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Shiga Toxin (Stx) Classification, Structure, and Function

Microbiology spectrum, 2014-08, Vol.2 (4), p.EHEC-0024-2013

2014

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Multicenter Evaluation of a Sequence-Based Protocol for Subtyping Shiga Toxins and Standardizing Stx Nomenclature

Journal of Clinical Microbiology, 2012-09, Vol.50 (9), p.2951-2963

2012

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Shiga toxin (Stx) type 2‐induced increase in O‐linked N‐acetyl glucosamine protein modification: a new therapeutic target?

EMBO molecular medicine, 2022-01, Vol.14 (1), p.e15389-n/a

2022

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Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model

Toxins, 2023-03, Vol.15 (3), p.207

2023

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Dietary choice affects Shiga toxin-producing Escherichia coli (STEC) O157:H7 colonization and disease

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (23), p.E2126-E2133

2013

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Comparisons of native Shiga toxins (Stxs) type 1 and 2 with chimeric toxins indicate that the source of the binding subunit dictates degree of toxicity

PloS one, 2014-03, Vol.9 (3), p.e93463

2014

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Clinical isolates of Shiga toxin 1a-producing Shigella flexneri with an epidemiological link to recent travel to Hispañiola

Emerging infectious diseases, 2014-10, Vol.20 (10), p.1669-1677

2014

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Differences in the Shiga Toxin (Stx) 2a Phage Regulatory Switch Region Influence Stx2 Localization and Virulence of Stx-Producing Escherichia coli in Mice

Microorganisms (Basel), 2023-07, Vol.11 (8), p.1925

2023

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The Presence of the pAA Plasmid in the German O104:H4 Shiga Toxin Type 2a (Stx2a)-Producing Enteroaggregative Escherichia coli Strain Promotes the Translocation of Stx2a Across an Epithelial Cell Monolayer

The Journal of infectious diseases, 2014-12, Vol.210 (12), p.1909-1919

2014

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Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7

The Journal of biological chemistry, 2004-06, Vol.279 (26), p.27511-27517

2004

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Virulence of the Shiga Toxin Type 2-Expressing Escherichia coli O104:H4 German Outbreak Isolate in Two Animal Models

Infection and Immunity, 2013-05, Vol.81 (5), p.1562-1574

2013

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The Virulence of Escherichia coli O157:H7 Isolates in Mice Depends on Shiga Toxin Type 2a (Stx2a)-Induction and High Levels of Stx2a in Stool

Frontiers in cellular and infection microbiology, 2020-02, Vol.10, p.62-62

2020

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Human Intestinal Tissue and Cultured Colonic Cells Contain Globotriaosylceramide Synthase mRNA and the Alternate Shiga Toxin Receptor Globotetraosylceramide

Infection and Immunity, 2010-11, Vol.78 (11), p.4488-4499

2010

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The Role of the AggR Regulon in the Virulence of the Shiga Toxin-Producing Enteroaggregative Escherichia coli Epidemic O104:H4 Strain in Mice

Frontiers in microbiology, 2019-08, Vol.10, p.1824-1824

2019

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Extracellular components in enteroaggregative Escherichia coli biofilm and impact of treatment with proteinase K, DNase or sodium metaperiodate

Frontiers in cellular and infection microbiology, 2024-05, Vol.14, p.1379206

2024

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Shiga Toxin–Producing Escherichia coli in Montana: Bacterial Genotypes and Clinical Profiles

The Journal of infectious diseases, 2003-09, Vol.188 (5), p.719-729

2003

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Switching Shiga Toxin (Stx) Type from Stx2d to Stx2a but Not Stx2c Alters Virulence of Stx-Producing Escherichia coli (STEC) Strain B2F1 in Streptomycin (Str)-Treated Mice

Toxins, 2021-01, Vol.13 (1), p.64

2021

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Genetic and Virulence Profiles of Enteroaggregative Escherichia coli (EAEC) Isolated From Deployed Military Personnel (DMP) With Travelers' Diarrhea

Frontiers in cellular and infection microbiology, 2020-05, Vol.10, p.200-200

2020

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Ricin crosses polarized human intestinal cells and intestines of ricin-gavaged mice without evident damage and then disseminates to mouse kidneys

PloS one, 2013-07, Vol.8 (7), p.e69706

2013

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New Therapeutic Developments against Shiga Toxin-Producing Escherichia coli

Microbiology spectrum, 2014-10, Vol.2 (5)

