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Further Evidence of Dopamine Transporter Dysregulation in ADHD: A Controlled PET Imaging Study Using Altropane

Biological psychiatry (1969), 2007-11, Vol.62 (9), p.1059-1061

2007

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1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) Analogues: A Promising Class of Monoamine Uptake Inhibitors

Journal of medicinal chemistry, 2006-02, Vol.49 (4), p.1420-1432

2006

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Synthesis and Discovery of Arylpiperidinylquinazolines: New Inhibitors of the Vesicular Monoamine Transporter

Journal of medicinal chemistry, 2018-10, Vol.61 (20), p.9121-9131

2018

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Dopamine transporter (DAT) inhibitors alleviate specific parkinsonian deficits in monkeys: association with DAT occupancy in vivo

The Journal of pharmacology and experimental therapeutics, 2006-11, Vol.319 (2), p.570-585

2006

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Drug scheduling of stimulants: Dopamine transporter effects, brain occupancy and abuse liability

Drug and alcohol dependence, 2015-11, Vol.156, p.e138-e138

2015

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2-Carbomethoxy-3-aryl-8-bicyclo[3.2.1]octanes: Potent Non-Nitrogen Inhibitors of Monoamine Transporters

Journal of medicinal chemistry, 2000-08, Vol.43 (16), p.2982-2991

2000

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Synthesis and structure–activity relationship studies of 3-biaryl-8-oxabicyclo[3.2.1]octane-2-carboxylic acid methyl esters

Bioorganic & medicinal chemistry, 2012-04, Vol.20 (8), p.2762-2772

2012

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The synthesis and biological evaluation of 2-(3-methyl or 3-phenylisoxazol-5-yl)-3-aryl-8-thiabicyclo[3.2.1]octanes

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.48-51

2011

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The synthesis of bivalent 2β-carbomethoxy-3β-(3,4-dichlorophenyl)-8-heterobicyclo[3.2.1]octanes as probes for proximal binding sites on the dopamine and serotonin transporters

Bioorganic & medicinal chemistry, 2008-02, Vol.16 (4), p.1832-1841

2008

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Synthesis and Evaluation of Dopamine and Serotonin Transporter Inhibition by Oxacyclic and Carbacyclic Analogues of Methylphenidate

Journal of medicinal chemistry, 2003-04, Vol.46 (8), p.1538-1545

2003

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Synthesis of 8-thiabicyclo[3.2.1]octanes and their binding affinity for the dopamine and serotonin transporters

Bioorganic & medicinal chemistry, 2007-01, Vol.15 (2), p.1067-1082

2007

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2-Carbomethoxy-3-aryl-8-oxabicyclo[3.2.1]octanes: Potent Non-Nitrogen Inhibitors of Monoamine Transporters

Journal of medicinal chemistry, 1997-08, Vol.40 (17), p.2661-2673

1997

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Synthesis of 6- and 7- Hydroxy-8-azabicyclo[3.2.1]octanes and Their Binding Affinity for the Dopamine and Serotonin Transporters

Journal of medicinal chemistry, 2001-08, Vol.44 (16), p.2619-2635

2001

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[11C,127I] Altropane: A highly selective ligand for PET imaging of dopamine transporter sites

Synapse (New York, N.Y.), 2001-03, Vol.39 (4), p.332-342

2001

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Synthesis of 8-thiabicyclo[3.2.1]oct-2-enes and their binding affinity for the dopamine and serotonin transporters

Bioorganic & medicinal chemistry letters, 2004-12, Vol.14 (24), p.6007-6010

2004

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Synthesis and biological activity of 2-Carbomethoxy-3-catechol-8-azabicyclo[3.2.1]octanes

Bioorganic & medicinal chemistry letters, 2003-11, Vol.13 (22), p.4133-4137

2003

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The Discovery of an Unusually Selective and Novel Cocaine Analog: Difluoropine. Synthesis and Inhibition of Binding at Cocaine Recognition Sites

Journal of medicinal chemistry, 1994-06, Vol.37 (13), p.2001-2010

1994

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Design and synthesis of an irreversible dopamine-sparing cocaine antagonist

Bioorganic & medicinal chemistry, 2002-11, Vol.10 (11), p.3583-3591

2002

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A Technetium-99m SPECT Imaging Agent Which Targets the Dopamine Transporter in Primate Brain

Journal of medicinal chemistry, 1997-06, Vol.40 (12), p.1835-1844

1997

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Non-amine-based dopamine transporter (reuptake) inhibitors retain properties of amine-based progenitors

European journal of pharmacology, 2003-10, Vol.479 (1), p.41-51

2003

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Altropane, a SPECT or PET imaging probe for dopamine neurons: III. Human dopamine transporter in postmortem normal and Parkinson's diseased brain

