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Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance

Nature communications, 2018-05, Vol.9 (1), p.1849-14, Article 1849

2018

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Modeling Therapy Resistance in BRCA1/2 -Mutant Cancers

Molecular cancer therapeutics, 2017-09, Vol.16 (9), p.2022-2034

2017

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ATR Is a Therapeutic Target in Synovial Sarcoma

Cancer research (Chicago, Ill.), 2017-12, Vol.77 (24), p.7014-7026

2017

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A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors

Scientific reports, 2019-01, Vol.9 (1), p.201, Article 201

2019

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The Signature Amino Acid Residue Serine 31 of HIV-1C Tat Potentiates an Activated Phenotype in Endothelial Cells

Frontiers in immunology, 2020-09, Vol.11, p.529614-529614

2020

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Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction

Journal of medicinal chemistry, 2010-03, Vol.53 (5), p.2215-2226

2010

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Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites

The Journal of biological chemistry, 2003-02, Vol.278 (9), p.7206-7214

2003

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The grafting of universal T-helper epitopes enhances immunogenicity of HIV-1 Tat concurrently improving its safety profile

PloS one, 2014-12, Vol.9 (12), p.e114155-e114155

2014

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Hi-JAK-ing the ubiquitin system: The design and physicochemical optimisation of JAK PROTACs

Bioorganic & medicinal chemistry, 2020-03, Vol.28 (5), p.115326, Article 115326

2020

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Astrocytes mediate HIV‐1 Tat‐induced neuronal damage via ligand‐gated ion channel P2X7R

Journal of neurochemistry, 2015-02, Vol.132 (4), p.464-476

2015

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Hammerhead ribozyme-mediated silencing of the mutant fibrillin-1 of tight skin mouse: Insight into the functional role of mutant fibrillin-1

Experimental cell research, 2006-05, Vol.312 (9), p.1463-1474

2006

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PTAP motif duplication in the p6 Gag protein confers a replication advantage on HIV-1 subtype C

The Journal of biological chemistry, 2018-07, Vol.293 (30), p.11687-11708

2018

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Abstract 2975: Synthetic lethality in synovial sarcoma: SS18-SSX fusions and DNA damage response (DDR) inhibitors

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2975-2975

2018

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Abstract NTOC-093: SYNTHETIC LETHAL APPROACHES TO TARGET ARID1A DEFICIENT OVARIAN CANCERS

Clinical cancer research, 2017-06, Vol.23 (11_Supplement), p.NTOC-093-NTOC-093

2017

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RET mutation status in medullary thyroid cancer(MTC) patients and the significance of genetic screening for mutations in their immediate relatives--a preliminary report

Indian journal of pathology & microbiology, 2005-04, Vol.48 (2), p.161

2005

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Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

Scientific reports, 2018-07, Vol.8 (1), p.10614-9, Article 10614

2018

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Abstract 2986: E-cadherin/ROS1 inhibitor synthetic lethality in breast cancer

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2986-2986

2018

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Telomerase and telomere length in normal and malignant human endometrium as prognostic markers

Indian journal of pathology & microbiology, 2003-07, Vol.46 (3), p.394

2003

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Candidate drug therapies for molecularly defined subgroups of esophageal cancer identified from high-throughput drug screening

Journal of clinical oncology, 2014-05, Vol.32 (15_suppl), p.4039-4039

2014

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The Evolving Profile of the Signature Amino Acid Residues in HIV-1 Subtype C Tat

AIDS research and human retroviruses, 2016-05, Vol.32 (5), p.503

2016

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Design and discovery of 3-aryl-5-substituted-isoquinolin-1-ones as potent tankyrase inhibitorsElectronic supplementary information (ESI) available: For complete experimental details for the TNKS homology model generation and virtual screen, chemical synthesis, biological assays and X-ray crystallography see ESI. The PDB accession codes for the X-ray co-crystal structure of TNKS + 12, TNKS + 21 and TNKS + 23 are 4UW1, 4U6A and 4UUH, respectively. See DOI: 10.1039/c5md00210a

2015-09

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The Grafting of Universal T-Helper Epitopes Enhances Immunogenicity of HIV-1 Tat Concurrently Improving Its Safety Profile: e114155

PloS one, 2014-12, Vol.9 (12)

2014

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Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance

Modeling Therapy Resistance in BRCA1/2 -Mutant Cancers

ATR Is a Therapeutic Target in Synovial Sarcoma

A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors

The Signature Amino Acid Residue Serine 31 of HIV-1C Tat Potentiates an Activated Phenotype in Endothelial Cells

Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction

Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites

The grafting of universal T-helper epitopes enhances immunogenicity of HIV-1 Tat concurrently improving its safety profile

Hi-JAK-ing the ubiquitin system: The design and physicochemical optimisation of JAK PROTACs

Astrocytes mediate HIV‐1 Tat‐induced neuronal damage via ligand‐gated ion channel P2X7R

Hammerhead ribozyme-mediated silencing of the mutant fibrillin-1 of tight skin mouse: Insight into the functional role of mutant fibrillin-1

E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer

PTAP motif duplication in the p6 Gag protein confers a replication advantage on HIV-1 subtype C

Abstract 2975: Synthetic lethality in synovial sarcoma: SS18-SSX fusions and DNA damage response (DDR) inhibitors

Abstract NTOC-093: SYNTHETIC LETHAL APPROACHES TO TARGET ARID1A DEFICIENT OVARIAN CANCERS

RET mutation status in medullary thyroid cancer(MTC) patients and the significance of genetic screening for mutations in their immediate relatives--a preliminary report

Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

Abstract 2986: E-cadherin/ROS1 inhibitor synthetic lethality in breast cancer

Telomerase and telomere length in normal and malignant human endometrium as prognostic markers

Candidate drug therapies for molecularly defined subgroups of esophageal cancer identified from high-throughput drug screening

The Evolving Profile of the Signature Amino Acid Residues in HIV-1 Subtype C Tat

Author Correction: Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

Design and discovery of 3-aryl-5-substituted-isoquinolin-1-ones as potent tankyrase inhibitors

The Grafting of Universal T-Helper Epitopes Enhances Immunogenicity of HIV-1 Tat Concurrently Improving Its Safety Profile: e114155

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