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APOE ε4: The most prevalent yet understudied risk factor for Alzheimer's disease

Alzheimer's & dementia, 2014-11, Vol.10 (6), p.861-868

Michaelson, Daniel M

2014

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ApoE4: an emerging therapeutic target for Alzheimer's disease

BMC medicine, 2019-03, Vol.17 (1), p.64-17, Article 64

2019

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ApoE4 Alters ABCA1 Membrane Trafficking in Astrocytes

The Journal of neuroscience, 2019-11, Vol.39 (48), p.9611-9622

2019

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Omega-3 fatty acids, lipids, and apoE lipidation in Alzheimer's disease: a rationale for multi-nutrient dementia prevention

Journal of lipid research, 2017-11, Vol.58 (11), p.2083-2101

2017

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An Anti-apoE4 Specific Monoclonal Antibody Counteracts the Pathological Effects of apoE4 In Vivo

Current Alzheimer research, 2016-08, Vol.13 (8), p.918

2016

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The Effects of APOE4 on Mitochondrial Dynamics and Proteins in vivo

Journal of Alzheimer's disease, 2019-01, Vol.70 (3), p.861

2019

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ABCA1 Agonist Reverses the ApoE4-Driven Cognitive and Brain Pathologies

Journal of Alzheimer's disease, 2016-10, Vol.54 (3), p.1219

2016

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APOE epsilon 4: The most prevalent yet understudied risk factor for Alzheimer's disease

Alzheimer's & dementia, 2014-11, Vol.10 (6), p.861-868

Michaelson, Daniel M

2014

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Central and Peripheral Mechanisms in ApoE4-Driven Diabetic Pathology

International journal of molecular sciences, 2020-02, Vol.21 (4), p.1289

2020

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Differential Effects of apoE4 and Activation of ABCA1 on Brain and Plasma Lipoproteins

PloS one, 2016-11, Vol.11 (11), p.e0166195-e0166195

2016

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Reversal of apoE4-driven brain pathology and behavioral deficits by bexarotene

The Journal of neuroscience, 2014-05, Vol.34 (21), p.7293-7301

2014

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Activation of the Amyloid Cascade in Apolipoprotein E4 Transgenic Mice Induces Lysosomal Activation and Neurodegeneration Resulting in Marked Cognitive Deficits

The Journal of neuroscience, 2008-04, Vol.28 (18), p.4690-4701

2008

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ApoE4 induces synaptic and ERG impairments in the retina of young targeted replacement apoE4 mice

PloS one, 2013-05, Vol.8 (5), p.e64949-e64949

2013

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A Nontransgenic Mouse Model Shows Inducible Amyloid-β (Aβ) Peptide Deposition and Elucidates the Role of Apolipoprotein E in the Amyloid Cascade

Proceedings of the National Academy of Sciences - PNAS, 2004-09, Vol.101 (38), p.13909-13914

2004

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Involvement of the Apoer2 and Lrp1 receptors in mediating the pathological effects of ApoE4 in vivo

Current Alzheimer research, 2014-01, Vol.11 (6), p.549

2014

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Hippocampus-Related Cognitive Impairments in Young apoE4 Targeted Replacement Mice

Neuro-degenerative diseases, 2014-01, Vol.13 (2-3), p.86-92

2014

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The effects of apolipoprotein E genotype, α-synuclein deficiency, and sex on brain synaptic and Alzheimer's disease–related pathology

Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2018, Vol.10 (1), p.1-11

2018

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VEGF Mediates ApoE4-Induced Neovascularization and Synaptic Pathology in the Choroid and Retina

Current Alzheimer research, 2015-01, Vol.12 (4), p.323

2015

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ApoE ε4 is associated with eIF2α phosphorylation and impaired learning in young mice

Neurobiology of aging, 2013-03, Vol.34 (3), p.863-872

2013

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ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice

