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Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin

Nature immunology, 2021-02, Vol.22 (2), p.154-165

2021

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Splice factor polypyrimidine tract-binding protein 1 (Ptbp1) primes endothelial inflammation in atherogenic disturbed flow conditions

Proceedings of the National Academy of Sciences - PNAS, 2022-07, Vol.119 (30), p.1-e2122227119

2022

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Interleukin-17 directly stimulates tumor infiltrating Tregs to prevent cancer development

Frontiers in immunology, 2024-06, Vol.15, p.1408710

2024

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Antigen-specific downregulation of miR-150 in CD4 T cells promotes cell survival

Frontiers in immunology, 2023-01, Vol.14, p.1102403-1102403

2023

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CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy

The Journal of experimental medicine, 2023-09, Vol.220 (9)

2023

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CD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells to program cytotoxic Th1 differentiation

The Journal of immunology (1950), 2011-10, Vol.187 (7), p.3555-3564

2011

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GRK2 enforces androgen receptor dependence in the prostate and prostate tumors

Oncogene, 2020-03, Vol.39 (11), p.2424-2436

2020

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Roles of heat-shock proteins in antigen presentation and cross-presentation

Current Opinion in Immunology, 2002-02, Vol.14 (1), p.45-51

2002

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Presensitizing with a Toll-like receptor 3 ligand impairs CD8 T-cell effector differentiation and IL-33 responsiveness

Proceedings of the National Academy of Sciences - PNAS, 2012-06, Vol.109 (26), p.10486-10491

2012

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A Refined Bead-Free Method to Identify Astrocytic Exosomes in Primary Glial Cultures and Blood Plasma

Frontiers in neuroscience, 2017-06, Vol.11, p.335-335

2017

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Nicotinamide breaks effector CD8 T cell responses by targeting mTOR signaling

iScience, 2022-03, Vol.25 (3), p.103932-103932, Article 103932

2022

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Costimulation Induces CD4 T Cell Antitumor Immunity via an Innate-like Mechanism

Cell reports (Cambridge), 2019-04, Vol.27 (5), p.1434-1445.e3

2019

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Direct CD137 costimulation of CD8 T cells promotes retention and innate-like function within nascent atherogenic foci

American journal of physiology. Heart and circulatory physiology, 2019-06, Vol.316 (6), p.H1480-H1494

2019

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Optimal CD8+ T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape

Nature communications, 2022-06, Vol.13 (1), p.3540-3540, Article 3540

2022

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Heat Shock Proteins Come of Age: Primitive Functions Acquire New Roles in an Adaptive World

Immunity, 1998-06, Vol.8 (6), p.657-665

1998

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Optimal CD8+ T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape

The Journal of immunology (1950), 2022-05, Vol.208 (1_Supplement), p.55-55.11

2022

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A benzimidazole inhibitor attenuates sterile inflammation induced in a model of systemic autoinflammation in female mice

Scientific reports, 2020-07, Vol.10 (1), p.12100, Article 12100

2020

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Characterizing the inflammatory response in esophageal mucosal biopsies in children with eosinophilic esophagitis

Clinical & translational immunology, 2016-07, Vol.5 (7), p.e88-n/a

2016

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The Oxazolidinone Derivative Locostatin Induces Cytokine Appeasement

The Journal of immunology (1950), 2009-12, Vol.183 (11), p.7489-7496

2009

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Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis

Immunity (Cambridge, Mass.), 2018-09, Vol.49 (3), p.413-426.e5

2018

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Saturation, Competition, and Specificity in Interaction of Heat Shock Proteins (hsp) gp96, hsp90, and hsp70 with CD11b+ Cells

The Journal of immunology (1950), 2000-09, Vol.165 (5), p.2582-2587

2000

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Optimal CD4 T cell priming after LPS‐based adjuvanticity with CD134 costimulation relies on CXCL9 production

Journal of leukocyte biology, 2017-07, Vol.102 (1), p.57-69

2017

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Evaluating the glycolytic potential of mouse costimulated effector CD8+ T cells ex vivo

STAR protocols, 2022-06, Vol.3 (2), p.101441-101441, Article 101441

2022

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IRAK4 is an immunological checkpoint in neuropsychiatric systemic lupus erythematosus

Scientific reports, 2024-07, Vol.14 (1), p.16393-11, Article 16393

2024

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Therapeutic blockade of CD54 attenuates pulmonary barrier damage in T cell-induced acute lung injury

American journal of physiology. Lung cellular and molecular physiology, 2017-07, Vol.313 (1), p.L177-L191

2017

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Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin

Splice factor polypyrimidine tract-binding protein 1 (Ptbp1) primes endothelial inflammation in atherogenic disturbed flow conditions

Interleukin-17 directly stimulates tumor infiltrating Tregs to prevent cancer development

Antigen-specific downregulation of miR-150 in CD4 T cells promotes cell survival

CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy

CD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells to program cytotoxic Th1 differentiation

GRK2 enforces androgen receptor dependence in the prostate and prostate tumors

Roles of heat-shock proteins in antigen presentation and cross-presentation

Presensitizing with a Toll-like receptor 3 ligand impairs CD8 T-cell effector differentiation and IL-33 responsiveness

A Refined Bead-Free Method to Identify Astrocytic Exosomes in Primary Glial Cultures and Blood Plasma

Nicotinamide breaks effector CD8 T cell responses by targeting mTOR signaling

Costimulation Induces CD4 T Cell Antitumor Immunity via an Innate-like Mechanism

Direct CD137 costimulation of CD8 T cells promotes retention and innate-like function within nascent atherogenic foci

Optimal CD8+ T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape

Heat Shock Proteins Come of Age: Primitive Functions Acquire New Roles in an Adaptive World

Optimal CD8+ T cell effector function requires costimulation-induced RNA-binding proteins that reprogram the transcript isoform landscape

A benzimidazole inhibitor attenuates sterile inflammation induced in a model of systemic autoinflammation in female mice

Characterizing the inflammatory response in esophageal mucosal biopsies in children with eosinophilic esophagitis

The Oxazolidinone Derivative Locostatin Induces Cytokine Appeasement

Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis

Saturation, Competition, and Specificity in Interaction of Heat Shock Proteins (hsp) gp96, hsp90, and hsp70 with CD11b+ Cells

Optimal CD4 T cell priming after LPS‐based adjuvanticity with CD134 costimulation relies on CXCL9 production

Evaluating the glycolytic potential of mouse costimulated effector CD8+ T cells ex vivo

IRAK4 is an immunological checkpoint in neuropsychiatric systemic lupus erythematosus

Therapeutic blockade of CD54 attenuates pulmonary barrier damage in T cell-induced acute lung injury

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