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The Autoimmunity-Associated Gene PTPN22 Potentiates Toll-like Receptor-Driven, Type 1 Interferon-Dependent Immunity

Immunity (Cambridge, Mass.), 2013-07, Vol.39 (1), p.111-122

2013

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Inflammatory cytokines as a third signal for T cell activation

Current opinion in immunology, 2010-06, Vol.22 (3), p.333-340

2010

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Antigen Processing and MHC-II Presentation by Dermal and Tumor-Infiltrating Dendritic Cells

The Journal of immunology (1950), 2009-03, Vol.182 (5), p.2726-2737

2009

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ICAM-1-dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation

The Journal of immunology (1950), 2013-10, Vol.191 (7), p.3681-3693

2013

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Autocrine IFN-γ promotes naive CD8 T cell differentiation and synergizes with IFN-α to stimulate strong function

The Journal of immunology (1950), 2012-07, Vol.189 (2), p.659-668

2012

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Cutting Edge: Type I IFNs Provide a Third Signal to CD8 T Cells to Stimulate Clonal Expansion and Differentiation

The Journal of immunology (1950), 2005-04, Vol.174 (8), p.4465-4469

2005

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Programming for CD8 T Cell Memory Development Requires IL-12 or Type I IFN

The Journal of immunology (1950), 2009-03, Vol.182 (5), p.2786-2794

2009

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Signals required for programming effector and memory development by CD8+ T cells

Immunological reviews, 2006-06, Vol.211 (1), p.81-92

2006

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Cutting edge: IL-12 and type I IFN differentially program CD8 T cells for programmed death 1 re-expression levels and tumor control

The Journal of immunology (1950), 2013-08, Vol.191 (3), p.1011-1015

2013

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Gene Regulation and Chromatin Remodeling by IL-12 and Type I IFN in Programming for CD8 T Cell Effector Function and Memory

The Journal of immunology (1950), 2009-08, Vol.183 (3), p.1695-1704

2009

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Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation

The Journal of experimental medicine, 2007-10, Vol.204 (11), p.2667-2677

2007

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In Vivo Augmentation of Tumor-Specific CTL Responses by Class I/Peptide Antigen Complexes on Microspheres (Large Multivalent Immunogen)

The Journal of immunology (1950), 2003-01, Vol.170 (1), p.228-235

2003

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Signal 3 determines tolerance versus full activation of naive CD8 T cells: dissociating proliferation and development of effector function

The Journal of experimental medicine, 2003-05, Vol.197 (9), p.1141-1151

2003

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Adoptive T Cell Therapy with IL-12-Preconditioned Low-Avidity T Cells Prevents Exhaustion and Results in Enhanced T Cell Activation, Enhanced Tumor Clearance, and Decreased Risk for Autoimmunity

The Journal of immunology (1950), 2020-09, Vol.205 (5), p.1449-1460

2020

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Activation-Induced Nonresponsiveness: A Th-Dependent Regulatory Checkpoint in the CTL Response

The Journal of immunology (1950), 2002-02, Vol.168 (3), p.1190-1197

2002

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IL-21 Promotes Differentiation of Naive CD8 T Cells to a Unique Effector Phenotype

Journal of Immunology, 2007-06, Vol.178 (12), p.7640-7648

2007

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CD8 T Cell Clonal Expansion and Development of Effector Function Require Prolonged Exposure to Antigen, Costimulation, and Signal 3 Cytokine

The Journal of immunology (1950), 2003-11, Vol.171 (10), p.5165-5171

2003

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The CD8 T cell response to vaccinia virus exhibits site-dependent heterogeneity of functional responses

International immunology, 2007-06, Vol.19 (6), p.733-743

2007

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Evolutionarily conserved resistance to phagocytosis observed in melanoma cells is insensitive to upregulation of pro-phagocytic signals and to CD47 blockade

Melanoma research, 2020-04, Vol.30 (2), p.147

2020

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Defective MHC Class II Presentation by Dendritic Cells Limits CD4 T Cell Help for Antitumor CD8 T Cell Responses