Molecular neurodegeneration, 2013-05, Vol.8 (1), p.16-16, Article 16

2013

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ApoE4 impairs hippocampal plasticity isoform-specifically and blocks the environmental stimulation of synaptogenesis and memory

Neurobiology of disease, 2003-08, Vol.13 (3), p.273-282

2003

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9-cis beta-carotene-enriched diet significantly improved cognition and decreased Alzheimer’s disease neuropathology and neuroinflammation in Alzheimer’s disease-like mouse models

Neurobiology of aging, 2024-01, Vol.133, p.16-27

2024

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Behavioral testing affects the phenotypic expression of APOE ε3 and APOE ε4 in targeted replacement mice and reduces the differences between them

Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2015-06, Vol.1 (2), p.127-135

2015

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Anatomical localization of protease‐activated receptor‐1 and protease‐mediated neuroglilal crosstalk on peri‐synaptic astrocytic endfeet

Journal of neurochemistry, 2011-11, Vol.119 (3), p.460-473

2011

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Environmental enrichment stimulates neurogenesis in apolipoprotein E3 and neuronal apoptosis in apolipoprotein E4 transgenic mice

Journal of neurochemistry, 2007, Vol.100 (1), p.202-210

2007

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APOE ε4: The most prevalent yet understudied risk factor for Alzheimer's disease

ApoE4: an emerging therapeutic target for Alzheimer's disease

ApoE4 Alters ABCA1 Membrane Trafficking in Astrocytes

Omega-3 fatty acids, lipids, and apoE lipidation in Alzheimer's disease: a rationale for multi-nutrient dementia prevention

An Anti-apoE4 Specific Monoclonal Antibody Counteracts the Pathological Effects of apoE4 In Vivo

The Effects of APOE4 on Mitochondrial Dynamics and Proteins in vivo

ABCA1 Agonist Reverses the ApoE4-Driven Cognitive and Brain Pathologies

APOE epsilon 4: The most prevalent yet understudied risk factor for Alzheimer's disease

Central and Peripheral Mechanisms in ApoE4-Driven Diabetic Pathology

Differential Effects of apoE4 and Activation of ABCA1 on Brain and Plasma Lipoproteins

Reversal of apoE4-driven brain pathology and behavioral deficits by bexarotene

Activation of the Amyloid Cascade in Apolipoprotein E4 Transgenic Mice Induces Lysosomal Activation and Neurodegeneration Resulting in Marked Cognitive Deficits

ApoE4 induces synaptic and ERG impairments in the retina of young targeted replacement apoE4 mice

A Nontransgenic Mouse Model Shows Inducible Amyloid-β (Aβ) Peptide Deposition and Elucidates the Role of Apolipoprotein E in the Amyloid Cascade

Involvement of the Apoer2 and Lrp1 receptors in mediating the pathological effects of ApoE4 in vivo

Hippocampus-Related Cognitive Impairments in Young apoE4 Targeted Replacement Mice

The effects of apolipoprotein E genotype, α-synuclein deficiency, and sex on brain synaptic and Alzheimer's disease–related pathology

VEGF Mediates ApoE4-Induced Neovascularization and Synaptic Pathology in the Choroid and Retina

ApoE ε4 is associated with eIF2α phosphorylation and impaired learning in young mice

ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice

ApoE4 impairs hippocampal plasticity isoform-specifically and blocks the environmental stimulation of synaptogenesis and memory

9-cis beta-carotene-enriched diet significantly improved cognition and decreased Alzheimer’s disease neuropathology and neuroinflammation in Alzheimer’s disease-like mouse models

Behavioral testing affects the phenotypic expression of APOE ε3 and APOE ε4 in targeted replacement mice and reduces the differences between them

Anatomical localization of protease‐activated receptor‐1 and protease‐mediated neuroglilal crosstalk on peri‐synaptic astrocytic endfeet

Environmental enrichment stimulates neurogenesis in apolipoprotein E3 and neuronal apoptosis in apolipoprotein E4 transgenic mice

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