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Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents

Accounts of chemical research, 2012-05, Vol.45 (5), p.756-766

2012

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Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents

Chemico-biological interactions, 2013-03, Vol.203 (1), p.81-84

2013

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Thiazolinium salt: an efficient catalyst for the Mukaiyama reaction

Tetrahedron letters, 2009-12, Vol.50 (52), p.7239-7241

2009

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Synthesis of 3-amino-thiochromanes from 4-benzyl 2-thiazolines, via an unprecedented intramolecular electrophilic aromatic substitution

Organic & biomolecular chemistry, 2010, Vol.8 (11), p.2520-2521

2010

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First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase

Chemical communications (Cambridge, England), 2011-05, Vol.47 (18), p.5295-5297

2011

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Potent 3‐Hydroxy‐2‐Pyridine Aldoxime Reactivators of Organophosphate‐Inhibited Cholinesterases with Predicted Blood–Brain Barrier Penetration

Chemistry : a European journal, 2018-07, Vol.24 (38), p.9675-9691

2018

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Phenyltetrahydroisoquinoline–Pyridinaldoxime Conjugates as Efficient Uncharged Reactivators for the Dephosphylation of Inhibited Human Acetylcholinesterase

Journal of medicinal chemistry, 2012-12, Vol.55 (23), p.10791-10795

2012

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An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice

Chemico-biological interactions, 2017-04, Vol.267 (1), p.11-16

2017

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Synthesis and in vitro evaluation of donepezil-based reactivators and analogues for nerve agent-inhibited human acetylcholinesterase

RSC advances, 2016-01, Vol.6 (22), p.17929-17940

2016

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Straightforward and efficient synthesis of 3-benzyloxy-4-bromopicolinate ester and 3-benzyloxy-5-bromopicolinate ester, common building blocks for pharmaceuticals and agrochemicals

Tetrahedron, 2011-11, Vol.67 (45), p.8757-8762

2011

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Synthetic Methodologies for the Preparation of β-Amino Thiols

European journal of organic chemistry, 2012-10, Vol.2012 (28), p.5423-5434

2012

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Synthetic Methodologies for the Preparation of [beta]-Amino Thiols

European journal of organic chemistry, 2012-10, Vol.2012 (28), p.5423

2012

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Efficient synthesis of primary 2-aminothiols from 2-aminoalcohols and methyldithioacetate

Tetrahedron letters, 2008-11, Vol.49 (46), p.6553-6555

2008

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Abstract 4745: Discovery of potent and selective Ros1 inhibitors with a unique DFG-out binding mode

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.4745-4745

2014

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Chemical Delivery System of Metaiodobenzylguanidine (MIBG) to the Central Nervous System

Journal of medicinal chemistry, 2010-02, Vol.53 (3), p.1281-1287

2010

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Versatile Synthesis of Secondary 2‐Amino Thiols and/or Their Disulfides via Thiazolinium Salts

European Journal of Organic Chemistry, 2009-09, Vol.2009 (25), p.4357-4364

2009

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Synthesis of secondary 2-amino thiols and/or their disulfides via thiazolinium salts

European journal of organic chemistry, 2009-07 (25), p.4357-4364

2009

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Synthesis of 3-amino-thiochromanes from 4-benzyl 2-thiazolines, via an unprecedented intramolecular electrophilic aromatic substitutionElectronic supplementary information (ESI) available: Experimental, spectral data, NMR spectra for compounds 3a,b and 6a-e, crystal data for (S)-3a and (R)-3a. CCDC reference numbers 766389 and 766390. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c003050c

2010-05

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Synthesis and in vitro evaluation of donepezil-based reactivators and analogues for nerve agent-inhibited human acetylcholinesteraseElectronic supplementary information (ESI) available. See DOI: 10.1039/c5ra25477a

2016-02

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ChemInform Abstract: Synthetic Methodologies for the Preparation of β-Amino Thiols

