Oxidase- and IFN-β-Dependent Inflammation in Macrophages

TLR9 Monotherapy in Immune-Competent Mice Suppresses Orthotopic Prostate Tumor Development

Therapeutic Targeting of Endosome and Mitochondrial Reactive Oxygen Species Protects Mice From Influenza Virus Morbidity

Influenza A virus infection during pregnancy causes immunological changes in gut-associated lymphoid tissues of offspring mice

Executioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine

Mutagenic assessment of chemotherapy and Smac mimetic drugs in cells with defective DNA damage response pathways

Gestational influenza A virus infection elicits nonresolving vascular dysfunction and T-cell accumulation in the aorta of mice

The smac mimetic LCL161 targets established pulmonary osteosarcoma metastases in mice

In vitro analysis reveals necroptotic signaling does not provoke DNA damage or HPRT mutations

Brain region-specific alterations in gene expression trajectories in the offspring born from influenza A virus infected mice

Proteasome inhibitors trigger mutations via activation of caspases and CAD, but mutagenesis provoked by the HDAC inhibitors vorinostat and romidepsin is caspase/CAD-independent

Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2

Smac mimetics can provoke lytic cell death that is neither apoptotic nor necroptotic

Tetrazolium reduction assays under-report cell death provoked by clinically relevant concentrations of proteasome inhibitors

TRAIL causes deletions at the HPRT and TK1 loci of clonogenically competent cells

The Proteasome Inhibitor Ixazomib Inhibits the Formation and Growth of Pulmonary and Abdominal Osteosarcoma Metastases in Mice

IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα

Transient NK Cell Depletion Facilitates Pulmonary Osteosarcoma Metastases After Intravenous Inoculation in Athymic Mice

Cognitive Impairment in Children with Hemoglobin SS Sickle Cell Disease: Relationship to MR Imaging Findings and Hematocrit

Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells

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