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HX‐1171, a Novel Nrf2 Activator, Induces NQO1 and HMOX1 Expression

Journal of cellular biochemistry, 2017-10, Vol.118 (10), p.3372-3380

2017

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Effects of 1-O-hexyl-2,3,5-trimethylhydroquinone on carbon tetrachloride-induced hepatic cirrhosis in rats

Hepatology research, 2010-06, Vol.40 (6), p.613-621

2010

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Single and multiple dose pharmacokinetics and tolerability of HX-1171, a novel antioxidant, in healthy volunteers

Drug design, development and therapy, 2015-01, Vol.9, p.1735-1742

2015

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Chemoprevention of acrylamide toxicity by antioxidative agents in rats : effective suppression of testicular toxicity by phenylethyl isothiocyanate

Archives of toxicology, 2005-09, Vol.79 (9), p.531-541

2005

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Chemoprevention of 2-amino-1-methyl-6-phenylimidazo- [4,5-b]pyridine-induced colon carcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone after initiation with 1,2-dimethylhydrazine in F344 rats

Carcinogenesis (New York), 2002-02, Vol.23 (2), p.283-287

2002

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Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6-methyldipyrido[l,2-a: 3′ ,2′ -d]imidazole (Glu-P-1)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)

Carcinogenesis (New York), 1995-12, Vol.16 (12), p.3049-3055

1995

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Effects of Antioxidant 1‐O‐Hexyl‐2,3,5‐trimethylhydroquinone or Ascorbic Acid on Carcinogenesis Induced by Administration of Aminopyrine and Sodium Nitrite in a Rat Multi‐organ Carcinogenesis Model

Cancer science, 2002-12, Vol.93 (12), p.1299-1307

2002

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Stage and organ dependent effects of 1‐ O‐hexyl‐2,3,5‐trimethylhydroquinone, ascorbic acid derivatives, N‐heptadecane‐8,10‐dione and phenylethyl isothiocyanate in a rat multiorgan carcinogenesis model

International journal of cancer, 1998-06, Vol.76 (6), p.851-856

1998

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3,4-Dihydroxychalcones as potent 5-lipoxygenase and cyclooxygenase inhibitors

Journal of medicinal chemistry, 1993-11, Vol.36 (24), p.3904-3909

1993

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Dose Dependence of 1‐O‐Hexyl‐2,3,5‐trimethylhydroquinone Promotion of Forestomach Carcinogenesis in Rats Pretreated with N‐Ethylnitrosourethane

Cancer science, 1998-05, Vol.89 (5), p.475-480

1998

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Protective Effects of Hydroxychalcones on Free Radical-Induced Cell Damage

Biological and Pharmaceutical Bulletin, 1994/02/15, Vol.17(2), pp.251-256

1994

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Strong anti-mutagenic activity of the novel lipophilic antioxidant 1-O-hexyl-2,3,5-trimethylhydroquinone against heterocyclic amine-induced mutagenesis in the Ames assay and its effect on metabolic activation of 2-Amino-6-methyldipyrido[1,2-a:3′, 2′-d]imidazole (Glu-P-1)

Carcinogenesis (New York), 1995-09, Vol.16 (9), p.2227-2232

1995

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Effects of 1-O-hexyl-2, 3, 5-trimethylhydroquinone in Carbon Tetrachloride-induced Hepatic Apoptosis with a Possible Relationship to Naofen

International journal of pharmacology, 2012-07, Vol.8 (5), p.434-439

2012

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Gastric cytoprotective anti-ulcerogenic actions of hydroxychalcones in rats

Planta medica, 1992-10, Vol.58 (5), p.389-393

1992

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Synthesis and Anti Lipid-Peroxidation Activity of Hydroquinone Monoalkyl Ethers

Chemical and Pharmaceutical Bulletin, 1994/03/15, Vol.42(3), pp.576-579

1994

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Strong Inhibition of 2‐Amino‐6‐methyldipyrido[l,2‐a:3′,2′‐d]imidazole‐induced Mutagenesis and Hepatocarcinogenesis by 1‐O‐Hexyl‐2,3,5‐trimethylhydroquinone

Cancer science, 1993-05, Vol.84 (5), p.481-484

1993

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1-0-Hexyl-2,3,5-trimethylhydroquinone inhibits IκB phosphorylation and degradation-linked inducible nitric oxide synthase expression: beyond antioxidant function

Journal of pharmacy and pharmacology, 2002-03, Vol.54 (3), p.383-389

2002

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1-O-hexyl-2,3,5-trimethylhydroquinone inhibits IkappaB phosphorylation and degradation-linked inducible nitric oxide synthase expression: beyond antioxidant function

Journal of pharmacy and pharmacology, 2002-03, Vol.54 (3), p.383-389

2002

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3-O-alkylascorbic acids as free radical quenchers. II: Inhibitory effects of some lipid peroxidation models

Chemical & pharmaceutical bulletin, 1991-01, Vol.39 (7), p.1731-1735

1991

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1-O-Hexyl-2,3,5-trimethylhydroquinone inhibits IκB phosphorylation and degradation-linked inducible nitric oxide synthase expression: beyond antioxidant function

Journal of pharmacy and pharmacology, 2002-03, Vol.54 (3), p.383-389

2002

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3-O-alkylascorbic acids as free radical quenchers. 3. Protective effect on coronary occlusion-reperfusion induced arrhythmias in anesthetized rats

