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Inhibition of skin carcinomas but not papillomas by sphingosine, N-methylsphingosine, and N-acetylsphingosine

Nutrition and cancer, 1998-01, Vol.31 (2), p.119-126

1998

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Fumonisin toxicity and sphingolipid biosynthesis

Advances in experimental medicine and biology, 1996, Vol.392, p.297

1996

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Synthesis and Protein Kinase C Inhibitory Activities of Balanol Analogs with Replacement of the Perhydroazepine Moiety

Journal of medicinal chemistry, 1997-01, Vol.40 (2), p.226-235

1997

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Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor

The Journal of biological chemistry, 1998-07, Vol.273 (30), p.19060

1998

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Identification of ammonium ion and 2,6-bis(omega-aminobutyl)- 3, 5-diiminopiperazine as endogenous factors that account for the "burst" of sphingosine upon changing the medium of J774 cells in culture

The Journal of biological chemistry, 1999-11, Vol.274 (48), p.33875-33880

1999

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Sphingoid bases and de novo ceramide synthesis: enzymes involved, pharmacology and mechanisms of action

Pharmacological research, 2003-05, Vol.47 (5), p.373-381

2003

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Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentanol produces a toxic metabolite of hydrolyzed fumonisin, AP sub(1), and a new category of ceramide synthase inhibitor

The Journal of biological chemistry, 1998-07, Vol.273 (30), p.19060-19064

1998

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Main group metal halide complexes with sterically hindered thioureas XI. Complexes of antimony(III) and bismuth(III) chlorides with a new bidentate thiourea — 1,1′-methylenebis(3-methyl-2H-imidazole-2-thione)

Inorganica Chimica Acta, 1989-11, Vol.165 (2), p.173-178

1989

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Increasing the cellular PKC inhibitory activity of balanol: A study of ester analogs

Bioorganic & medicinal chemistry letters, 1995-09, Vol.5 (18), p.2133-2138

1995

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Ring size effect in the PKC inhibitory activities of perhydroazepine analogs of balanol

Bioorganic & medicinal chemistry letters, 1995-09, Vol.5 (18), p.2151-2154

1995

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ChemInform Abstract: Main Group Metal Halide Complexes with Sterically Hindered Thioureas. Part 11. Complexes of Antimony(III) and Bismuth(III) Chlorides with a New Bidentate Thiourea ‐ 1,1′‐Methylenebis(3‐methyl‐2H‐imidazole‐2‐thione)

ChemInform, 1990-03, Vol.21 (12), p.no-no

1990

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ChemInform Abstract: Ring Size Effect in the PKC Inhibitory Activities of Perhydroazepine Analogues of Balanol

ChemInform, 1996-01, Vol.27 (2), p.no-no

1996

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Discovery of Dihydropyrrolo[1,2‑a]pyrazin-3(4H)‑one-Based Second-Generation GluN2C- and GluN2D-Selective Positive Allosteric Modulators (PAMs) of the N‑Methyl‑d‑Aspartate (NMDA) Receptor

Journal of medicinal chemistry, 2020-07, Vol.63 (14), p.7569-7600

2020

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The Bioactive Protein-Ligand Conformation of GluN2C-Selective Positive Allosteric Modulators Bound to the NMDA Receptor

Molecular pharmacology, 2018-02, Vol.93 (2), p.141-156

2018

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Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells. Evidence that ceramide may mediate sphingosine action

The Journal of biological chemistry, 1991-08, Vol.266 (24), p.16092-16097

1991

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Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds

Biochemistry (Easton), 1989-04, Vol.28 (8), p.3138-3145

1989

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A stereoselective synthesis of sphingosine, a protein kinase c inhibitor

Tetrahedron letters, 1988, Vol.29 (25), p.3037-3040

1988

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Influences of sphingosine on two-stage skin tumorigenesis in Sencar mice

Cancer letters, 1992-02, Vol.62 (1), p.35-42

1992

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Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells : evidence that ceramide may mediae sphingosine action

The Journal of biological chemistry, 1991, Vol.266 (24), p.16092-16097

1991

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Inhibition of skin carcinomas but not papillomas by sphingosine, N-methylsphingosine, and N-acetylsphingosine

Fumonisin toxicity and sphingolipid biosynthesis

Synthesis and Protein Kinase C Inhibitory Activities of Balanol Analogs with Replacement of the Perhydroazepine Moiety

Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor

Identification of ammonium ion and 2,6-bis(omega-aminobutyl)- 3, 5-diiminopiperazine as endogenous factors that account for the "burst" of sphingosine upon changing the medium of J774 cells in culture

Sphingoid bases and de novo ceramide synthesis: enzymes involved, pharmacology and mechanisms of action

Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentanol produces a toxic metabolite of hydrolyzed fumonisin, AP sub(1), and a new category of ceramide synthase inhibitor

Main group metal halide complexes with sterically hindered thioureas XI. Complexes of antimony(III) and bismuth(III) chlorides with a new bidentate thiourea — 1,1′-methylenebis(3-methyl-2H-imidazole-2-thione)

Increasing the cellular PKC inhibitory activity of balanol: A study of ester analogs

Ring size effect in the PKC inhibitory activities of perhydroazepine analogs of balanol

ChemInform Abstract: Main Group Metal Halide Complexes with Sterically Hindered Thioureas. Part 11. Complexes of Antimony(III) and Bismuth(III) Chlorides with a New Bidentate Thiourea ‐ 1,1′‐Methylenebis(3‐methyl‐2H‐imidazole‐2‐thione)

ChemInform Abstract: Ring Size Effect in the PKC Inhibitory Activities of Perhydroazepine Analogues of Balanol

Discovery of Dihydropyrrolo[1,2‑a]pyrazin-3(4H)‑one-Based Second-Generation GluN2C- and GluN2D-Selective Positive Allosteric Modulators (PAMs) of the N‑Methyl‑d‑Aspartate (NMDA) Receptor

The Bioactive Protein-Ligand Conformation of GluN2C-Selective Positive Allosteric Modulators Bound to the NMDA Receptor

Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells. Evidence that ceramide may mediate sphingosine action

Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds

A stereoselective synthesis of sphingosine, a protein kinase c inhibitor

Influences of sphingosine on two-stage skin tumorigenesis in Sencar mice

Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells : evidence that ceramide may mediae sphingosine action

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