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4′,6-Dihydroxy-4-methoxyisoaurone Inhibits the HIF-1α Pathway Through Inhibition of Akt/mTOR/p70S6K/4E-BP1 Phosphorylation

Journal of Pharmacological Sciences, 2014/06/20, Vol.125(2), pp.193-201

2014

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4′,6-Dihydroxy-4-methoxyisoaurone inhibits TNF-α-induced NF-κB activation and expressions of NF-κB-regulated target gene products

Journal of pharmacological sciences, 2016-02, Vol.130 (2), p.43-50

2016

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Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-α-Induced NF-κB Activation

International journal of molecular sciences, 2017-07, Vol.18 (8), p.1619

2017

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CMV/AAT promoter of MAR-based episomal vector enhanced transgene expression in human hepatic cells

3 Biotech, 2023-11, Vol.13 (11), p.354-354, Article 354

2023

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Effects and mechanism of small molecule additives on recombinant protein in CHO cells

Applied microbiology and biotechnology, 2023-05, Vol.107 (9), p.2771-2781

2023

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Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways

Journal of ethnopharmacology, 2017-05, Vol.203, p.27-38

2017

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Fraxinellone has anticancer activity in vivo by inhibiting programmed cell death-ligand 1 expression by reducing hypoxia-inducible factor-1α and STAT3

Pharmacological research, 2018-09, Vol.135, p.166-180

2018

Volltextzugriff (PDF)

Zinc finger protein 91 positively regulates the production of IL‐1β in macrophages by activation of MAPKs and non‐canonical caspase‐8 inflammasome

British journal of pharmacology, 2018-12, Vol.175 (23), p.4338-4352

2018

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Chelidonine inhibits TNF-[alpha]-induced inflammation by suppressing the NF-[kappa]B pathways in HCT116 cells

Phytotherapy research, 2018-01, Vol.32 (1), p.65

2018

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Zinc finger protein 91 (ZFP91) activates HIF-1α via NF-κB/p65 to promote proliferation and tumorigenesis of colon cancer

Oncotarget, 2016-06, Vol.7 (24), p.36551-36562

2016

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Perillyl alcohol efficiently scavenges activity of cellular ROS and inhibits the translational expression of hypoxia-inducible factor-1α via mTOR/4E-BP1 signaling pathways

International immunopharmacology, 2016-10, Vol.39, p.1-9

2016

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Chelidonine inhibits TNF‐α‐induced inflammation by suppressing the NF‐κB pathways in HCT116 cells

Phytotherapy research, 2018-01, Vol.32 (1), p.65-75

2018

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Blockade of TNF-α-induced NF-κB signaling pathway and anti-cancer therapeutic response of dihydrotanshinone I

International immunopharmacology, 2015-09, Vol.28 (1), p.764-772

2015

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Artemisinin inhibits inflammatory response via regulating NF-κB and MAPK signaling pathways

Immunopharmacology and immunotoxicology, 2017-02, Vol.39 (1), p.28-36

2017

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Dictamnine promotes apoptosis and inhibits epithelial-mesenchymal transition, migration, invasion and proliferation by downregulating the HIF-1α and Slug signaling pathways

Chemico-biological interactions, 2018-12, Vol.296, p.134-144

2018

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Dihydromyricetin suppresses TNF-α-induced NF-κB activation and target gene expression

Molecular and cellular biochemistry, 2016-11, Vol.422 (1-2), p.11-20

2016

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Acevaltrate promotes apoptosis and inhibits proliferation by suppressing HIF-1α accumulation in cancer cells

International immunopharmacology, 2024-05, Vol.133, p.112066-112066, Article 112066

2024

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Imperatorin efficiently blocks TNF-α-mediated activation of ROS/PI3K/Akt/NF-κB pathway

Oncology reports, 2017-06, Vol.37 (6), p.3397-3404

2017

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Baicalein inhibits TNF-α-induced NF-κB activation and expression of NF-κB-regulated target gene products

