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Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade

Science translational medicine, 2018-01, Vol.10 (422)

2018

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The immunological consequences of radiation‐induced DNA damage

The Journal of pathology, 2019-04, Vol.247 (5), p.606-614

2019

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Human tumour immune evasion via TGF-β blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity

PloS one, 2011-09, Vol.6 (9), p.e22842

2011

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Glycolysis and Fatty Acid Oxidation Inhibition Improves Survival in Glioblastoma

Frontiers in oncology, 2021-03, Vol.11, p.633210

2021

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Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy

Nature communications, 2024-08, Vol.15 (1), p.6923-16, Article 6923

2024

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The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study

Frontiers in immunology, 2020-10, Vol.11, p.524968-524968

2020

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Enhancing anti-tumour innate immunity by targeting the DNA damage response and pattern recognition receptors in combination with radiotherapy

Frontiers in oncology, 2022-08, Vol.12, p.971959-971959

2022

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The case of oncolytic viruses versus the immune system: waiting on the judgment of Solomon

Human gene therapy, 2009-10, Vol.20 (10), p.1119

2009

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Harnessing radiotherapy-induced NK-cell activity by combining DNA damage–response inhibition and immune checkpoint blockade

Journal for immunotherapy of cancer, 2022-03, Vol.10 (3), p.e004306

2022

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Cell carriage, delivery, and selective replication of an oncolytic virus in tumor in patients

Science translational medicine, 2012-06, Vol.4 (138), p.138ra77

2012

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RIPK1‐mediated immunogenic cell death promotes anti‐tumour immunity against soft‐tissue sarcoma

EMBO molecular medicine, 2020-06, Vol.12 (6), p.e10979-n/a

2020

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Inflammatory microenvironment remodelling by tumour cells after radiotherapy

Nature reviews. Cancer, 2020-04, Vol.20 (4), p.203

2020

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Progress in clinical oncolytic virus-based therapy for hepatocellular carcinoma

Journal of general virology, 2015-07, Vol.96 (Pt 7), p.1533-1550

2015

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Immune-Mediated Antitumor Activity of Reovirus Is Required for Therapy and Is Independent of Direct Viral Oncolysis and Replication

Clinical cancer research, 2009-07, Vol.15 (13), p.4374-4381

2009

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Tumor Infection by Oncolytic Reovirus Primes Adaptive Antitumor Immunity

Clinical cancer research, 2008-11, Vol.14 (22), p.7358-7366

2008

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Cytotoxic and immune‐mediated killing of human colorectal cancer by reovirus‐loaded blood and liver mononuclear cells

International journal of cancer, 2013-05, Vol.132 (10), p.2327-2338

2013

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Intravenous Oncolytic Vaccinia Virus Therapy Results in a Differential Immune Response between Cancer Patients

Cancers, 2022-04, Vol.14 (9), p.2181

2022

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Internalization of Oncolytic Reovirus by Human Dendritic Cell Carriers Protects the Virus from Neutralization

Clinical cancer research, 2011-05, Vol.17 (9), p.2767-2776

2011

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Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway

BMC cancer, 2012-08, Vol.12 (1), p.368-368, Article 368

2012

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The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism

Molecular therapy. Oncolytics, 2020-03, Vol.16, p.238-249

2020

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Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mutant thyroid cancer

Journal for immunotherapy of cancer, 2020-08, Vol.8 (2), p.e000698

2020

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Plasmacytoid dendritic cells orchestrate innate and adaptive anti-tumor immunity induced by oncolytic coxsackievirus A21

Journal for immunotherapy of cancer, 2019-07, Vol.7 (1), p.164-164, Article 164

2019

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Enhanced In vitro and In vivo Cytotoxicity of Combined Reovirus and Radiotherapy

Clinical cancer research, 2008-02, Vol.14 (3), p.912-923

2008

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Phase I Trial of an ICAM-1-Targeted Immunotherapeutic-Coxsackievirus A21 (CVA21) as an Oncolytic Agent Against Non Muscle-Invasive Bladder Cancer

Clinical cancer research, 2019-10, Vol.25 (19), p.5818-5831

2019

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Heat Shock Protein 70 Induced During Tumor Cell Killing Induces Th1 Cytokines and Targets Immature Dendritic Cell Precursors to Enhance Antigen Uptake

The Journal of immunology (1950), 1999-08, Vol.163 (3), p.1398-1408

1999

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Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade

The immunological consequences of radiation‐induced DNA damage

Human tumour immune evasion via TGF-β blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity

Glycolysis and Fatty Acid Oxidation Inhibition Improves Survival in Glioblastoma

Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy

The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study

Enhancing anti-tumour innate immunity by targeting the DNA damage response and pattern recognition receptors in combination with radiotherapy

The case of oncolytic viruses versus the immune system: waiting on the judgment of Solomon

Harnessing radiotherapy-induced NK-cell activity by combining DNA damage–response inhibition and immune checkpoint blockade

Cell carriage, delivery, and selective replication of an oncolytic virus in tumor in patients

RIPK1‐mediated immunogenic cell death promotes anti‐tumour immunity against soft‐tissue sarcoma

Inflammatory microenvironment remodelling by tumour cells after radiotherapy

Progress in clinical oncolytic virus-based therapy for hepatocellular carcinoma

Immune-Mediated Antitumor Activity of Reovirus Is Required for Therapy and Is Independent of Direct Viral Oncolysis and Replication

Tumor Infection by Oncolytic Reovirus Primes Adaptive Antitumor Immunity

Cytotoxic and immune‐mediated killing of human colorectal cancer by reovirus‐loaded blood and liver mononuclear cells

Intravenous Oncolytic Vaccinia Virus Therapy Results in a Differential Immune Response between Cancer Patients

Internalization of Oncolytic Reovirus by Human Dendritic Cell Carriers Protects the Virus from Neutralization

Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway

The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism

Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mutant thyroid cancer

Plasmacytoid dendritic cells orchestrate innate and adaptive anti-tumor immunity induced by oncolytic coxsackievirus A21

Enhanced In vitro and In vivo Cytotoxicity of Combined Reovirus and Radiotherapy

Phase I Trial of an ICAM-1-Targeted Immunotherapeutic-Coxsackievirus A21 (CVA21) as an Oncolytic Agent Against Non Muscle-Invasive Bladder Cancer

Heat Shock Protein 70 Induced During Tumor Cell Killing Induces Th1 Cytokines and Targets Immature Dendritic Cell Precursors to Enhance Antigen Uptake

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