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Targeting of ADAMTS5's ancillary domain with the recombinant mAb CRB0017 ameliorates disease progression in a spontaneous murine model of osteoarthritis

Osteoarthritis and cartilage, 2013-11, Vol.21 (11), p.1807-1810

2013

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Glutamate signaling in chondrocytes and the potential involvement of NMDA receptors in cell proliferation and inflammatory gene expression

Osteoarthritis and cartilage, 2009-08, Vol.17 (8), p.1076-1083

2009

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Andolast Acts at Different Cellular Levels to Inhibit Immunoglobulin E Synthesis

International journal of immunopathology and pharmacology, 2009, Vol.22 (1), p.85-94

2009

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N-terminal anthranoyl-phenylalanine derivatives as CCK1 receptor antagonists: the final approach

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2005-09, Vol.1 (5), p.501-517

2005

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Analgesic efficacy of CR4056, a novel imidazoline-2 receptor ligand, in rat models of inflammatory and neuropathic pain

Journal of pain research, 2011, Vol.4 (default), p.111-125

2011

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Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure

Journal of medicinal chemistry, 2004-05, Vol.47 (10), p.2574-2586

2004

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Effect of three nonpeptide cholecystokinin antagonists on human isolated gallbladder

Digestive diseases and sciences, 2001-12, Vol.46 (12), p.2773-2778

2001

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Anthranilic acid based CCK1 receptor antagonists : preliminary investigation on their second touch point

European journal of medicinal chemistry, 2005-06, Vol.40 (6), p.563-581

2005

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Anthranilic acid based CCK1 antagonists: the 2-indole moiety may represent a needle according to the recent homonymous concept

European journal of medicinal chemistry, 2004, Vol.39 (1), p.85-97

2004

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Anthranilic acid derivatives : A new class of non-peptide CCK1 receptor antagonists

Bioorganic & medicinal chemistry, 2003-03, Vol.11 (5), p.741-751

2003

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Novel potent 5-HT3 receptor ligands based on the pyrrolidone structure: Synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities

Bioorganic & medicinal chemistry, 2002-03, Vol.10 (3), p.779-801

2002

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Novel Potent and Selective Central 5-HT3 Receptor Ligands Provided with Different Intrinsic Efficacy. 1. Mapping the Central 5-HT3 Receptor Binding Site by Arylpiperazine Derivatives

Journal of medicinal chemistry, 1998-02, Vol.41 (5), p.728-741

1998

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Characterization of antisecretory and antiulcer activity of CR 2945, a new potent and selective gastrin/CCK(B) receptor antagonist

European journal of pharmacology, 1999-03, Vol.369 (1), p.81

1999

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Characterization of antisecretory and antiulcer activity of CR 2945, a new potent and selective gastrin/CCKB receptor antagonist

European journal of pharmacology, 1999-03, Vol.369 (1), p.81-90

1999

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Further Studies on the Interaction of the 5-Hydroxytryptamine sub(3) (5-HT sub(3)) Receptor with Arylpiperazine Ligands. Development of a New 5-HT sub(3) Receptor Ligand Showing Potent Acetylcholinesterase Inhibitory Properties

Journal of medicinal chemistry, 2005-05, Vol.48 (10), p.3564-3575

2005

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Novel Potent and Selective Central 5-HT3 Receptor Ligands Provided with Different Intrinsic Efficacy. 2. Molecular Basis of the Intrinsic Efficacy of Arylpiperazine Derivatives at the Central 5-HT3 Receptors

Journal of medicinal chemistry, 1999-05, Vol.42 (9), p.1556-1575

1999

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CR 2945: a novel CCKB receptor antagonist with anxiolytic-like activity

Behavioural pharmacology, 1998-05, Vol.9 (3), p.183-194

1998

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Novel potent 5-HT3 receptor ligands based on the pyrrolidone structure. effects of the quaternization of the basic nitrogen on the interaction with 5-HT3 receptor

Bioorganic & medicinal chemistry, 2002-08, Vol.10 (8), p.2681-2691

2002

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Synthesis, Biological Evaluation, and Quantitative Receptor Docking Simulations of 2-[(Acylamino)ethyl]-1,4-benzodiazepines as Novel Tifluadom-like Ligands with High Affinity and Selectivity for κ-Opioid Receptors

