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Characterization of factors that underlie transcriptional silencing in C. elegans oocytes

PLoS genetics, 2023-07, Vol.19 (7), p.e1010831-e1010831

2023

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MRN-dependent and independent pathways for recruitment of TOPBP1 to DNA double-strand breaks

PloS one, 2022-08, Vol.17 (8), p.e0271905-e0271905

2022

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Direct Binding to Replication Protein A (RPA)-coated Single-stranded DNA Allows Recruitment of the ATR Activator TopBP1 to Sites of DNA Damage

The Journal of biological chemistry, 2016-06, Vol.291 (25), p.13124-13131

2016

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Structure-function analysis of TOPBP1’s role in ATR signaling using the DSB-mediated ATR activation in Xenopus egg extracts (DMAX) system

Scientific reports, 2021-01, Vol.11 (1), p.467-467, Article 467

2021

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Zygotic Genome Activation Triggers Chromosome Damage and Checkpoint Signaling in C. elegans Primordial Germ Cells

Developmental cell, 2015-07, Vol.34 (1), p.85-95

2015

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Cell-Type Specific Responses to DNA Replication Stress in Early C. elegans Embryos

PloS one, 2016-10, Vol.11 (10), p.e0164601-e0164601

2016

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TopBP1 and DNA polymerase alpha-mediated recruitment of the 9-1-1 complex to stalled replication forks: Implications for a replication restart-based mechanism for ATR checkpoint activation

Cell cycle (Georgetown, Tex.), 2009-09, Vol.8 (18), p.2877-2884

2009

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Continued primer synthesis at stalled replication forks contributes to checkpoint activation

The Journal of cell biology, 2010-04, Vol.189 (2), p.233-246

2010

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Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts

The Journal of cell biology, 2005-12, Vol.171 (6), p.947-954

2005

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A global chromatin compaction pathway that represses germline gene expression during starvation

The Journal of cell biology, 2021-09, Vol.220 (9), p.1

2021

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Cyclin CYB-3 controls both S-phase and mitosis and is asymmetrically distributed in the early C. elegans embryo

Development (Cambridge), 2016-09, Vol.143 (17), p.3119-3127

Michael, W Matthew

2016

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NBS1 binds directly to TOPBP1 via disparate interactions between the NBS1 BRCT1 domain and the TOPBP1 BRCT1 and BRCT2 domains

DNA repair, 2023-03, Vol.123, p.103461-103461, Article 103461

2023

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Delineation of a minimal topoisomerase II binding protein 1 for regulated activation of ATR at DNA double-strand breaks

The Journal of biological chemistry, 2022-07, Vol.298 (7), p.101992-101992, Article 101992

2022

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TopBP1 and DNA polymerase-α directly recruit the 9-1-1 complex to stalled DNA replication forks

The Journal of cell biology, 2009-03, Vol.184 (6), p.793-804

2009

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Checkpoint silencing during the DNA damage response in Caenorhabditis elegans embryos

The Journal of cell biology, 2006-03, Vol.172 (7), p.999-1008

2006

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Biochemical analysis of TOPBP1 oligomerization

DNA repair, 2020-12, Vol.96, p.102973-102973, Article 102973

2020

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The Xenopus Xmus101 Protein Is Required for the Recruitment of Cdc45 to Origins of DNA Replication

The Journal of cell biology, 2002-11, Vol.159 (4), p.541-547

2002

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Programmed DNA Breaks Activate the Germline Genome in Caenorhabditis elegans

Developmental cell, 2018-08, Vol.46 (3), p.302-315.e5

2018

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Activation of the DNA Replication Checkpoint through RNA Synthesis by Primase

Science (American Association for the Advancement of Science), 2000-09, Vol.289 (5487), p.2133-2137

2000

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Regulated Proteolysis of DNA Polymerase η during the DNA-Damage Response in C. elegans

Molecular cell, 2008-12, Vol.32 (6), p.757-766

2008

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Control of DNA Replication by the Nucleus/Cytoplasm Ratio in Xenopus

The Journal of biological chemistry, 2013-10, Vol.288 (41), p.29382-29393

2013

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Development of the SapI/AarI Incision Mediated Plasmid Editing Method

Journal of molecular biology, 2018-05, Vol.430 (10), p.1426-1430

2018

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Importin β-dependent nuclear import of TopBP1 in ATR–Chk1 checkpoint in Xenopus egg extracts

Cellular signalling, 2014-05, Vol.26 (5), p.857-867

2014

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Speed and accuracy improvements in FLAASH atmospheric correction of hyperspectral imagery

Optical engineering, 2012-11, Vol.51 (11), p.111707

Perkins, Timothy

2012

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DNA Replication Is Required for the Checkpoint Response to Damaged DNA in Xenopus Egg Extracts

The Journal of cell biology, 2002-09, Vol.158 (5), p.863-872

2002

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Characterization of factors that underlie transcriptional silencing in C. elegans oocytes

MRN-dependent and independent pathways for recruitment of TOPBP1 to DNA double-strand breaks

Direct Binding to Replication Protein A (RPA)-coated Single-stranded DNA Allows Recruitment of the ATR Activator TopBP1 to Sites of DNA Damage

Structure-function analysis of TOPBP1’s role in ATR signaling using the DSB-mediated ATR activation in Xenopus egg extracts (DMAX) system

Zygotic Genome Activation Triggers Chromosome Damage and Checkpoint Signaling in C. elegans Primordial Germ Cells

Cell-Type Specific Responses to DNA Replication Stress in Early C. elegans Embryos

TopBP1 and DNA polymerase alpha-mediated recruitment of the 9-1-1 complex to stalled replication forks: Implications for a replication restart-based mechanism for ATR checkpoint activation

Continued primer synthesis at stalled replication forks contributes to checkpoint activation

Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts

A global chromatin compaction pathway that represses germline gene expression during starvation

Cyclin CYB-3 controls both S-phase and mitosis and is asymmetrically distributed in the early C. elegans embryo

NBS1 binds directly to TOPBP1 via disparate interactions between the NBS1 BRCT1 domain and the TOPBP1 BRCT1 and BRCT2 domains

Delineation of a minimal topoisomerase II binding protein 1 for regulated activation of ATR at DNA double-strand breaks

TopBP1 and DNA polymerase-α directly recruit the 9-1-1 complex to stalled DNA replication forks

Checkpoint silencing during the DNA damage response in Caenorhabditis elegans embryos

Biochemical analysis of TOPBP1 oligomerization

The Xenopus Xmus101 Protein Is Required for the Recruitment of Cdc45 to Origins of DNA Replication

Programmed DNA Breaks Activate the Germline Genome in Caenorhabditis elegans

Activation of the DNA Replication Checkpoint through RNA Synthesis by Primase

Regulated Proteolysis of DNA Polymerase η during the DNA-Damage Response in C. elegans

Control of DNA Replication by the Nucleus/Cytoplasm Ratio in Xenopus

Development of the SapI/AarI Incision Mediated Plasmid Editing Method

Importin β-dependent nuclear import of TopBP1 in ATR–Chk1 checkpoint in Xenopus egg extracts

Speed and accuracy improvements in FLAASH atmospheric correction of hyperspectral imagery

DNA Replication Is Required for the Checkpoint Response to Damaged DNA in Xenopus Egg Extracts

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