ChemInform, 2013-02, Vol.44 (9), p.no-no

2013

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ChemInform Abstract: Synthetic Methodologies for the Preparation of [beta]-Amino Thiols

ChemInform, 2013-02, Vol.44 (9), p.no

2013

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ChemInform Abstract: First Efficient Uncharged Reactivators for the Dephosphylation of Poisoned Human Acetylcholinesterase

ChemInform, 2011-08, Vol.42 (35), p.no-no

2011

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ChemInform Abstract: Efficient Synthesis of Primary 2-Aminothiols from 2-Aminoalcohols and Methyldithioacetate

ChemInform, 2009-03, Vol.40 (9), p.no-no

2009

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ChemInform Abstract: Versatile Synthesis of Secondary 2-Amino Thiols and/or Their Disulfides via Thiazolinium Salts

ChemInform, 2010-01, Vol.41 (3), p.no-no

2010

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ChemInform Abstract: Thiazolinium Salt: An Efficient Catalyst for the Mukaiyama Reaction

ChemInform, 2010-04, Vol.41 (15), p.no-no

2010

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Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents

Syntheses and in vitro evaluations of uncharged reactivators for human acetylcholinesterase inhibited by organophosphorus nerve agents

Thiazolinium salt: an efficient catalyst for the Mukaiyama reaction

Synthesis of 3-amino-thiochromanes from 4-benzyl 2-thiazolines, via an unprecedented intramolecular electrophilic aromatic substitution

First efficient uncharged reactivators for the dephosphylation of poisoned human acetylcholinesterase

Potent 3‐Hydroxy‐2‐Pyridine Aldoxime Reactivators of Organophosphate‐Inhibited Cholinesterases with Predicted Blood–Brain Barrier Penetration

Phenyltetrahydroisoquinoline–Pyridinaldoxime Conjugates as Efficient Uncharged Reactivators for the Dephosphylation of Inhibited Human Acetylcholinesterase

An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice

Synthesis and in vitro evaluation of donepezil-based reactivators and analogues for nerve agent-inhibited human acetylcholinesterase

Straightforward and efficient synthesis of 3-benzyloxy-4-bromopicolinate ester and 3-benzyloxy-5-bromopicolinate ester, common building blocks for pharmaceuticals and agrochemicals

Synthetic Methodologies for the Preparation of β-Amino Thiols

Synthetic Methodologies for the Preparation of [beta]-Amino Thiols

Efficient synthesis of primary 2-aminothiols from 2-aminoalcohols and methyldithioacetate

Abstract 4745: Discovery of potent and selective Ros1 inhibitors with a unique DFG-out binding mode

Chemical Delivery System of Metaiodobenzylguanidine (MIBG) to the Central Nervous System

Versatile Synthesis of Secondary 2‐Amino Thiols and/or Their Disulfides via Thiazolinium Salts

Synthesis of secondary 2-amino thiols and/or their disulfides via thiazolinium salts

Synthesis and in vitro evaluation of donepezil-based reactivators and analogues for nerve agent-inhibited human acetylcholinesteraseElectronic supplementary information (ESI) available. See DOI: 10.1039/c5ra25477a

ChemInform Abstract: Synthetic Methodologies for the Preparation of β-Amino Thiols

ChemInform Abstract: Synthetic Methodologies for the Preparation of [beta]-Amino Thiols

ChemInform Abstract: First Efficient Uncharged Reactivators for the Dephosphylation of Poisoned Human Acetylcholinesterase

ChemInform Abstract: Efficient Synthesis of Primary 2-Aminothiols from 2-Aminoalcohols and Methyldithioacetate

ChemInform Abstract: Versatile Synthesis of Secondary 2-Amino Thiols and/or Their Disulfides via Thiazolinium Salts

ChemInform Abstract: Thiazolinium Salt: An Efficient Catalyst for the Mukaiyama Reaction

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