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Patched1 Regulates Hedgehog Signaling at the Primary Cilium

Science (American Association for the Advancement of Science), 2007-07, Vol.317 (5836), p.372-376

2007

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Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium

The Journal of cell biology, 2009-11, Vol.187 (3), p.365-374

2009

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The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

Genes & development, 2010-04, Vol.24 (7), p.670-682

2010

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Hedgehog signal transduction by Smoothened: Pharmacologic evidence for a 2-step activation process

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (9), p.3196-3201

2009

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Septin Diffusion Barrier at the Base of the Primary Cilium Maintains Ciliary Membrane Protein Distribution

Science (American Association for the Advancement of Science), 2010-07, Vol.329 (5990), p.436-439

2010

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Motional dynamics of single Patched1 molecules in cilia are controlled by Hedgehog and cholesterol

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (12), p.5550-5557

2019

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Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (27), p.8320-8325

2015

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A Genome-Wide Study of Gene Activity Reveals Developmental Signaling Pathways in the Preimplantation Mouse Embryo

Developmental cell, 2004, Vol.6 (1), p.133-144

2004

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A rapid and simple method for DNA engineering using cycled ligation assembly

PloS one, 2014-09, Vol.9 (9), p.e107329-e107329

2014

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Phosphodiesterase 4D acts downstream of Neuropilin to control Hedgehog signal transduction and the growth of medulloblastoma

eLife, 2015-09, Vol.4

2015

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Cell-autonomous death of cerebellar purkinje neurons with autophagy in Niemann-Pick type C disease

PLoS genetics, 2005-07, Vol.1 (1), p.81-95

2005

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Neuropilins are positive regulators of Hedgehog signal transduction

Genes & development, 2011-11, Vol.25 (22), p.2333-2346

2011

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Postmitotic centriole disengagement and maturation leads to centrosome amplification in polyploid trophoblast giant cells

Molecular biology of the cell, 2022-11, Vol.33 (13), p.ar118-ar118

2022

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Altered Neural Cell Fates and Medulloblastoma in Mouse patched Mutants

Science (American Association for the Advancement of Science), 1997-08, Vol.277 (5329), p.1109-1113

1997

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Quantifying Nanoscale Morphological Features of the Primary Cilium Membrane using Super-Resolution Fluorescence Microscopy

Biophysical journal, 2018-02, Vol.114 (3), p.268a-268a

2018

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Revealing Nanoscale Morphology of the Primary Cilium Using Super-Resolution Fluorescence Microscopy

Biophysical journal, 2019-01, Vol.116 (2), p.319-329

2019

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Several PATCHED1 Missense Mutations Display Activity in patched1-Deficient Fibroblasts

The Journal of biological chemistry, 2002-09, Vol.277 (37), p.33632-33640

2002

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Novel method for the scarless single‐step assembly of many small DNA sequences

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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Single-molecule imaging in the primary cilium

Methods in cell biology, 2023, Vol.176, p.59-83

2023

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Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Nature (London), 2000-08, Vol.406 (6799), p.1005-1009

2000

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Not lost in space: trafficking in the hedgehog signaling pathway

Science signaling, 2010-04, Vol.3 (117), p.pe14

2010

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Correction: Cell-Autonomous Death of Cerebellar Purkinje Neurons with Autophagy in Niemann-Pick Type C Disease

PLoS genetics, 2005-12, Vol.1 (6), p.e86

2005

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Single-Molecule Tracking of Smoothened in the Primary Cilium

Biophysical journal, 2014-01, Vol.106 (2), p.20a-20a

2014

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The Differences in the Cellular and Plasma Antioxidative Capacity Between Transient and Defined Focal Brain Ischemia: Does it Suggest Supporting Time-Dependent Neuroprotection Therapy?

Cellular and molecular neurobiology, 2016-07, Vol.36 (5), p.789-800

2016

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Mouse patched1 controls body size determination and limb patterning

Development (Cambridge), 1999-10, Vol.126 (20), p.4431-4440

1999

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Patched1 Regulates Hedgehog Signaling at the Primary Cilium

Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

Hedgehog signal transduction by Smoothened: Pharmacologic evidence for a 2-step activation process

Septin Diffusion Barrier at the Base of the Primary Cilium Maintains Ciliary Membrane Protein Distribution

Motional dynamics of single Patched1 molecules in cilia are controlled by Hedgehog and cholesterol

Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1

A Genome-Wide Study of Gene Activity Reveals Developmental Signaling Pathways in the Preimplantation Mouse Embryo

A rapid and simple method for DNA engineering using cycled ligation assembly

Phosphodiesterase 4D acts downstream of Neuropilin to control Hedgehog signal transduction and the growth of medulloblastoma

Cell-autonomous death of cerebellar purkinje neurons with autophagy in Niemann-Pick type C disease

Neuropilins are positive regulators of Hedgehog signal transduction

Postmitotic centriole disengagement and maturation leads to centrosome amplification in polyploid trophoblast giant cells

Altered Neural Cell Fates and Medulloblastoma in Mouse patched Mutants

Quantifying Nanoscale Morphological Features of the Primary Cilium Membrane using Super-Resolution Fluorescence Microscopy

Revealing Nanoscale Morphology of the Primary Cilium Using Super-Resolution Fluorescence Microscopy

Several PATCHED1 Missense Mutations Display Activity in patched1-Deficient Fibroblasts

Novel method for the scarless single‐step assembly of many small DNA sequences

Single-molecule imaging in the primary cilium

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Not lost in space: trafficking in the hedgehog signaling pathway

Correction: Cell-Autonomous Death of Cerebellar Purkinje Neurons with Autophagy in Niemann-Pick Type C Disease

Single-Molecule Tracking of Smoothened in the Primary Cilium

The Differences in the Cellular and Plasma Antioxidative Capacity Between Transient and Defined Focal Brain Ischemia: Does it Suggest Supporting Time-Dependent Neuroprotection Therapy?

Mouse patched1 controls body size determination and limb patterning

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