2014

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Reduced Toxicity of Shiga Toxin (Stx) Type 2c in Mice Compared to Stx2d Is Associated with Instability of Stx2c Holotoxin

Toxins, 2015-06, Vol.7 (6), p.2306-2320

2015

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Mouse Model of Hemolytic-Uremic Syndrome Caused by Endotoxin-Free Shiga Toxin 2 (Stx2) and Protection from Lethal Outcome by Anti-Stx2 Antibody

Infection and Immunity, 2008-10, Vol.76 (10), p.4469-4478

2008

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Shiga toxin type 2dact displays increased binding to globotriaosylceramide in vitro and increased lethality in mice after activation by elastase

Toxins, 2013-11, Vol.5 (11), p.2074-2092

2013

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Shiga Toxin (Stx) Type 1a Reduces the Oral Toxicity of Stx Type 2a

The Journal of infectious diseases, 2016-04, Vol.213 (8), p.1271-1279

2016

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Efficacy of EHEC gold nanoparticle vaccines evaluated with the Shiga toxin-producing Citrobacter rodentium mouse model

Microbiology spectrum, 2024-01, Vol.12 (1), p.e0226123-e0226123

2024

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Shiga Toxin (Stx) Classification, Structure, and Function

Multicenter Evaluation of a Sequence-Based Protocol for Subtyping Shiga Toxins and Standardizing Stx Nomenclature

Shiga toxin (Stx) type 2‐induced increase in O‐linked N‐acetyl glucosamine protein modification: a new therapeutic target?

Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model

Dietary choice affects Shiga toxin-producing Escherichia coli (STEC) O157:H7 colonization and disease

Comparisons of native Shiga toxins (Stxs) type 1 and 2 with chimeric toxins indicate that the source of the binding subunit dictates degree of toxicity

Clinical isolates of Shiga toxin 1a-producing Shigella flexneri with an epidemiological link to recent travel to Hispañiola

Differences in the Shiga Toxin (Stx) 2a Phage Regulatory Switch Region Influence Stx2 Localization and Virulence of Stx-Producing Escherichia coli in Mice

The Presence of the pAA Plasmid in the German O104:H4 Shiga Toxin Type 2a (Stx2a)-Producing Enteroaggregative Escherichia coli Strain Promotes the Translocation of Stx2a Across an Epithelial Cell Monolayer

Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7

Virulence of the Shiga Toxin Type 2-Expressing Escherichia coli O104:H4 German Outbreak Isolate in Two Animal Models

The Virulence of Escherichia coli O157:H7 Isolates in Mice Depends on Shiga Toxin Type 2a (Stx2a)-Induction and High Levels of Stx2a in Stool

Human Intestinal Tissue and Cultured Colonic Cells Contain Globotriaosylceramide Synthase mRNA and the Alternate Shiga Toxin Receptor Globotetraosylceramide

The Role of the AggR Regulon in the Virulence of the Shiga Toxin-Producing Enteroaggregative Escherichia coli Epidemic O104:H4 Strain in Mice

Extracellular components in enteroaggregative Escherichia coli biofilm and impact of treatment with proteinase K, DNase or sodium metaperiodate

Shiga Toxin–Producing Escherichia coli in Montana: Bacterial Genotypes and Clinical Profiles

Switching Shiga Toxin (Stx) Type from Stx2d to Stx2a but Not Stx2c Alters Virulence of Stx-Producing Escherichia coli (STEC) Strain B2F1 in Streptomycin (Str)-Treated Mice

Genetic and Virulence Profiles of Enteroaggregative Escherichia coli (EAEC) Isolated From Deployed Military Personnel (DMP) With Travelers' Diarrhea

Ricin crosses polarized human intestinal cells and intestines of ricin-gavaged mice without evident damage and then disseminates to mouse kidneys

New Therapeutic Developments against Shiga Toxin-Producing Escherichia coli

Reduced Toxicity of Shiga Toxin (Stx) Type 2c in Mice Compared to Stx2d Is Associated with Instability of Stx2c Holotoxin

Mouse Model of Hemolytic-Uremic Syndrome Caused by Endotoxin-Free Shiga Toxin 2 (Stx2) and Protection from Lethal Outcome by Anti-Stx2 Antibody

Shiga toxin type 2dact displays increased binding to globotriaosylceramide in vitro and increased lethality in mice after activation by elastase

Shiga Toxin (Stx) Type 1a Reduces the Oral Toxicity of Stx Type 2a

Efficacy of EHEC gold nanoparticle vaccines evaluated with the Shiga toxin-producing Citrobacter rodentium mouse model

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