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Spleen participation in partial MHC class II construct neuroprotection in stroke

CNS neuroscience & therapeutics, 2020-07, Vol.26 (7), p.663-669

2020

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A novel neurotherapeutic for multiple sclerosis, ischemic injury, methamphetamine addiction, and traumatic brain injury

Journal of neuroinflammation, 2019-01, Vol.16 (1), p.14-14, Article 14

2019

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Partial MHC class II constructs inhibit MIF/CD74 binding and downstream effects

European journal of immunology, 2013-05, Vol.43 (5), p.1309-1321

2013

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HLA-DRα1 constructs block CD74 expression and MIF effects in experimental autoimmune encephalomyelitis

The Journal of immunology (1950), 2014-05, Vol.192 (9), p.4164-4173

2014

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Sex-dependent treatment of chronic EAE with partial MHC class II constructs

Journal of neuroinflammation, 2017-05, Vol.14 (1), p.100-100, Article 100

2017

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Myelin oligodendrocyte glycoprotein‐35–55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA‐DR2‐transgenic mice

European journal of immunology, 2004-05, Vol.34 (5), p.1251-1261

2004

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A Novel Partial MHC Class II Construct, DRmQ, Inhibits Central and Peripheral Inflammatory Responses to Promote Neuroprotection in Experimental Stroke

Translational stroke research, 2020-08, Vol.11 (4), p.831-836

2020

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Increased CD74 binding and EAE treatment efficacy of a modified DRα1 molecular construct

Metabolic brain disease, 2019-02, Vol.34 (1), p.153-164

2019

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TCR‐like antibodies distinguish conformational and functional differences in two‐ versus four‐domain auto reactive MHC class II–peptide complexes

European journal of immunology, 2011-05, Vol.41 (5), p.1465-1479

2011

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Partial MHC class II constructs inhibit MIF / CD 74 binding and downstream effects

European journal of immunology, 2013-05, Vol.43 (5), p.1309-1321

2013

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Characterization of human platelet binding of recombinant T cell receptor ligand

Journal of neuroinflammation, 2010-11, Vol.7 (1), p.75-75, Article 75

2010

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Sex differences in EAE reveal common and distinct cellular and molecular components

Cellular immunology, 2021-01, Vol.359, p.104242-104242, Article 104242

2021

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MIF and D-DT are potential disease severity modifiers in male MS subjects

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (40), p.E8421-E8429

2017

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PD-L1 is required for estrogen-induced protection against severe EAE in IL-10 deficient mice1

Metabolic brain disease, 2023-02, Vol.38 (2), p.589-599

2023

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Production, Characterization, and Immunogenicity of a Soluble Rat Single Chain T Cell Receptor Specific for an Encephalitogenic Peptide

The Journal of biological chemistry, 2003-08, Vol.278 (33), p.30961-30970

2003

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Surviving the storm: Dealing with COVID-19

Cellular immunology, 2020-08, Vol.354, p.104153-104153, Article 104153

2020

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PD-L1 is required for estrogen-induced protection against severe EAE in IL-10 deficient mice 1

Metabolic brain disease, 2023-02, Vol.38 (2), p.589

2023

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Rationally designed mutations convert complexes of human recombinant T cell receptor ligands into monomers that retain biological activity

Journal of chemical technology and biotechnology (1986), 2005-01, Vol.80 (1), p.2-12

2005

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“Near Cure” treatment of severe acute EAE in MIF-1-deficient female and male mice with a bifunctional MHCII-derived molecular construct

Cellular immunology, 2022-08, Vol.378, p.104561-104561, Article 104561

2022

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Programmed cell death in cereal aleurone

Plant molecular biology, 2000-10, Vol.44 (3), p.255-266

2000

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Brief report: Enhanced DRα1-mMOG-35-55 treatment of severe EAE in MIF-1-deficient male mice

Cellular immunology, 2021-12, Vol.370, p.104439-104439, Article 104439

2021

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Predicted structure of MIF/CD74 and RTL1000/CD74 complexes

Metabolic brain disease, 2016-04, Vol.31 (2), p.249-255

2016

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Modeling of both shared and distinct interactions between MIF and its homologue D-DT with their common receptor CD74

Cytokine (Philadelphia, Pa.), 2016-12, Vol.88, p.62-70

2016

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CD4 aptamer–RORγt shRNA chimera inhibits IL-17 synthesis by human CD4+ T cells

Biochemical and biophysical research communications, 2014-10, Vol.452 (4), p.1040-1045

2014

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DRα1-MOG-35-55 Reduces Permanent Ischemic Brain Injury

Translational stroke research, 2017-06, Vol.8 (3), p.284-293

2017

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Spleen participation in partial MHC class II construct neuroprotection in stroke

A novel neurotherapeutic for multiple sclerosis, ischemic injury, methamphetamine addiction, and traumatic brain injury

Partial MHC class II constructs inhibit MIF/CD74 binding and downstream effects

HLA-DRα1 constructs block CD74 expression and MIF effects in experimental autoimmune encephalomyelitis

Sex-dependent treatment of chronic EAE with partial MHC class II constructs

Myelin oligodendrocyte glycoprotein‐35–55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA‐DR2‐transgenic mice

A Novel Partial MHC Class II Construct, DRmQ, Inhibits Central and Peripheral Inflammatory Responses to Promote Neuroprotection in Experimental Stroke

Increased CD74 binding and EAE treatment efficacy of a modified DRα1 molecular construct

TCR‐like antibodies distinguish conformational and functional differences in two‐ versus four‐domain auto reactive MHC class II–peptide complexes

Partial MHC class II constructs inhibit MIF / CD 74 binding and downstream effects

Characterization of human platelet binding of recombinant T cell receptor ligand

Sex differences in EAE reveal common and distinct cellular and molecular components

MIF and D-DT are potential disease severity modifiers in male MS subjects

PD-L1 is required for estrogen-induced protection against severe EAE in IL-10 deficient mice1

Production, Characterization, and Immunogenicity of a Soluble Rat Single Chain T Cell Receptor Specific for an Encephalitogenic Peptide

Surviving the storm: Dealing with COVID-19

PD-L1 is required for estrogen-induced protection against severe EAE in IL-10 deficient mice 1

Rationally designed mutations convert complexes of human recombinant T cell receptor ligands into monomers that retain biological activity

“Near Cure” treatment of severe acute EAE in MIF-1-deficient female and male mice with a bifunctional MHCII-derived molecular construct

Programmed cell death in cereal aleurone

Brief report: Enhanced DRα1-mMOG-35-55 treatment of severe EAE in MIF-1-deficient male mice

Predicted structure of MIF/CD74 and RTL1000/CD74 complexes

Modeling of both shared and distinct interactions between MIF and its homologue D-DT with their common receptor CD74

CD4 aptamer–RORγt shRNA chimera inhibits IL-17 synthesis by human CD4+ T cells

DRα1-MOG-35-55 Reduces Permanent Ischemic Brain Injury

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