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Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies

Cell reports (Cambridge), 2019-05, Vol.27 (8), p.2411-2425.e9

2019

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Identification of a regulatory Vδ1 gamma delta T cell subpopulation expressing CD73 in human breast cancer

Journal of leukocyte biology, 2020-06, Vol.107 (6), p.1057-1067

2020

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Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related ( ATR ) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer

Cancer research (Chicago, Ill.), 2019-06, Vol.79 (11), p.2933-2946

2019

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A 31-plex panel for high-dimensional single-cell analysis of murine preclinical models of solid tumors by imaging mass cytometry

Frontiers in immunology, 2023-01, Vol.13, p.1011617-1011617

2023

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The IL-17B-IL-17 receptor B pathway promotes resistance to paclitaxel in breast tumors through activation of the ERK1/2 pathway

Oncotarget, 2017-12, Vol.8 (69), p.113360-113372

2017

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IL-21 promotes the development of a CD73-positive Vγ9Vδ2 T cell regulatory population

Oncoimmunology, 2018-01, Vol.7 (1), p.e1379642-e1379642

2018

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An NF-κB–Dependent Role for JunB in the Induction of Proinflammatory Cytokines in LPS-Activated Bone Marrow–Derived Dendritic Cells

PloS one, 2010-03, Vol.5 (3), p.e9585

2010

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A crucial role for infected-cell/antibody immune complexes in the enhancement of endogenous antiviral immunity by short passive immunotherapy

PLoS pathogens, 2010-06, Vol.6 (6), p.e1000948-e1000948

2010

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Long-Lasting Protective Antiviral Immunity Induced by Passive Immunotherapies Requires both Neutralizing and Effector Functions of the Administered Monoclonal Antibody

Journal of Virology, 2010-10, Vol.84 (19), p.10169-10181

2010

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First-line durvalumab and tremelimumab with chemotherapy in RAS-mutated metastatic colorectal cancer: a phase 1b/2 trial

Nature medicine, 2023-08, Vol.29 (8), p.2087-2098

2023

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PD-1 blockade at the time of tumor escape potentiates the immune-mediated antitumor effects of a melanoma-targeting monoclonal antibody

Oncoimmunology, 2017-01, Vol.6 (10), p.e1353857-e1353857

2017

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Functional specialization of short-lived and long-lived macrophage subsets in human tonsils

The Journal of experimental medicine, 2023-07, Vol.220 (7)

2023

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Plasticity of γδ T Cells: Impact on the Anti-Tumor Response

Frontiers in immunology, 2014, Vol.5, p.622-622

2014

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Single-cell high-dimensional imaging mass cytometry: one step beyond in oncology

Seminars in immunopathology, 2023-01, Vol.45 (1), p.17-28

2023

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Comprehensive analysis of cell lineages involved in giant cell arteritis pathogenesis using highly multiplexed imaging mass cytometry

Autoimmunity reviews, 2023-01, Vol.22 (1), p.103216, Article 103216

2023

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Higher Anti-Tumor Efficacy of the Dual HER3-EGFR Antibody MEHD7945a Combined with Ionizing Irradiation in Cervical Cancer Cells

International journal of radiation oncology, biology, physics, 2020-04, Vol.106 (5), p.1039-1051

2020

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Endogenous Cytotoxic T-Cell Response Contributes to the Long-Term Antiretroviral Protection Induced by a Short Period of Antibody-Based Immunotherapy of Neonatally Infected Mice

Journal of Virology, 2008-02, Vol.82 (3), p.1339-1349

2008

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CD73: a new biomarker in triple-negative breast cancer

Translational cancer research, 2018-06, Vol.7 (S5), p.S594-S596

2018

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Cutting edge: An antibody recognizing ancestral endogenous virus glycoproteins mediates antibody-dependent cellular cytotoxicity on HIV-1-infected cells

The Journal of immunology (1950), 2014-08, Vol.193 (4), p.1544-1548

2014

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Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers

Retrovirology, 2017-08, Vol.14 (1), p.41-41, Article 41

2017

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Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection

Retrovirology, 2014-01, Vol.11 (1), p.10-10, Article 10

2014

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Diminished humoral responses against and reduced gene expression levels of human endogenous retrovirus-K (HERV-K) in psoriasis

Journal of translational medicine, 2014-09, Vol.12 (1), p.256-256, Article 256

2014

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Protective Effect of Human Endogenous Retrovirus K dUTPase Variants on Psoriasis Susceptibility

Journal of investigative dermatology, 2012-07, Vol.132 (7), p.1833-1840

2012

Volltextzugriff (PDF)

An NF-kappaB-dependent role for JunB in the induction of proinflammatory cytokines in LPS-activated bone marrow-derived dendritic cells

PloS one, 2010-03, Vol.5 (3), p.e9585-e9585

2010

Volltextzugriff (PDF)

Plasticity of gamma delta T cells: impact on the anti-tumor response

Frontiers in immunology, 2014-12, Vol.5

2014

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Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies

Identification of a regulatory Vδ1 gamma delta T cell subpopulation expressing CD73 in human breast cancer

Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related ( ATR ) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer

A 31-plex panel for high-dimensional single-cell analysis of murine preclinical models of solid tumors by imaging mass cytometry

The IL-17B-IL-17 receptor B pathway promotes resistance to paclitaxel in breast tumors through activation of the ERK1/2 pathway

IL-21 promotes the development of a CD73-positive Vγ9Vδ2 T cell regulatory population

An NF-κB–Dependent Role for JunB in the Induction of Proinflammatory Cytokines in LPS-Activated Bone Marrow–Derived Dendritic Cells

A crucial role for infected-cell/antibody immune complexes in the enhancement of endogenous antiviral immunity by short passive immunotherapy

Long-Lasting Protective Antiviral Immunity Induced by Passive Immunotherapies Requires both Neutralizing and Effector Functions of the Administered Monoclonal Antibody

First-line durvalumab and tremelimumab with chemotherapy in RAS-mutated metastatic colorectal cancer: a phase 1b/2 trial

PD-1 blockade at the time of tumor escape potentiates the immune-mediated antitumor effects of a melanoma-targeting monoclonal antibody

Functional specialization of short-lived and long-lived macrophage subsets in human tonsils

Plasticity of γδ T Cells: Impact on the Anti-Tumor Response

Single-cell high-dimensional imaging mass cytometry: one step beyond in oncology

Comprehensive analysis of cell lineages involved in giant cell arteritis pathogenesis using highly multiplexed imaging mass cytometry

Higher Anti-Tumor Efficacy of the Dual HER3-EGFR Antibody MEHD7945a Combined with Ionizing Irradiation in Cervical Cancer Cells

Endogenous Cytotoxic T-Cell Response Contributes to the Long-Term Antiretroviral Protection Induced by a Short Period of Antibody-Based Immunotherapy of Neonatally Infected Mice

CD73: a new biomarker in triple-negative breast cancer

Cutting edge: An antibody recognizing ancestral endogenous virus glycoproteins mediates antibody-dependent cellular cytotoxicity on HIV-1-infected cells

Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers

Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection

Diminished humoral responses against and reduced gene expression levels of human endogenous retrovirus-K (HERV-K) in psoriasis

Protective Effect of Human Endogenous Retrovirus K dUTPase Variants on Psoriasis Susceptibility

An NF-kappaB-dependent role for JunB in the induction of proinflammatory cytokines in LPS-activated bone marrow-derived dendritic cells

Plasticity of gamma delta T cells: impact on the anti-tumor response

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