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High Performance Marine and Terrestrial Bioadhesives and the Biomedical Applications They Have Inspired

Molecules (Basel, Switzerland), 2022-12, Vol.27 (24), p.8982

Melrose, James

2022

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Fractone Stem Cell Niche Components Provide Intuitive Clues in the Design of New Therapeutic Procedures/Biomatrices for Neural Repair

International journal of molecular sciences, 2022-05, Vol.23 (9), p.5148

Melrose, James

2022

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The Potential of Flavonoids and Flavonoid Metabolites in the Treatment of Neurodegenerative Pathology in Disorders of Cognitive Decline

Antioxidants, 2023-03, Vol.12 (3), p.663

Melrose, James

2023

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The Glucosinolates: A Sulphur Glucoside Family of Mustard Anti-Tumour and Antimicrobial Phytochemicals of Potential Therapeutic Application

Biomedicines, 2019-08, Vol.7 (3), p.62

Melrose, James

2019

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Mucin-like glycopolymer gels in electrosensory tissues generate cues which direct electrolocation in amphibians and neuronal activation in mammals

Neural regeneration research, 2019-07, Vol.14 (7), p.1191-1195

Melrose, James

2019

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The Importance of the Knee Joint Meniscal Fibrocartilages as Stabilizing Weight Bearing Structures Providing Global Protection to Human Knee-Joint Tissues

Cells (Basel, Switzerland), 2019-04, Vol.8 (4), p.324

Melrose, James

2019

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The Glycosaminoglycan Side Chains and Modular Core Proteins of Heparan Sulphate Proteoglycans and the Varied Ways They Provide Tissue Protection by Regulating Physiological Processes and Cellular Behaviour

International journal of molecular sciences, 2023-09, Vol.24 (18), p.14101

2023

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Perlecan in Pericellular Mechanosensory Cell-Matrix Communication, Extracellular Matrix Stabilisation and Mechanoregulation of Load-Bearing Connective Tissues

International journal of molecular sciences, 2021-03, Vol.22 (5), p.2716

2021

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Lumican, a Multifunctional Cell Instructive Biomarker Proteoglycan Has Novel Roles as a Marker of the Hypercoagulative State of Long Covid Disease

International journal of molecular sciences, 2024-02, Vol.25 (5), p.2825

2024

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The CNS/PNS Extracellular Matrix Provides Instructive Guidance Cues to Neural Cells and Neuroregulatory Proteins in Neural Development and Repair

International journal of molecular sciences, 2021-05, Vol.22 (11), p.5583

2021

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Intervertebral disc degeneration and how it leads to low back pain

JOR-spine, 2023-03, Vol.6 (1), p.e1231-n/a

2023

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HS, an Ancient Molecular Recognition and Information Storage Glycosaminoglycan, Equips HS-Proteoglycans with Diverse Matrix and Cell-Interactive Properties Operative in Tissue Development and Tissue Function in Health and Disease

International journal of molecular sciences, 2023-01, Vol.24 (2), p.1148

2023

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Regulation of FGF-2, FGF-18 and Transcription Factor Activity by Perlecan in the Maturational Development of Transitional Rudiment and Growth Plate Cartilages and in the Maintenance of Permanent Cartilage Homeostasis

International journal of molecular sciences, 2022-02, Vol.23 (4), p.1934

2022

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The multifaceted roles of perlecan in fibrosis

Matrix biology, 2018-08, Vol.68-69, p.150-166

2018

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Keratan sulfate (KS)‐proteoglycans and neuronal regulation in health and disease: the importance of KS‐glycodynamics and interactive capability with neuroregulatory ligands

Journal of neurochemistry, 2019-04, Vol.149 (2), p.170-194

Melrose, James

2019

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What Are the Potential Roles of Nuclear Perlecan and Other Heparan Sulphate Proteoglycans in the Normal and Malignant Phenotype

International journal of molecular sciences, 2021-04, Vol.22 (9), p.4415

2021

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Diverse and multifunctional roles for perlecan (HSPG2) in repair of the intervertebral disc

JOR-spine, 2024-09, Vol.7 (3), p.e1362-n/a

2024

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The Role of Heparan Sulfate in Inflammation, and the Development of Biomimetics as Anti-Inflammatory Strategies

Journal of Histochemistry & Cytochemistry, 2018-04, Vol.66 (4), p.321-336

2018

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Aggrecan, the Primary Weight-Bearing Cartilage Proteoglycan, Has Context-Dependent, Cell-Directive Properties in Embryonic Development and Neurogenesis: Aggrecan Glycan Side Chain Modifications Convey Interactive Biodiversity

Biomolecules (Basel, Switzerland), 2020-08, Vol.10 (9), p.1244

2020

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Perlecan, a modular instructive proteoglycan with diverse functional properties

The international journal of biochemistry & cell biology, 2020-11, Vol.128, p.105849-105849, Article 105849

