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An Antiproliferative Factor from Interstitial Cystitis Patients Is a Frizzled 8 Protein-Related Sialoglycopeptide

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (32), p.11803-11808

2004

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CKAP4/p63 Is a Receptor for the Frizzled-8 Protein-related Antiproliferative Factor from Interstitial Cystitis Patients

The Journal of biological chemistry, 2006-12, Vol.281 (49), p.37836-37843

2006

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Synthesis and Biological Activity of Novel Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase. 2-Aryl-Substituted Benzimidazoles

Journal of medicinal chemistry, 1997-12, Vol.40 (26), p.4199-4207

1997

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Optimization of Naphthalimide-imidazoacridone with Potent Antitumor Activity Leading to Clinical Candidate (HKH40A, RTA 502)

Journal of medicinal chemistry, 2007-11, Vol.50 (23), p.5557-5560

2007

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A New Synthetic Agent with Potent but Selective Cytotoxic Activity against Cancer

Journal of medicinal chemistry, 2005-06, Vol.48 (13), p.4474-4481

2005

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PM-20, a novel inhibitor of Cdc25A, induces extracellular signal–regulated kinase 1/2 phosphorylation and inhibits hepatocellular carcinoma growth in vitro and in vivo

Molecular cancer therapeutics, 2006-06, Vol.5 (6), p.1511-1519

2006

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Synthesis and biological activity of 5-aza-ellipticine derivatives

Bioorganic & medicinal chemistry letters, 2007-04, Vol.17 (8), p.2380-2384

2007

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Synthesis, Biological Activity, and Crystal Structure of Potent Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase That Retain Activity against Mutant Forms of the Enzyme

Journal of medicinal chemistry, 2007-08, Vol.50 (17), p.4003-4015

2007

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WMC-79, a potent agent against colon cancers, induces apoptosis through a p53-dependent pathway

Molecular cancer therapeutics, 2005-10, Vol.4 (10), p.1617-1627

2005

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Caspase-mediated apoptosis and caspase-independent cell death induced by irofulven in prostate cancer cells

Molecular cancer therapeutics, 2004-11, Vol.3 (11), p.1385-1396

2004

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Rationally Designed Inhibitors Identify STAT3 N-Domain as a Promising Anticancer Drug Target

ACS chemical biology, 2007-12, Vol.2 (12), p.799-809

2007

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Design and Synthesis of Novel and Potent Inhibitors of the Type II Transmembrane Serine Protease, Matriptase, Based upon the Sunflower Trypsin Inhibitor-1

Journal of medicinal chemistry, 2007-11, Vol.50 (24), p.5976-5983

2007

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Small molecule toxins targeting tumor receptors

Current pharmaceutical design, 2004-07, Vol.10 (19), p.2311-2334

2004

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Spontaneous and Ligand-induced Trafficking of CXC-Chemokine Receptor 4

The Journal of biological chemistry, 1998-06, Vol.273 (26), p.15883-15886

1998

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Inhibition of Acute-, Latent-, and Chronic-Phase Human Immunodeficiency Virus Type 1 (HIV-1) Replication by a Bistriazoloacridone Analog That Selectively Inhibits HIV-1 Transcription

Antimicrobial Agents and Chemotherapy, 1998-03, Vol.42 (3), p.487-494

1998

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Transmembrane Inhibitors of P-Glycoprotein, an ABC Transporter

Journal of medicinal chemistry, 2005-06, Vol.48 (11), p.3768-3775

2005

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Cytotoxic Agents Directed to Peptide Hormone Receptors: Defining the Requirements for a Successful Drug

Proceedings of the National Academy of Sciences - PNAS, 1998-09, Vol.95 (20), p.11520-11525

1998

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Structure−Activity Relationship Studies for the Peptide Portion of the Bladder Epithelial Cell Antiproliferative Factor from Interstitial Cystitis Patients

Journal of medicinal chemistry, 2008-10, Vol.51 (19), p.5974-5983

2008

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Inhibition of G-protein-coupled Receptor Function by Disruption of Transmembrane Domain Interactions

The Journal of biological chemistry, 1999-12, Vol.274 (49), p.34911-34915

1999

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Bombesin marine toxin conjugates inhibit the growth of lung cancer cells

