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Plasma metabolites to profile pathways in noncommunicable disease multimorbidity

Nature medicine, 2021-03, Vol.27 (3), p.471-479

2021

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Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis

American journal of physiology: Gastrointestinal and liver physiology, 2015-02, Vol.308 (4), p.G298-G312

2015

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Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer

PloS one, 2011-09, Vol.6 (9), p.e23943

2011

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Cross‐talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice

Hepatology (Baltimore, Md.), 2013-11, Vol.58 (5), p.1801-1813

2013

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TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice

PloS one, 2014-01, Vol.9 (1), p.e83987

2014

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Leptin Promotes the Myofibroblastic Phenotype in Hepatic Stellate Cells by Activating the Hedgehog Pathway

The Journal of biological chemistry, 2010-11, Vol.285 (47), p.36551-36560

2010

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Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis

Hepatology (Baltimore, Md.), 2011-01, Vol.53 (1), p.106-115

2011

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Vitamin A carotenoids, but not retinoids, mediate the impact of a healthy diet on gut microbial diversity

BMC medicine, 2024-08, Vol.22 (1), p.1-11, Article 321

2024

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Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis

American journal of physiology: Gastrointestinal and liver physiology, 2009-12, Vol.297 (6), p.G1093-G1106

2009

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NAFLD, NASH and liver cancer

Nature reviews. Gastroenterology & hepatology, 2013-11, Vol.10 (11), p.656

2013

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Upregulation of miR21 and repression of Grhl3 by leptin mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis

PloS one, 2015-02, Vol.10 (2), p.e0116780

2015

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Machine Learning Metabolomics Profiling of Dietary Interventions from a Six-Week Randomised Trial

Metabolites, 2024-06, Vol.14 (6), p.311

2024

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Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells

Gastroenterology (New York, N.Y. 1943), 2018-04, Vol.154 (5), p.1465-1479.e13

2018

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Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population

Metabolites, 2019-04, Vol.9 (4), p.61

2019

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Temporal Dissection of Rate Limiting Transcriptional Events Using Pol II ChIP and RNA Analysis of Adrenergic Stress Gene Activation

PloS one, 2015-08, Vol.10 (8), p.e0134442-e0134442

2015

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Smoothened is a master regulator of adult liver repair

The Journal of clinical investigation, 2013-06, Vol.123 (6), p.2380-2394

2013

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The Roles of Gut Microbiome and Plasma Metabolites in the Associations between ABO Blood Groups and Insulin Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES)

Metabolites, 2022-08, Vol.12 (9), p.787

2022

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Hedgehog regulates yes‐associated protein 1 in regenerating mouse liver

Hepatology (Baltimore, Md.), 2016-07, Vol.64 (1), p.232-244

2016

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Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease

Hepatology (Baltimore, Md.), 2014-02, Vol.59 (2), p.471-482

2014

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Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism

Gastroenterology (New York, N.Y. 1943), 2012-11, Vol.143 (5), p.1319-1329.e11

2012

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Evidence That Phosphorylation of the RNA Polymerase II Carboxyl-terminal Repeats Is Similar in Yeast and Humans

The Journal of biological chemistry, 2005-09, Vol.280 (36), p.31368-31377

2005

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Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets

Journal of proteome research, 2017-06, Vol.16 (6), p.2294-2306

2017

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NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease

Gut, 2012-09, Vol.61 (9), p.1323-1329

2012

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Plasma metabolites to profile pathways in noncommunicable disease multimorbidity

Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis

Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer

Cross‐talk between Notch and Hedgehog regulates hepatic stellate cell fate in mice

TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice

Leptin Promotes the Myofibroblastic Phenotype in Hepatic Stellate Cells by Activating the Hedgehog Pathway

Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis

Vitamin A carotenoids, but not retinoids, mediate the impact of a healthy diet on gut microbial diversity

Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis

NAFLD, NASH and liver cancer

Upregulation of miR21 and repression of Grhl3 by leptin mediates sinusoidal endothelial injury in experimental nonalcoholic steatohepatitis

Machine Learning Metabolomics Profiling of Dietary Interventions from a Six-Week Randomised Trial

Genetic and gut microbiome determinants of SCFA circulating and fecal levels, postprandial responses and links to chronic and acute inflammation

Hedgehog-YAP Signaling Pathway Regulates Glutaminolysis to Control Activation of Hepatic Stellate Cells

Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population

Temporal Dissection of Rate Limiting Transcriptional Events Using Pol II ChIP and RNA Analysis of Adrenergic Stress Gene Activation

Smoothened is a master regulator of adult liver repair

The Roles of Gut Microbiome and Plasma Metabolites in the Associations between ABO Blood Groups and Insulin Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES)

Hedgehog regulates yes‐associated protein 1 in regenerating mouse liver

Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease

Hedgehog Controls Hepatic Stellate Cell Fate by Regulating Metabolism

Evidence That Phosphorylation of the RNA Polymerase II Carboxyl-terminal Repeats Is Similar in Yeast and Humans

Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets

Rare and common genetic determinants of metabolic individuality and their effects on human health

NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease

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