Journal of medicinal chemistry, 1996-02, Vol.39 (4), p.860-872

1996

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Cytosolic Ca2+ evaluation in rabbit parietal cells : a novel method to screen gastrin receptor antagonists

European journal of pharmacology, 1996-06, Vol.306 (1-3), p.325-334

1996

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Central pharmacological activities and opiate receptor binding studies of some dermorphin analogs

Peptides (New York, N.Y. : 1980), 1985, Vol.6, p.155-159

1985

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Structure−Antigastrin Activity Relationships of New Spiroglumide Amido Acid Derivatives

Journal of medicinal chemistry, 1996-01, Vol.39 (1), p.135-142

1996

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Structure-antigastrin activity relationships of new (R)-4-benzamido-5-oxopentanoic acid derivatives

Journal of medicinal chemistry, 1992-01, Vol.35 (1), p.28-38

1992

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Methylazoxymethanol-induced microencephaly: persistent increase of cortical somatostatin-like immunoreactivity

Brain research. Developmental brain research, 1989-05, Vol.47 (1), p.156-159

1989

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Binding studies of dermorphin and its L-form on rat brain opioid receptors

Pharmacological research communications, 1987-02, Vol.19 (2), p.173-181

1987

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Targeting of ADAMTS5's ancillary domain with the recombinant mAb CRB0017 ameliorates disease progression in a spontaneous murine model of osteoarthritis

Glutamate signaling in chondrocytes and the potential involvement of NMDA receptors in cell proliferation and inflammatory gene expression

Andolast Acts at Different Cellular Levels to Inhibit Immunoglobulin E Synthesis

N-terminal anthranoyl-phenylalanine derivatives as CCK1 receptor antagonists: the final approach

Analgesic efficacy of CR4056, a novel imidazoline-2 receptor ligand, in rat models of inflammatory and neuropathic pain

Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure

Effect of three nonpeptide cholecystokinin antagonists on human isolated gallbladder

Anthranilic acid based CCK1 receptor antagonists : preliminary investigation on their second touch point

Anthranilic acid based CCK1 antagonists: the 2-indole moiety may represent a needle according to the recent homonymous concept

Anthranilic acid derivatives : A new class of non-peptide CCK1 receptor antagonists

Novel potent 5-HT3 receptor ligands based on the pyrrolidone structure: Synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities

Novel Potent and Selective Central 5-HT3 Receptor Ligands Provided with Different Intrinsic Efficacy. 1. Mapping the Central 5-HT3 Receptor Binding Site by Arylpiperazine Derivatives

Characterization of antisecretory and antiulcer activity of CR 2945, a new potent and selective gastrin/CCK(B) receptor antagonist

Characterization of antisecretory and antiulcer activity of CR 2945, a new potent and selective gastrin/CCKB receptor antagonist

Further Studies on the Interaction of the 5-Hydroxytryptamine sub(3) (5-HT sub(3)) Receptor with Arylpiperazine Ligands. Development of a New 5-HT sub(3) Receptor Ligand Showing Potent Acetylcholinesterase Inhibitory Properties

Novel Potent and Selective Central 5-HT3 Receptor Ligands Provided with Different Intrinsic Efficacy. 2. Molecular Basis of the Intrinsic Efficacy of Arylpiperazine Derivatives at the Central 5-HT3 Receptors

CR 2945: a novel CCKB receptor antagonist with anxiolytic-like activity

Novel potent 5-HT3 receptor ligands based on the pyrrolidone structure. effects of the quaternization of the basic nitrogen on the interaction with 5-HT3 receptor

Synthesis, Biological Evaluation, and Quantitative Receptor Docking Simulations of 2-[(Acylamino)ethyl]-1,4-benzodiazepines as Novel Tifluadom-like Ligands with High Affinity and Selectivity for κ-Opioid Receptors

Cytosolic Ca2+ evaluation in rabbit parietal cells : a novel method to screen gastrin receptor antagonists

Central pharmacological activities and opiate receptor binding studies of some dermorphin analogs

Structure−Antigastrin Activity Relationships of New Spiroglumide Amido Acid Derivatives

Structure-antigastrin activity relationships of new (R)-4-benzamido-5-oxopentanoic acid derivatives

Methylazoxymethanol-induced microencephaly: persistent increase of cortical somatostatin-like immunoreactivity

Binding studies of dermorphin and its L-form on rat brain opioid receptors

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