Synapse (New York, N.Y.), 1998-06, Vol.29 (2), p.116-127

1998

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2-Carbomethoxy-3-(diarylmethoxy)-1αH,5αH-tropane Analogs: Synthesis and Inhibition of Binding at the Dopamine Transporter and Comparison with Piperazines of the GBR Series

Journal of medicinal chemistry, 1996-01, Vol.39 (2), p.371-379

1996

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Synthesis and structure activity relationship studies of 3-biaryl-8-oxa-bicyclo[3.2.1]octane-2-carboxylic acid methyl esters

Bioorganic & medicinal chemistry, 2012-02, Vol.20 (8), p.2762-2772

2012

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A second-generation 99m technetium single photon emission computed tomography agent that provides in vivo images of the dopamine transporter in primate brain

Journal of medicinal chemistry, 2003-07, Vol.46 (16), p.3483-3496

2003

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A Second-Generation 99mTechnetium Single Photon Emission Computed Tomography Agent That Provides in Vivo Images of the Dopamine Transporter in Primate Brain

Journal of medicinal chemistry, 2003-07, Vol.46 (16), p.3483-3496

2003

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Further Evidence of Dopamine Transporter Dysregulation in ADHD: A Controlled PET Imaging Study Using Altropane

1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) Analogues: A Promising Class of Monoamine Uptake Inhibitors

Synthesis and Discovery of Arylpiperidinylquinazolines: New Inhibitors of the Vesicular Monoamine Transporter

Dopamine transporter (DAT) inhibitors alleviate specific parkinsonian deficits in monkeys: association with DAT occupancy in vivo

Drug scheduling of stimulants: Dopamine transporter effects, brain occupancy and abuse liability

2-Carbomethoxy-3-aryl-8-bicyclo[3.2.1]octanes: Potent Non-Nitrogen Inhibitors of Monoamine Transporters

Synthesis and structure–activity relationship studies of 3-biaryl-8-oxabicyclo[3.2.1]octane-2-carboxylic acid methyl esters

The synthesis and biological evaluation of 2-(3-methyl or 3-phenylisoxazol-5-yl)-3-aryl-8-thiabicyclo[3.2.1]octanes

The synthesis of bivalent 2β-carbomethoxy-3β-(3,4-dichlorophenyl)-8-heterobicyclo[3.2.1]octanes as probes for proximal binding sites on the dopamine and serotonin transporters

Synthesis and Evaluation of Dopamine and Serotonin Transporter Inhibition by Oxacyclic and Carbacyclic Analogues of Methylphenidate

Synthesis of 8-thiabicyclo[3.2.1]octanes and their binding affinity for the dopamine and serotonin transporters

2-Carbomethoxy-3-aryl-8-oxabicyclo[3.2.1]octanes: Potent Non-Nitrogen Inhibitors of Monoamine Transporters

Synthesis of 6- and 7- Hydroxy-8-azabicyclo[3.2.1]octanes and Their Binding Affinity for the Dopamine and Serotonin Transporters

[11C,127I] Altropane: A highly selective ligand for PET imaging of dopamine transporter sites

Synthesis of 8-thiabicyclo[3.2.1]oct-2-enes and their binding affinity for the dopamine and serotonin transporters

Synthesis and biological activity of 2-Carbomethoxy-3-catechol-8-azabicyclo[3.2.1]octanes

The Discovery of an Unusually Selective and Novel Cocaine Analog: Difluoropine. Synthesis and Inhibition of Binding at Cocaine Recognition Sites

Design and synthesis of an irreversible dopamine-sparing cocaine antagonist

A Technetium-99m SPECT Imaging Agent Which Targets the Dopamine Transporter in Primate Brain

Non-amine-based dopamine transporter (reuptake) inhibitors retain properties of amine-based progenitors

Altropane, a SPECT or PET imaging probe for dopamine neurons: III. Human dopamine transporter in postmortem normal and Parkinson's diseased brain

2-Carbomethoxy-3-(diarylmethoxy)-1αH,5αH-tropane Analogs: Synthesis and Inhibition of Binding at the Dopamine Transporter and Comparison with Piperazines of the GBR Series

Synthesis and structure activity relationship studies of 3-biaryl-8-oxa-bicyclo[3.2.1]octane-2-carboxylic acid methyl esters

A second-generation 99m technetium single photon emission computed tomography agent that provides in vivo images of the dopamine transporter in primate brain

A Second-Generation 99mTechnetium Single Photon Emission Computed Tomography Agent That Provides in Vivo Images of the Dopamine Transporter in Primate Brain

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