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Copper dyshomoeostasis in Parkinson's disease: implications for pathogenesis and indications for novel therapeutics

Clinical science (1979), 2016-04, Vol.130 (8), p.565

2016

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Copper pathology in vulnerable brain regions in Parkinson's disease

Neurobiology of aging, 2014-04, Vol.35 (4), p.858-866

2014

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The molecular basis of copper-transport diseases

Trends in Molecular Medicine, 2001-02, Vol.7 (2), p.64-69

Mercer, Julian F.B

2001

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Metabolism and functions of copper in brain

Progress in neurobiology, 2014-05, Vol.116, p.33-57

2014

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Contributions of rat Ctr1 to the uptake and toxicity of copper and platinum anticancer drugs in dorsal root ganglion neurons

Biochemical pharmacology, 2013-01, Vol.85 (2), p.207-215

2013

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Role of Glutaredoxin1 and Glutathione in Regulating the Activity of the Copper-transporting P-type ATPases, ATP7A and ATP7B

The Journal of biological chemistry, 2010-08, Vol.285 (35), p.27111-27121

2010

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Trafficking of the copper-ATPases, ATP7A and ATP7B: Role in copper homeostasis

Archives of biochemistry and biophysics, 2007-07, Vol.463 (2), p.149-167

2007

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Copper-transporting P-type ATPase, ATP7A, confers multidrug resistance and its expression is related to resistance to SN-38 in clinical colon cancer

Cancer research (Chicago, Ill.), 2007-05, Vol.67 (10), p.4860-4868

2007

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Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

Brain research, 1999-09, Vol.842 (2), p.439-444

1999

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Missense Mutations in the Copper Transporter Gene ATP7A Cause X-Linked Distal Hereditary Motor Neuropathy

American journal of human genetics, 2010-03, Vol.86 (3), p.343-352

2010

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Clusterin and COMMD1 Independently Regulate Degradation of the Mammalian Copper ATPases ATP7A and ATP7B

The Journal of biological chemistry, 2012-01, Vol.287 (4), p.2485-2499

2012

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Altered intracellular localization and valosin-containing protein (p97 VCP) interaction underlie ATP7A-related distal motor neuropathy

Human molecular genetics, 2012-04, Vol.21 (8), p.1794-1807

2012

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Copper in disorders with neurological symptoms: Alzheimer’s, Menkes, and Wilson diseases

Brain research bulletin, 2001-05, Vol.55 (2), p.175-185

2001

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Molecular and Cellular Aspects of Copper Transport in Developing Mammals

The Journal of nutrition, 2003-05, Vol.133 (5), p.1481S-1484S

2003

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The molecular basis of copper homeostasis copper-related disorders

DNA and cell biology, 2002-04, Vol.21 (4), p.259

2002

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Mutations in the murine homologue of the Menkes gene in dappled and blotchy mice

Nature genetics, 1994-04, Vol.6 (4), p.374-378

1994

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The Menkes Protein (ATP7A; MNK) Cycles via the Plasma Membrane Both in Basal and Elevated Extracellular Copper Using a C-Terminal Di-Leucine Endocytic Signal

Human molecular genetics, 1999-10, Vol.8 (11), p.2107-2115

1999

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The Role of GMXCXXC Metal Binding Sites in the Copper-induced Redistribution of the Menkes Protein

The Journal of biological chemistry, 1999-04, Vol.274 (16), p.11170-11177

1999

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ATP7A Transgenic and Nontransgenic Mice Are Resistant to High Copper Exposure

The Journal of nutrition, 2008-04, Vol.138 (4), p.693-697

2008

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Effect of the toxic milk mutation (tx) on the function and intracellular localization of Wnd, the murine homologue of the Wilson copper ATPase

Human molecular genetics, 2001-02, Vol.10 (4), p.361-370

2001

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Effects of ATP7A overexpression in mice on copper transport and metabolism in lactation and gestation

Physiological reports, 2014-01, Vol.2 (1), p.e00195-n/a

2014

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Correction of the Copper Transport Defect of Menkes Patient Fibroblasts by Expression of the Menkes and Wilson ATPases

The Journal of biological chemistry, 1998-11, Vol.273 (47), p.31375-31380

1998

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Mammalian copper-transporting P-type ATPases, ATP7A and ATP7B: Emerging roles

The international journal of biochemistry & cell biology, 2010-02, Vol.42 (2), p.206-209

2010

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A phosphoglycerate mutase brain isoform ( PGAM 1) pseudogene is localized within the human Menkes disease gene ( ATP7A)

Gene, 1997-10, Vol.198 (1), p.37-41

1997

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Copper dyshomoeostasis in Parkinson's disease: implications for pathogenesis and indications for novel therapeutics

Copper pathology in vulnerable brain regions in Parkinson's disease

The molecular basis of copper-transport diseases

Metabolism and functions of copper in brain

Contributions of rat Ctr1 to the uptake and toxicity of copper and platinum anticancer drugs in dorsal root ganglion neurons

Role of Glutaredoxin1 and Glutathione in Regulating the Activity of the Copper-transporting P-type ATPases, ATP7A and ATP7B

Trafficking of the copper-ATPases, ATP7A and ATP7B: Role in copper homeostasis

Copper-transporting P-type ATPase, ATP7A, confers multidrug resistance and its expression is related to resistance to SN-38 in clinical colon cancer

Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

Missense Mutations in the Copper Transporter Gene ATP7A Cause X-Linked Distal Hereditary Motor Neuropathy

Clusterin and COMMD1 Independently Regulate Degradation of the Mammalian Copper ATPases ATP7A and ATP7B

Altered intracellular localization and valosin-containing protein (p97 VCP) interaction underlie ATP7A-related distal motor neuropathy

Copper in disorders with neurological symptoms: Alzheimer’s, Menkes, and Wilson diseases

Molecular and Cellular Aspects of Copper Transport in Developing Mammals

The molecular basis of copper homeostasis copper-related disorders

Mutations in the murine homologue of the Menkes gene in dappled and blotchy mice

The Menkes Protein (ATP7A; MNK) Cycles via the Plasma Membrane Both in Basal and Elevated Extracellular Copper Using a C-Terminal Di-Leucine Endocytic Signal

The Role of GMXCXXC Metal Binding Sites in the Copper-induced Redistribution of the Menkes Protein

ATP7A Transgenic and Nontransgenic Mice Are Resistant to High Copper Exposure

Effect of the toxic milk mutation (tx) on the function and intracellular localization of Wnd, the murine homologue of the Wilson copper ATPase

Effects of ATP7A overexpression in mice on copper transport and metabolism in lactation and gestation

Correction of the Copper Transport Defect of Menkes Patient Fibroblasts by Expression of the Menkes and Wilson ATPases

Mammalian copper-transporting P-type ATPases, ATP7A and ATP7B: Emerging roles

Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis

A phosphoglycerate mutase brain isoform ( PGAM 1) pseudogene is localized within the human Menkes disease gene ( ATP7A)

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