Journal of medicinal chemistry, 1992-05, Vol.35 (9), p.1618-1623

1992

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SIGNIFICANCE OF PRIMARY SPONGIOSA IN TIBIA TEST OF GROWTH HORMONE

Endocrinologia Japonica, 1962, Vol.9(3), pp.205-222

1962

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P-54 Effects of 1-O-hexyl-2, 3, 5-trimethylhydroquinone on IκB phosphorylation and degradation-linked inducible nitric oxide synthase expression:beyond antioxidant function

Japanese Journal of Pharmacology, 2002, Vol.88 (suppl.2), p.75-75

2002

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3-O-Alkuylascorbic Acids as Free Radical Quenchers. II. Inhibitory Effects on Some Lipid Peroxidation Models

Chemical and Pharmaceutical Bulletin, 1991/07/25, Vol.39(7), pp.1731-1735

1991

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A novel sphingosine 1-phosphate receptor agonist, 2-amino-2-propanediol hydrochloride (KRP-203), regulates chronic colitis in interleukin-10 gene-deficient mice

The Journal of pharmacology and experimental therapeutics, 2008-01, Vol.324 (1), p.276-283

2008

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HX‐1171, a Novel Nrf2 Activator, Induces NQO1 and HMOX1 Expression

Effects of 1-O-hexyl-2,3,5-trimethylhydroquinone on carbon tetrachloride-induced hepatic cirrhosis in rats

Single and multiple dose pharmacokinetics and tolerability of HX-1171, a novel antioxidant, in healthy volunteers

Chemoprevention of acrylamide toxicity by antioxidative agents in rats : effective suppression of testicular toxicity by phenylethyl isothiocyanate

Chemoprevention of 2-amino-1-methyl-6-phenylimidazo- [4,5-b]pyridine-induced colon carcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone after initiation with 1,2-dimethylhydrazine in F344 rats

Effects of Antioxidant 1‐O‐Hexyl‐2,3,5‐trimethylhydroquinone or Ascorbic Acid on Carcinogenesis Induced by Administration of Aminopyrine and Sodium Nitrite in a Rat Multi‐organ Carcinogenesis Model

Stage and organ dependent effects of 1‐ O‐hexyl‐2,3,5‐trimethylhydroquinone, ascorbic acid derivatives, N‐heptadecane‐8,10‐dione and phenylethyl isothiocyanate in a rat multiorgan carcinogenesis model

3,4-Dihydroxychalcones as potent 5-lipoxygenase and cyclooxygenase inhibitors

Dose Dependence of 1‐O‐Hexyl‐2,3,5‐trimethylhydroquinone Promotion of Forestomach Carcinogenesis in Rats Pretreated with N‐Ethylnitrosourethane

Protective Effects of Hydroxychalcones on Free Radical-Induced Cell Damage

Strong anti-mutagenic activity of the novel lipophilic antioxidant 1-O-hexyl-2,3,5-trimethylhydroquinone against heterocyclic amine-induced mutagenesis in the Ames assay and its effect on metabolic activation of 2-Amino-6-methyldipyrido[1,2-a:3′, 2′-d]imidazole (Glu-P-1)

Effects of 1-O-hexyl-2, 3, 5-trimethylhydroquinone in Carbon Tetrachloride-induced Hepatic Apoptosis with a Possible Relationship to Naofen

Gastric cytoprotective anti-ulcerogenic actions of hydroxychalcones in rats

Synthesis and Anti Lipid-Peroxidation Activity of Hydroquinone Monoalkyl Ethers

Strong Inhibition of 2‐Amino‐6‐methyldipyrido[l,2‐a:3′,2′‐d]imidazole‐induced Mutagenesis and Hepatocarcinogenesis by 1‐O‐Hexyl‐2,3,5‐trimethylhydroquinone

1-0-Hexyl-2,3,5-trimethylhydroquinone inhibits IκB phosphorylation and degradation-linked inducible nitric oxide synthase expression: beyond antioxidant function

1-O-hexyl-2,3,5-trimethylhydroquinone inhibits IkappaB phosphorylation and degradation-linked inducible nitric oxide synthase expression: beyond antioxidant function

3-O-alkylascorbic acids as free radical quenchers. II: Inhibitory effects of some lipid peroxidation models

1-O-Hexyl-2,3,5-trimethylhydroquinone inhibits IκB phosphorylation and degradation-linked inducible nitric oxide synthase expression: beyond antioxidant function

3-O-alkylascorbic acids as free radical quenchers. 3. Protective effect on coronary occlusion-reperfusion induced arrhythmias in anesthetized rats

SIGNIFICANCE OF PRIMARY SPONGIOSA IN TIBIA TEST OF GROWTH HORMONE

P-54 Effects of 1-O-hexyl-2, 3, 5-trimethylhydroquinone on IκB phosphorylation and degradation-linked inducible nitric oxide synthase expression:beyond antioxidant function

3-O-Alkuylascorbic Acids as Free Radical Quenchers. II. Inhibitory Effects on Some Lipid Peroxidation Models

A novel sphingosine 1-phosphate receptor agonist, 2-amino-2-propanediol hydrochloride (KRP-203), regulates chronic colitis in interleukin-10 gene-deficient mice

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