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Oral Treatment with CuII(atsm) Increases Mutant SOD1 In Vivo but Protects Motor Neurons and Improves the Phenotype of a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

The Journal of neuroscience, 2014-06, Vol.34 (23), p.8021-8031

2014

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Expression, Localisation and Hormone Regulation of the Human Copper Transporter hCTR1 in Placenta and Choriocarcinoma Jeg-3 Cells

Placenta (Eastbourne), 2006-09, Vol.27 (9), p.968-977

2006

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Defective Copper-Induced Trafficking and Localization of the Menkes Protein in Patients With Mild and Copper-Treated Classical Menkes Disease

Human molecular genetics, 1999-08, Vol.8 (8), p.1547-1555

1999

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Expression and Localization of Menkes and Wilson Copper Transporting ATPases in Human Placenta

Placenta (Eastbourne), 2004-07, Vol.25 (6), p.512-517

2004

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Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

Brain research, 1999-09, Vol.842 (2), p.439-444

1999

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The Menkes Protein (ATP7A; MNK) Cycles via the Plasma Membrane Both in Basal and Elevated Extracellular Copper Using a C-Terminal Di-Leucine Endocytic Signal

Human molecular genetics, 1999-10, Vol.8 (11), p.2107-2115

1999

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A C-Terminal Di-Leucine is Required for Localization of the Menkes Protein in the trans-Golgi Network

Human molecular genetics, 1998-12, Vol.7 (13), p.2063-2071

1998

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Menkes syndrome and animal models

The American journal of clinical nutrition, 1998-05, Vol.67 (5), p.1022S-1028S

Mercer, JF

1998

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The Toxic Milk Mouse is a Murine Model of Wilson Disease

Human molecular genetics, 1996-10, Vol.5 (10), p.1619-1624

1996

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Functional Analysis and Intracellular Localization of the Human Menkes Protein (MNK) Stably Expressed from a cDNA Construct in Chinese Hamster Ovary Cells (CHO-K1)

Human molecular genetics, 1998-08, Vol.7 (8), p.1293-1300

1998

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Molecular Basis of the Brindled Mouse Mutant (Mobr): A Murine Model of Menkes Disease

Human molecular genetics, 1997-07, Vol.6 (7), p.1037-1042

1997

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Gene amplification of the Menkes (MNK; ATP7A) P-type ATPase gene of CHO cells is associated with copper resistance and enhanced copper efflux

Human molecular genetics, 1995-11, Vol.4 (11), p.2117-2123

1995

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Endosomal trafficking of the Menkes copper ATPase ATP7A is mediated by vesicles containing the Rab7 and Rab5 GTPase proteins

Experimental cell research, 2003-12, Vol.291 (2), p.377-385

2003

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Mutations in the murine homologue of the Menkes gene in dappled and blotchy mice

Nature genetics, 1994-04, Vol.6 (4), p.374-378

1994

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Molecular Structure of the Menkes Disease Gene ( ATP7A)

Genomics (San Diego, Calif.), 1995-08, Vol.28 (3), p.462-469

1995

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A study of the role of metallothionein in the inherited copper toxicosis of dogs

Biochemical journal, 1986-06, Vol.236 (2), p.409-415

1986

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Cloning and characterization of cutE, a gene involved in copper transport in Escherichia coli

Journal of Bacteriology, 1991-11, Vol.173 (21), p.6742-6748

1991

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The murine mutation, lethal milk, results in production of zinc-deficient milk

The Journal of nutrition, 1992-06, Vol.122 (6), p.1214-1218

1992

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Rat ceruloplasmin. Molecular cloning and gene expression in liver, choroid plexus, yolk sac, placenta, and testis

The Journal of biological chemistry, 1987-02, Vol.262 (6), p.2875-2878

1987

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Regulation of 5-aminolevulinate synthase mRNA in different rat tissues

The Journal of biological chemistry, 1988-04, Vol.263 (11), p.5202-5209

1988

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Molecular biology of phenylalanine hydroxylase

Journal of inherited metabolic disease, 1986-06, Vol.9 (S2), p.206-208

1986

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Isolation and sequence of a cDNA clone which contains the complete coding region of rat phenylalanine hydroxylase. Structural homology with tyrosine hydroxylase, glucocorticoid regulation, and use of alternate polyadenylation sites

The Journal of biological chemistry, 1986-03, Vol.261 (9), p.4148-4153

1986

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Hepatic metallothionein gene expression in toxic milk mice

The Journal of nutrition, 1992-06, Vol.122 (6), p.1254-1259

1992

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The toxic milk mouse does have elevated hepatic metallothionein mRNA

Biochemical journal, 1994-11, Vol.304 ( Pt 1) (1), p.317-318

1994

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Variation in the amounts of hepatic copper, zinc and metallothionein mRNA during development in the rat

Biochemical journal, 1986-08, Vol.238 (1), p.23-27

1986

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Oral Treatment with CuII(atsm) Increases Mutant SOD1 In Vivo but Protects Motor Neurons and Improves the Phenotype of a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

Expression, Localisation and Hormone Regulation of the Human Copper Transporter hCTR1 in Placenta and Choriocarcinoma Jeg-3 Cells

Defective Copper-Induced Trafficking and Localization of the Menkes Protein in Patients With Mild and Copper-Treated Classical Menkes Disease

Expression and Localization of Menkes and Wilson Copper Transporting ATPases in Human Placenta

Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

The Menkes Protein (ATP7A; MNK) Cycles via the Plasma Membrane Both in Basal and Elevated Extracellular Copper Using a C-Terminal Di-Leucine Endocytic Signal

A C-Terminal Di-Leucine is Required for Localization of the Menkes Protein in the trans-Golgi Network

Menkes syndrome and animal models

The Toxic Milk Mouse is a Murine Model of Wilson Disease

Functional Analysis and Intracellular Localization of the Human Menkes Protein (MNK) Stably Expressed from a cDNA Construct in Chinese Hamster Ovary Cells (CHO-K1)

Molecular Basis of the Brindled Mouse Mutant (Mobr): A Murine Model of Menkes Disease

Gene amplification of the Menkes (MNK; ATP7A) P-type ATPase gene of CHO cells is associated with copper resistance and enhanced copper efflux

Endosomal trafficking of the Menkes copper ATPase ATP7A is mediated by vesicles containing the Rab7 and Rab5 GTPase proteins

Mutations in the murine homologue of the Menkes gene in dappled and blotchy mice

Molecular Structure of the Menkes Disease Gene ( ATP7A)

A study of the role of metallothionein in the inherited copper toxicosis of dogs

Cloning and characterization of cutE, a gene involved in copper transport in Escherichia coli

The murine mutation, lethal milk, results in production of zinc-deficient milk

Rat ceruloplasmin. Molecular cloning and gene expression in liver, choroid plexus, yolk sac, placenta, and testis

Regulation of 5-aminolevulinate synthase mRNA in different rat tissues

Molecular biology of phenylalanine hydroxylase

Isolation and sequence of a cDNA clone which contains the complete coding region of rat phenylalanine hydroxylase. Structural homology with tyrosine hydroxylase, glucocorticoid regulation, and use of alternate polyadenylation sites

Hepatic metallothionein gene expression in toxic milk mice

The toxic milk mouse does have elevated hepatic metallothionein mRNA

Variation in the amounts of hepatic copper, zinc and metallothionein mRNA during development in the rat

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