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Pharmacogenetics and adverse drug reactions

The Lancet (British edition), 2000-11, Vol.356 (9242), p.1667-1671

Meyer, Urs A

2000

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The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans

The Journal of biological chemistry, 1994-06, Vol.269 (22), p.15419-15422

1994

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Personalized Medicine: A Personal View

Clinical pharmacology and therapeutics, 2012-03, Vol.91 (3), p.373-375

Meyer, U A

2012

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Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese

Molecular pharmacology, 1994-10, Vol.46 (4), p.594-598

1994

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Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification

The Lancet (British edition), 1990-09, Vol.336 (8714), p.529-532

1990

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Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4

Molecular pharmacology, 1989-07, Vol.36 (1), p.89-96

1989

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Molecular Mechanism of Slow Acetylation of Drugs and Carcinogens in Humans

Proceedings of the National Academy of Sciences - PNAS, 1991-06, Vol.88 (12), p.5237-5241

1991

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Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes

The Journal of biological chemistry, 1990-10, Vol.265 (28), p.17209-17214

1990

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Metabolic interactions of the proton-pump inhibitors lansoprazole, omeprazole and pantoprazole with other drugs

European journal of gastroenterology & hepatology, 1996-10, Vol.8 Suppl 1 (Supplement 1), p.S21-S25

Meyer, U A

1996

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The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene

American journal of human genetics, 1989-12, Vol.45 (6), p.889-904

1989

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Pharmacogenetics: The Slow, The Rapid, and the Ultrarapid

Proceedings of the National Academy of Sciences - PNAS, 1994-03, Vol.91 (6), p.1983-1984

Meyer, Urs A.

1994

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Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine

The Journal of biological chemistry, 1989-06, Vol.264 (18), p.10388-10395

1989

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Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes

Molecular pharmacology, 1991-02, Vol.39 (2), p.184-191

1991

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Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily

Biochemical journal, 1993-01, Vol.289 (2), p.533-538

1993

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Debrisoquine/sparteine hydroxylation genotype and phenotype: analysis of common mutations and alleles of CYP2D6 in a European population

DNA and cell biology, 1991-10, Vol.10 (8), p.545-558

1991

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Cyclosporine metabolism in human liver: Identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs

Clinical pharmacology and therapeutics, 1988-06, Vol.43 (6), p.630-635

1988

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Porphobilinogen deaminase deficiency in mice causes a neuropathy resembling that of human hepatic porphyria

Nature genetics, 1996-02, Vol.12 (2), p.195-199

1996

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Lidocaine metabolism in human liver microsomes by cytochrome P450IIIA4

Clinical pharmacology and therapeutics, 1989-11, Vol.46 (5), p.521-527

1989

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Antibodies against Human Cytochrome P-450db1 in Autoimmune Hepatitis Type II

Proceedings of the National Academy of Sciences - PNAS, 1988-11, Vol.85 (21), p.8256-8260

1988

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Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism

American journal of human genetics, 1991-05, Vol.48 (5), p.943-950

1991

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The molecular basis of genetic polymorphisms of drug metabolism

Journal of pharmacy and pharmacology, 1994-05, Vol.46 Suppl 1, p.409-415

Meyer, U A

1994

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Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily

The Journal of pharmacology and experimental therapeutics, 1990-01, Vol.252 (1), p.442

1990

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Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism

British journal of clinical pharmacology, 1993-12, Vol.36 (6), p.521-530

1993

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Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR

Archives of biochemistry and biophysics, 2005-01, Vol.433 (2), p.387-396

2005

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Cytokines, Oxidative Stress and Cellular Markers of Inflammation in Schizophrenia

Current topics in behavioral neurosciences, 2020, Vol.44, p.49-66

2020

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Pharmacogenetics and adverse drug reactions

The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans

Personalized Medicine: A Personal View

Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese

Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4

Molecular Mechanism of Slow Acetylation of Drugs and Carcinogens in Humans

Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes

Metabolic interactions of the proton-pump inhibitors lansoprazole, omeprazole and pantoprazole with other drugs

The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene

Pharmacogenetics: The Slow, The Rapid, and the Ultrarapid

Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine

Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes

Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily

Debrisoquine/sparteine hydroxylation genotype and phenotype: analysis of common mutations and alleles of CYP2D6 in a European population

Cyclosporine metabolism in human liver: Identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs

Porphobilinogen deaminase deficiency in mice causes a neuropathy resembling that of human hepatic porphyria

Lidocaine metabolism in human liver microsomes by cytochrome P450IIIA4

Antibodies against Human Cytochrome P-450db1 in Autoimmune Hepatitis Type II

Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism

The molecular basis of genetic polymorphisms of drug metabolism

Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily

Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism

Regulatory network of lipid-sensing nuclear receptors: roles for CAR, PXR, LXR, and FXR

Cytokines, Oxidative Stress and Cellular Markers of Inflammation in Schizophrenia

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