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MK-1775, a Novel Wee1 Kinase Inhibitor, Radiosensitizes p53-Defective Human Tumor Cells

Clinical cancer research, 2011-09, Vol.17 (17), p.5638-5648

2011

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Therapeutic Delivery of miR-200c Enhances Radiosensitivity in Lung Cancer

Molecular therapy, 2014-08, Vol.22 (8), p.1494-1503

2014

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TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence

Clinical cancer research, 2012-01, Vol.18 (1), p.290-300

2012

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p16 Represses DNA Damage Repair via a Novel Ubiquitin-Dependent Signaling Cascade

Cancer research (Chicago, Ill.), 2022-03, Vol.82 (5), p.916-928

2022

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BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer

Clinical cancer research, 2018-02, Vol.24 (3), p.600-607

2018

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Histone Deacetylase Inhibitors Radiosensitize Human Melanoma Cells by Suppressing DNA Repair Activity

Clinical cancer research, 2005-07, Vol.11 (13), p.4912-4922

2005

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Gefitinib Radiosensitizes Non–Small Cell Lung Cancer Cells by Suppressing Cellular DNA Repair Capacity

Clinical cancer research, 2008-02, Vol.14 (4), p.1266-1273

2008

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Vorinostat, a histone deacetylase inhibitor, enhances the response of human tumor cells to ionizing radiation through prolongation of γ-H2AX foci

Molecular cancer therapeutics, 2006-08, Vol.5 (8), p.1967-1974

2006

Volltextzugriff (PDF)

MK-8776, a novel chk1 kinase inhibitor, radiosensitizes p53-defective human tumor cells

Oncotarget, 2016-11, Vol.7 (44), p.71660-71672

2016

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Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model

Molecular cancer therapeutics, 2015-12, Vol.14 (12), p.2901-2908

2015

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Identification of Cell Cycle Regulatory Genes as Principal Targets of p53-mediated Transcriptional Repression

The Journal of biological chemistry, 2006-09, Vol.281 (35), p.25134-25142

2006

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The role of apoptosis in radiation oncology

International journal of radiation biology, 2009-01, Vol.85 (2), p.107-115

2009

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Metabolic interrogation as a tool to optimize chemotherapeutic regimens

Oncotarget, 2017-03, Vol.8 (11), p.18154-18165

2017

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Integrative Analysis Identifies a Novel AXL-PI3 Kinase-PD-L1 Signaling Axis Associated with Radiation Resistance in Head and Neck Cancer

Clinical cancer research, 2017-06, Vol.23 (11), p.2713-2722

2017

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Proteomic Profiling Identifies PTK2/FAK as a Driver of Radioresistance in HPV-negative Head and Neck Cancer

Clinical cancer research, 2016-09, Vol.22 (18), p.4643-4650

2016

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Everything Old Is New Again: Using Nelfinavir to Radiosensitize Rectal Cancer

Clinical cancer research, 2016-04, Vol.22 (8), p.1834-1836

2016

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Tumor Irradiation Increases the Recruitment of Circulating Mesenchymal Stem Cells into the Tumor Microenvironment

Cancer research (Chicago, Ill.), 2007-12, Vol.67 (24), p.11687-11695

2007

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Wee-1 kinase inhibition overcomes cisplatin resistance associated with high-risk TP53 mutations in head and neck cancer through mitotic arrest followed by senescence

Molecular cancer therapeutics, 2015-02, Vol.14 (2), p.608-619

2015

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Targeting DNA damage response in head and neck cancers through abrogation of cell cycle checkpoints

International journal of radiation biology, 2021-08, Vol.97 (8), p.1121-1128

2021

Volltextzugriff (PDF)

Clonogenic cell survival assay

Methods in molecular medicine, 2005, Vol.110, p.21

2005

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Receptor signaling as a regulatory mechanism of DNA repair

Radiotherapy and oncology, 2009-09, Vol.92 (3), p.316-322

2009

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Translation Inhibitors Sensitize Prostate Cancer Cells to Apoptosis Induced by Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) by Activating c-Jun N-terminal Kinase

The Journal of biological chemistry, 2003-06, Vol.278 (23), p.20593-20602

2003

Volltextzugriff (PDF)

Niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase inhibitor, radiosensitizes human lung and breast cancer cells

Oncotarget, 2014-07, Vol.5 (13), p.5076-5086

2014

Volltextzugriff (PDF)

Targeted Apoptosis Activation with GrB/scFvMEL Modulates Melanoma Growth, Metastatic Spread, Chemosensitivity, and Radiosensitivity

Neoplasia (New York, N.Y.), 2006-02, Vol.8 (2), p.125-135

2006

Volltextzugriff (PDF)

Linking PTEN with genomic instability and DNA repair

Cell cycle (Georgetown, Tex.), 2009-08, Vol.8 (15), p.2322-2323

Meyn, Raymond E

2009

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MK-1775, a Novel Wee1 Kinase Inhibitor, Radiosensitizes p53-Defective Human Tumor Cells

Therapeutic Delivery of miR-200c Enhances Radiosensitivity in Lung Cancer

TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence

p16 Represses DNA Damage Repair via a Novel Ubiquitin-Dependent Signaling Cascade

BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer

Histone Deacetylase Inhibitors Radiosensitize Human Melanoma Cells by Suppressing DNA Repair Activity

Gefitinib Radiosensitizes Non–Small Cell Lung Cancer Cells by Suppressing Cellular DNA Repair Capacity

Vorinostat, a histone deacetylase inhibitor, enhances the response of human tumor cells to ionizing radiation through prolongation of γ-H2AX foci

MK-8776, a novel chk1 kinase inhibitor, radiosensitizes p53-defective human tumor cells

Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model

Identification of Cell Cycle Regulatory Genes as Principal Targets of p53-mediated Transcriptional Repression

The role of apoptosis in radiation oncology

Metabolic interrogation as a tool to optimize chemotherapeutic regimens

Integrative Analysis Identifies a Novel AXL-PI3 Kinase-PD-L1 Signaling Axis Associated with Radiation Resistance in Head and Neck Cancer

Proteomic Profiling Identifies PTK2/FAK as a Driver of Radioresistance in HPV-negative Head and Neck Cancer

Everything Old Is New Again: Using Nelfinavir to Radiosensitize Rectal Cancer

Tumor Irradiation Increases the Recruitment of Circulating Mesenchymal Stem Cells into the Tumor Microenvironment

Wee-1 kinase inhibition overcomes cisplatin resistance associated with high-risk TP53 mutations in head and neck cancer through mitotic arrest followed by senescence

Targeting DNA damage response in head and neck cancers through abrogation of cell cycle checkpoints

Clonogenic cell survival assay

Receptor signaling as a regulatory mechanism of DNA repair

Translation Inhibitors Sensitize Prostate Cancer Cells to Apoptosis Induced by Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) by Activating c-Jun N-terminal Kinase

Niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase inhibitor, radiosensitizes human lung and breast cancer cells

Targeted Apoptosis Activation with GrB/scFvMEL Modulates Melanoma Growth, Metastatic Spread, Chemosensitivity, and Radiosensitivity

Linking PTEN with genomic instability and DNA repair

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