Oncology reports, 2016-11, Vol.36 (5), p.2771-2776

2016

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Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1α signaling

Chemico-biological interactions, 2017-08, Vol.274, p.58-67

2017

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Amorfrutin A inhibits TNF-α-induced NF-κB activation and NF-κB-regulated target gene products

International immunopharmacology, 2014-07, Vol.21 (1), p.56-62

2014

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Malloapelta B suppresses LPS-induced NF-κB activation and NF-κB-regulated target gene products

International immunopharmacology, 2015-02, Vol.24 (2), p.147-152

2015

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Dihydrotanshinone I inhibits the translational expression of hypoxia-inducible factor-1α

Chemico-biological interactions, 2015-10, Vol.240, p.48-58

2015

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Amorfrutin A inhibits TNF-α induced JAK/STAT signaling, cell survival and proliferation of human cancer cells

Immunopharmacology and immunotoxicology, 2017-11, Vol.39 (6), p.338-347

2017

Volltextzugriff (PDF)

Kamebakaurin inhibits the expression of hypoxia-inducible factor-1[alpha] and its target genes to confer antitumor activity

Oncology reports, 2016-04, Vol.35 (4), p.2045

2016

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4′,6-Dihydroxy-4-methoxyisoaurone Inhibits the HIF-1α Pathway Through Inhibition of Akt/mTOR/p70S6K/4E-BP1 Phosphorylation

4′,6-Dihydroxy-4-methoxyisoaurone inhibits TNF-α-induced NF-κB activation and expressions of NF-κB-regulated target gene products

Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-α-Induced NF-κB Activation

CMV/AAT promoter of MAR-based episomal vector enhanced transgene expression in human hepatic cells

Effects and mechanism of small molecule additives on recombinant protein in CHO cells

Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways

Fraxinellone has anticancer activity in vivo by inhibiting programmed cell death-ligand 1 expression by reducing hypoxia-inducible factor-1α and STAT3

Zinc finger protein 91 positively regulates the production of IL‐1β in macrophages by activation of MAPKs and non‐canonical caspase‐8 inflammasome

Chelidonine inhibits TNF-[alpha]-induced inflammation by suppressing the NF-[kappa]B pathways in HCT116 cells

Zinc finger protein 91 (ZFP91) activates HIF-1α via NF-κB/p65 to promote proliferation and tumorigenesis of colon cancer

Perillyl alcohol efficiently scavenges activity of cellular ROS and inhibits the translational expression of hypoxia-inducible factor-1α via mTOR/4E-BP1 signaling pathways

Chelidonine inhibits TNF‐α‐induced inflammation by suppressing the NF‐κB pathways in HCT116 cells

Blockade of TNF-α-induced NF-κB signaling pathway and anti-cancer therapeutic response of dihydrotanshinone I

Artemisinin inhibits inflammatory response via regulating NF-κB and MAPK signaling pathways

Dictamnine promotes apoptosis and inhibits epithelial-mesenchymal transition, migration, invasion and proliferation by downregulating the HIF-1α and Slug signaling pathways

Dihydromyricetin suppresses TNF-α-induced NF-κB activation and target gene expression

Acevaltrate promotes apoptosis and inhibits proliferation by suppressing HIF-1α accumulation in cancer cells

Imperatorin efficiently blocks TNF-α-mediated activation of ROS/PI3K/Akt/NF-κB pathway

Baicalein inhibits TNF-α-induced NF-κB activation and expression of NF-κB-regulated target gene products

Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1α signaling

Amorfrutin A inhibits TNF-α-induced NF-κB activation and NF-κB-regulated target gene products

Malloapelta B suppresses LPS-induced NF-κB activation and NF-κB-regulated target gene products

Dihydrotanshinone I inhibits the translational expression of hypoxia-inducible factor-1α

Amorfrutin A inhibits TNF-α induced JAK/STAT signaling, cell survival and proliferation of human cancer cells

Kamebakaurin inhibits the expression of hypoxia-inducible factor-1[alpha] and its target genes to confer antitumor activity

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