The Journal of immunology (1950), 2008-07, Vol.181 (1), p.155-164

2008

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CTLA-4 Blockade Reverses CD8 + T Cell Tolerance to Tumor by a CD4 + T Cell– and IL-2-Dependent Mechanism

Immunity (Cambridge, Mass.), 1999-10, Vol.11 (4), p.483-493

1999

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Enhancement of T-cell-Mediated Antitumor Response: Angiostatic Adjuvant to Immunotherapy against Cancer

Clinical cancer research, 2011-05, Vol.17 (10), p.3134-3145

2011

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Phase I Trial of Large Multivalent Immunogen Derived from Melanoma Lysates in Patients with Disseminated Melanoma

Clinical cancer research, 2004-01, Vol.10 (1), p.76-83

2004

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Inflammatory Cytokines Provide a Third Signal for Activation of Naive CD4+ and CD8+ T Cells

The Journal of immunology (1950), 1999-03, Vol.162 (6), p.3256-3262

1999

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Peptide Antigen Priming of Naive, But Not Memory, CD8 T Cells Requires a Third Signal That Can Be Provided by IL-12

The Journal of immunology (1950), 2002-06, Vol.168 (11), p.5521-5529

2002

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The Autoimmunity-Associated Gene PTPN22 Potentiates Toll-like Receptor-Driven, Type 1 Interferon-Dependent Immunity

Inflammatory cytokines as a third signal for T cell activation

Antigen Processing and MHC-II Presentation by Dermal and Tumor-Infiltrating Dendritic Cells

ICAM-1-dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation

Autocrine IFN-γ promotes naive CD8 T cell differentiation and synergizes with IFN-α to stimulate strong function

Cutting Edge: Type I IFNs Provide a Third Signal to CD8 T Cells to Stimulate Clonal Expansion and Differentiation

Programming for CD8 T Cell Memory Development Requires IL-12 or Type I IFN

Signals required for programming effector and memory development by CD8+ T cells

Cutting edge: IL-12 and type I IFN differentially program CD8 T cells for programmed death 1 re-expression levels and tumor control

Gene Regulation and Chromatin Remodeling by IL-12 and Type I IFN in Programming for CD8 T Cell Effector Function and Memory

Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation

In Vivo Augmentation of Tumor-Specific CTL Responses by Class I/Peptide Antigen Complexes on Microspheres (Large Multivalent Immunogen)

Signal 3 determines tolerance versus full activation of naive CD8 T cells: dissociating proliferation and development of effector function

Adoptive T Cell Therapy with IL-12-Preconditioned Low-Avidity T Cells Prevents Exhaustion and Results in Enhanced T Cell Activation, Enhanced Tumor Clearance, and Decreased Risk for Autoimmunity

Activation-Induced Nonresponsiveness: A Th-Dependent Regulatory Checkpoint in the CTL Response

IL-21 Promotes Differentiation of Naive CD8 T Cells to a Unique Effector Phenotype

CD8 T Cell Clonal Expansion and Development of Effector Function Require Prolonged Exposure to Antigen, Costimulation, and Signal 3 Cytokine

The CD8 T cell response to vaccinia virus exhibits site-dependent heterogeneity of functional responses

Evolutionarily conserved resistance to phagocytosis observed in melanoma cells is insensitive to upregulation of pro-phagocytic signals and to CD47 blockade

Defective MHC Class II Presentation by Dendritic Cells Limits CD4 T Cell Help for Antitumor CD8 T Cell Responses

CTLA-4 Blockade Reverses CD8 + T Cell Tolerance to Tumor by a CD4 + T Cell– and IL-2-Dependent Mechanism

Enhancement of T-cell-Mediated Antitumor Response: Angiostatic Adjuvant to Immunotherapy against Cancer

Phase I Trial of Large Multivalent Immunogen Derived from Melanoma Lysates in Patients with Disseminated Melanoma

Inflammatory Cytokines Provide a Third Signal for Activation of Naive CD4+ and CD8+ T Cells

Peptide Antigen Priming of Naive, But Not Memory, CD8 T Cells Requires a Third Signal That Can Be Provided by IL-12

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