Life sciences (1973), 2008-04, Vol.82 (15), p.855-861

2008

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Development of antiproliferative phenylmaleimides that activate the unfolded protein response

Bioorganic & medicinal chemistry, 2010-06, Vol.18 (12), p.4535-4541

2010

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Structure of HIV-1 nonnucleoside reverse transcriptase inhibitors derivatives of N-benzyl-benzimidazole with different substituents in position 4

Journal of molecular structure, 2010-01, Vol.963 (2), p.188-193

2010

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Growth inhibition of hepatocellular carcinoma cells in vitro and in vivo by the 8-methoxy analog of WMC79

Cancer chemotherapy and pharmacology, 2009-04, Vol.63 (5), p.769-778

2009

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Crystal structures of HIV-1 nonnucleoside reverse transcriptase inhibitors: N-benzyl-4-methyl-benzimidazoles

Journal of molecular structure, 2009-07, Vol.930 (1), p.157-161

2009

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Structural studies of series HIV-1 nonnucleoside reverse transcriptase inhibitors 1-(2,6-difluorobenzyl)-2-(2,6-difluorophenyl)-benzimidazoles with different 4-substituents

Journal of molecular structure, 2010-03, Vol.966 (1), p.53-58

2010

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An Antiproliferative Factor from Interstitial Cystitis Patients Is a Frizzled 8 Protein-Related Sialoglycopeptide

CKAP4/p63 Is a Receptor for the Frizzled-8 Protein-related Antiproliferative Factor from Interstitial Cystitis Patients

Synthesis and Biological Activity of Novel Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase. 2-Aryl-Substituted Benzimidazoles

Optimization of Naphthalimide-imidazoacridone with Potent Antitumor Activity Leading to Clinical Candidate (HKH40A, RTA 502)

A New Synthetic Agent with Potent but Selective Cytotoxic Activity against Cancer

PM-20, a novel inhibitor of Cdc25A, induces extracellular signal–regulated kinase 1/2 phosphorylation and inhibits hepatocellular carcinoma growth in vitro and in vivo

Synthesis and biological activity of 5-aza-ellipticine derivatives

Synthesis, Biological Activity, and Crystal Structure of Potent Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase That Retain Activity against Mutant Forms of the Enzyme

WMC-79, a potent agent against colon cancers, induces apoptosis through a p53-dependent pathway

Caspase-mediated apoptosis and caspase-independent cell death induced by irofulven in prostate cancer cells

Rationally Designed Inhibitors Identify STAT3 N-Domain as a Promising Anticancer Drug Target

Design and Synthesis of Novel and Potent Inhibitors of the Type II Transmembrane Serine Protease, Matriptase, Based upon the Sunflower Trypsin Inhibitor-1

Small molecule toxins targeting tumor receptors

Spontaneous and Ligand-induced Trafficking of CXC-Chemokine Receptor 4

Inhibition of Acute-, Latent-, and Chronic-Phase Human Immunodeficiency Virus Type 1 (HIV-1) Replication by a Bistriazoloacridone Analog That Selectively Inhibits HIV-1 Transcription

Transmembrane Inhibitors of P-Glycoprotein, an ABC Transporter

Cytotoxic Agents Directed to Peptide Hormone Receptors: Defining the Requirements for a Successful Drug

Structure−Activity Relationship Studies for the Peptide Portion of the Bladder Epithelial Cell Antiproliferative Factor from Interstitial Cystitis Patients

Inhibition of G-protein-coupled Receptor Function by Disruption of Transmembrane Domain Interactions

Bombesin marine toxin conjugates inhibit the growth of lung cancer cells

Development of antiproliferative phenylmaleimides that activate the unfolded protein response

Structure of HIV-1 nonnucleoside reverse transcriptase inhibitors derivatives of N-benzyl-benzimidazole with different substituents in position 4

Growth inhibition of hepatocellular carcinoma cells in vitro and in vivo by the 8-methoxy analog of WMC79

Crystal structures of HIV-1 nonnucleoside reverse transcriptase inhibitors: N-benzyl-4-methyl-benzimidazoles

Structural studies of series HIV-1 nonnucleoside reverse transcriptase inhibitors 1-(2,6-difluorobenzyl)-2-(2,6-difluorophenyl)-benzimidazoles with different 4-substituents

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