Melrose, James

2020

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Pentosan Polysulfate Affords Pleotropic Protection to Multiple Cells and Tissues

Pharmaceuticals (Basel, Switzerland), 2023-03, Vol.16 (3), p.437

2023

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Hippo cell signaling and HS-proteoglycans regulate tissue form and function, age-dependent maturation, extracellular matrix remodeling, and repair

American Journal of Physiology: Cell Physiology, 2024-03, Vol.326 (3), p.C810-C828

Melrose, James

2024

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Cancer Metastasis: The Role of the Extracellular Matrix and the Heparan Sulfate Proteoglycan Perlecan

Frontiers in oncology, 2020-01, Vol.9, p.1482-1482

2020

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Proteoglycan degradation by the ADAMTS family of proteinases

Biochimica et biophysica acta, 2011-12, Vol.1812 (12), p.1616-1629

2011

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CNS/PNS proteoglycans functionalize neuronal and astrocyte niche microenvironments optimizing cellular activity by preserving membrane polarization dynamics, ionic microenvironments, ion fluxes, neuronal activation, and network neurotransductive capacity

Journal of neuroscience research, 2024-07, Vol.102 (7), p.e25361-n/a

Melrose, James

2024

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High Performance Marine and Terrestrial Bioadhesives and the Biomedical Applications They Have Inspired

Fractone Stem Cell Niche Components Provide Intuitive Clues in the Design of New Therapeutic Procedures/Biomatrices for Neural Repair

The Potential of Flavonoids and Flavonoid Metabolites in the Treatment of Neurodegenerative Pathology in Disorders of Cognitive Decline

The Glucosinolates: A Sulphur Glucoside Family of Mustard Anti-Tumour and Antimicrobial Phytochemicals of Potential Therapeutic Application

Mucin-like glycopolymer gels in electrosensory tissues generate cues which direct electrolocation in amphibians and neuronal activation in mammals

The Importance of the Knee Joint Meniscal Fibrocartilages as Stabilizing Weight Bearing Structures Providing Global Protection to Human Knee-Joint Tissues

The Glycosaminoglycan Side Chains and Modular Core Proteins of Heparan Sulphate Proteoglycans and the Varied Ways They Provide Tissue Protection by Regulating Physiological Processes and Cellular Behaviour

Perlecan in Pericellular Mechanosensory Cell-Matrix Communication, Extracellular Matrix Stabilisation and Mechanoregulation of Load-Bearing Connective Tissues

Lumican, a Multifunctional Cell Instructive Biomarker Proteoglycan Has Novel Roles as a Marker of the Hypercoagulative State of Long Covid Disease

The CNS/PNS Extracellular Matrix Provides Instructive Guidance Cues to Neural Cells and Neuroregulatory Proteins in Neural Development and Repair

Intervertebral disc degeneration and how it leads to low back pain

HS, an Ancient Molecular Recognition and Information Storage Glycosaminoglycan, Equips HS-Proteoglycans with Diverse Matrix and Cell-Interactive Properties Operative in Tissue Development and Tissue Function in Health and Disease

Regulation of FGF-2, FGF-18 and Transcription Factor Activity by Perlecan in the Maturational Development of Transitional Rudiment and Growth Plate Cartilages and in the Maintenance of Permanent Cartilage Homeostasis

The multifaceted roles of perlecan in fibrosis

Keratan sulfate (KS)‐proteoglycans and neuronal regulation in health and disease: the importance of KS‐glycodynamics and interactive capability with neuroregulatory ligands

What Are the Potential Roles of Nuclear Perlecan and Other Heparan Sulphate Proteoglycans in the Normal and Malignant Phenotype

Diverse and multifunctional roles for perlecan (HSPG2) in repair of the intervertebral disc

The Role of Heparan Sulfate in Inflammation, and the Development of Biomimetics as Anti-Inflammatory Strategies

Aggrecan, the Primary Weight-Bearing Cartilage Proteoglycan, Has Context-Dependent, Cell-Directive Properties in Embryonic Development and Neurogenesis: Aggrecan Glycan Side Chain Modifications Convey Interactive Biodiversity

Perlecan, a modular instructive proteoglycan with diverse functional properties

Pentosan Polysulfate Affords Pleotropic Protection to Multiple Cells and Tissues

Hippo cell signaling and HS-proteoglycans regulate tissue form and function, age-dependent maturation, extracellular matrix remodeling, and repair

Cancer Metastasis: The Role of the Extracellular Matrix and the Heparan Sulfate Proteoglycan Perlecan

Proteoglycan degradation by the ADAMTS family of proteinases

CNS/PNS proteoglycans functionalize neuronal and astrocyte niche microenvironments optimizing cellular activity by preserving membrane polarization dynamics, ionic microenvironments, ion fluxes, neuronal activation, and network neurotransductive capacity

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