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Liver X receptor agonists as potential therapeutic agents for dyslipidemia and atherosclerosis

Arteriosclerosis, thrombosis, and vascular biology, 2003-07, Vol.23 (7), p.1169

2003

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Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors

Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (9), p.2522-2526

2013

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nuclear membrane organization of leukotriene synthesis

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (51), p.20434-20439

2008

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Different roles of liver X receptor α and β in lipid metabolism: Effects of an α-selective and a dual agonist in mice deficient in each subtype

Biochemical pharmacology, 2006-02, Vol.71 (4), p.453-463

2006

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27-Hydroxycholesterol Is an Endogenous Ligand for Liver X Receptor in Cholesterol-loaded Cells

The Journal of biological chemistry, 2001-10, Vol.276 (42), p.38378-38387

2001

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A Potent Synthetic LXR Agonist Is More Effective than Cholesterol Loading at Inducing ABCA1 mRNA and Stimulating Cholesterol Efflux

The Journal of biological chemistry, 2002-03, Vol.277 (12), p.10021-10027

2002

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Guttiferone I, a New Prenylated Benzophenone from Garcinia humilis as a Liver X Receptor Ligand

Journal of natural products (Washington, D.C.), 2005-04, Vol.68 (4), p.617-619

2005

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Evaluation of endo- and exo-aryl-substitutions and central scaffold modifications on diphenyl substituted alkanes as 5-lipoxygenase activating protein inhibitors

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (12), p.4133-4138

2012

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Nicotinic acid and DP1 blockade: studies in mouse models of atherosclerosis[S]

Journal of lipid research, 2013-01, Vol.54 (1), p.177-188

2013

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Diterpenoid, Steroid, and Triterpenoid Agonists of Liver X Receptors from Diversified Terrestrial Plants and Marine Sources

Journal of natural products (Washington, D.C.), 2005-08, Vol.68 (8), p.1247-1252

2005

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Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway

Journal of lipid research, 2002-06, Vol.43 (6), p.952-959

2002

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A Novel Liver X Receptor Agonist Establishes Species Differences in the Regulation of Cholesterol 7α-Hydroxylase (CYP7a)

Endocrinology (Philadelphia), 2002-07, Vol.143 (7), p.2548-2558

2002

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Anthrabenzoxocinones from Streptomyces sp. as Liver X Receptor Ligands and Antibacterial Agents

Journal of natural products (Washington, D.C.), 2005-09, Vol.68 (9), p.1437-1440

2005

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Absolute Properties of the Main-Sequence Eclipsing Binary Star EY Cephei

The Astronomical journal, 2006-05, Vol.131 (5), p.2664-2672

2006

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Steroidal and Triterpenoidal Fungal Metabolites as Ligands of Liver X Receptors

Journal of antibiotics, 2005-09, Vol.58 (9), p.559-565

2005

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Dual Mechanisms of ABCA1 Regulation by Geranylgeranyl Pyrophosphate

The Journal of biological chemistry, 2001-12, Vol.276 (52), p.48702-48708

2001

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Design, synthesis, and structure–activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis

Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (20), p.4574-4578

2005

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Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters

Bioorganic & medicinal chemistry letters, 2005-06, Vol.15 (11), p.2824-2828

2005

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Discovery of the Predicted 2010 Eruption and the Pre-eruption Light Curve for Recurrent Nova U Scorpii

The Astronomical journal, 2010-10, Vol.140 (4), p.925-jQuery1323899041442='46'

2010

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Development of a high-capacity homogeneous fluorescent assay for the measurement of leukotriene B4

Analytical biochemistry, 2006-02, Vol.349 (1), p.129-135

2006

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Miniaturization of cell-based beta-lactamase-dependent FRET assays to ultra-high throughput formats to identify agonists of human liver X receptors

Assay and drug development technologies, 2003-12, Vol.1 (6), p.777-787

2003

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Reducing Competitive Suppression of a Rare Annual Forb by Restoring Native California Perennial Grasslands

Restoration ecology, 2000-03, Vol.8 (1), p.18-29

2000

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Metal Impurities Cause False Positives in High-Throughput Screening Campaigns

ACS medicinal chemistry letters, 2013-02, Vol.4 (2), p.197-200

2013

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Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy

Arthritis research & therapy, 2013-10, Vol.15 (5), p.R146-R146

2013

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Liver X receptor agonists as potential therapeutic agents for dyslipidemia and atherosclerosis

Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors

nuclear membrane organization of leukotriene synthesis

Different roles of liver X receptor α and β in lipid metabolism: Effects of an α-selective and a dual agonist in mice deficient in each subtype

27-Hydroxycholesterol Is an Endogenous Ligand for Liver X Receptor in Cholesterol-loaded Cells

A Potent Synthetic LXR Agonist Is More Effective than Cholesterol Loading at Inducing ABCA1 mRNA and Stimulating Cholesterol Efflux

Guttiferone I, a New Prenylated Benzophenone from Garcinia humilis as a Liver X Receptor Ligand

Evaluation of endo- and exo-aryl-substitutions and central scaffold modifications on diphenyl substituted alkanes as 5-lipoxygenase activating protein inhibitors

Nicotinic acid and DP1 blockade: studies in mouse models of atherosclerosis[S]

Diterpenoid, Steroid, and Triterpenoid Agonists of Liver X Receptors from Diversified Terrestrial Plants and Marine Sources

Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway

A Novel Liver X Receptor Agonist Establishes Species Differences in the Regulation of Cholesterol 7α-Hydroxylase (CYP7a)

Anthrabenzoxocinones from Streptomyces sp. as Liver X Receptor Ligands and Antibacterial Agents

Absolute Properties of the Main-Sequence Eclipsing Binary Star EY Cephei

Steroidal and Triterpenoidal Fungal Metabolites as Ligands of Liver X Receptors

Dual Mechanisms of ABCA1 Regulation by Geranylgeranyl Pyrophosphate

Design, synthesis, and structure–activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis

Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters

Discovery of the Predicted 2010 Eruption and the Pre-eruption Light Curve for Recurrent Nova U Scorpii

Development of a high-capacity homogeneous fluorescent assay for the measurement of leukotriene B4

Miniaturization of cell-based beta-lactamase-dependent FRET assays to ultra-high throughput formats to identify agonists of human liver X receptors

Reducing Competitive Suppression of a Rare Annual Forb by Restoring Native California Perennial Grasslands

Metal Impurities Cause False Positives in High-Throughput Screening Campaigns

3‑Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models

Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy

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